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Medicube vs Sesderma

Rated by Lovi 路 Unbiased, science-based skincare AI trained on real user outcomes 路 How the Fit score works

Medicube and Sesderma are distinguished skincare brands originating from South Korea and Spain, respectively. The Korean brand is adored for its thoughtfully formulated moisturizers, serums, toners, and masks featuring niacinamide, collagen, and hyaluronic acid, while the Spanish brand is beloved for advanced serums and meticulously engineered formulas. Both serve distinct needs, as the former suits dry and oily acne-prone skin best with targeted solutions like the AGE-R Booster Gel and Deep Lifting Peptide Eye Cream, whereas the latter suits sensitive, hyperpigmented, and aging skin best through products such as the Azelac RU Serum. Ultimately, they differ in their foundational ingredients and geographical origins, yet each delivers profound results through specialized active compounds.

Medicube is a Korean skincare brand founded in 2016 and owned by APR Corp..

medicubereviews.co.ukglossy.co

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Medicube and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Medicube vs Sesderma products

Medicube vs Sesderma serums and treatments

Questions and answers

Medicube or Sesderma: which is better?

Medicube offers a much larger variety of products across multiple categories with high Lovi fit levels for dry and oily skin, while Sesderma is represented by just a single serum on this page. Medicube products on this page are mostly fragrance-free, whereas the Sesderma product contains fragrance.

What is the difference between Medicube and Sesderma?

Medicube offers a large variety of skincare products well-suited for dry, oily, and oily acne-prone skin, while Sesderma is represented by just the Azelac RU Serum on this page. Most Medicube products list no fragrance, whereas Sesderma's serum includes fragrance.

Which is more affordable, Medicube or Sesderma?

Medicube offers a broader range of products on this page compared to Sesderma, but reviewers note that pricing issues are a concern for Medicube.

Which causes fewer breakouts, Medicube or Sesderma?

Medicube offers a wide range of products on this page that help with acne-prone skin, such as the Zero Pore Pad which has a High fit for acne-prone skin, whereas Sesderma features only one product on this page and does not highlight acne-prone skin as a primary fit. However, reviewers note that some Medicube products may occasionally cause irritation and breakouts.

Between Medicube and Sesderma, which brand offers more products that are formulated without fragrance?

Medicube offers significantly more products formulated without fragrance, with 23 of its 25 products on this page listing no fragrance. In contrast, Sesderma includes fragrance in all of its products listed on the page.

How do the founding years and countries of origin compare between Medicube and Sesderma?

Medicube was founded in South Korea in 2016, whereas Sesderma was founded in Spain in 1989.

What are the main negative and positive feedback points reported by reviewers for Medicube products?

Reviewers for Medicube products mostly mention deep hydration moisturizers, radiant glow, and smoother skin texture as positive points. On the negative side, reviewers often report sticky residue and small quantity and pricing issues.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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