Simple vs Sesderma
Simple and Sesderma are distinguished skincare brands that cater to those seeking gentle yet effective daily care. The British brand, established in 1960, is celebrated for its nurturing moisturizers, makeup removers, cleansers, and toners featuring niacinamide and glycerin, which suit oily, acne-prone, and sensitive skin. In contrast, the Spanish brand, founded in 1989, is known for advanced serums and precise formulations that best address sensitive, hyperpigmented, and aging complexions. Ultimately, Simple focuses on comforting hydration and barrier support, while Sesderma utilizes specialized active compounds and botanical extracts to refine skin texture and promote radiance.
Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.
en.wikipedia.orgsec.govprnewswire.comsimple.co.uk
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Simple and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Questions and answers
Simple or Sesderma: which is better?
Simple is a better fit for shoppers looking for fragrance-free, budget-friendly cleansers and moisturizers, whereas the products on this page for Sesderma include fragrance. Niacinamide helps reduce skin pigmentation.
What is the difference between Simple and Sesderma?
Simple offers a wider range of fragrance-free cleansers, makeup removers, and moisturizers featuring ingredients like niacinamide, whereas Sesderma features a single serum with fragrance. Niacinamide helps reduce pigmentation.
Which is more affordable, Simple or Sesderma?
Simple stands out for being more affordable, as reviewers frequently mention its moisturizers are value-friendly. In comparison, the Sesderma products on this page do not feature affordability highlights.
Which causes fewer breakouts, Simple or Sesderma?
Simple helps sensitive and acne-prone skin with fragrance-free formulas, though reviewers note that some products may still cause occasional breakouts or irritation.
Which brand offers a higher fit level for sensitive skin, Simple or Sesderma?
Simple offers a higher fit level for sensitive skin, with a High fit for its Kind to Skin Soothing Facial Toner and High fits for its micellar waters, compared to a lower Average fit from Sesderma's Azelac RU Serum.
Do products from Simple or Sesderma contain fragrance?
Simple products on this page list no fragrance in their ingredients, whereas the Azelac RU Serum from Sesderma contains fragrance. Every Simple item avoids added scent, helping shoppers who prefer fragrance-free options.
When was Simple founded compared to Sesderma?
Simple was founded in 1960 in the United Kingdom, whereas Sesderma was founded later in 1989 in Spain.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis
Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.
