Simple vs Sesderma
Simple and Sesderma are distinguished skincare brands offering distinct approaches to daily routines, with the former providing gentle moisturizers, makeup removers, cleansers, and toners featuring niacinamide and glycerin, and the latter known for advanced serums and meticulously engineered formulas. The British brand suits oily and acne-prone skin best through thoughtful formulations like the Kind to Skin Soothing Facial Toner, Micellar Cleansing Water, and standard Micellar Water, whereas the Spanish brand excels for sensitive, hyperpigmented, and aging skin with standout options such as the Azelac RU Serum. While both utilize synergistic active ingredients to refine skin texture, promote a radiant complexion, and improve hydration, they ultimately differ in their formulation philosophy and targeted concerns.
Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.
en.wikipedia.orgsec.govprnewswire.comsimple.co.uk
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Simple and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Questions and answers
Simple or Sesderma: which is better?
Simple offers more products on this page and is rated High for sensitive skin, while the products on this page help reduce skin pigmentation.
What is the difference between Simple and Sesderma?
Simple offers a wide range of fragrance-free cleansers, moisturizers, and makeup removers that Lovi rates as having a High fit for sensitive skin, while Sesderma features targeted treatments like the Azelac RU Serum that contains fragrance and achieves a High fit for skin with dark spots and acne-prone skin.
Which is more affordable, Simple or Sesderma?
Simple offers value-friendly moisturizers, making the products on this page more affordable than Sesderma.
Which causes fewer breakouts, Simple or Sesderma?
Simple features fragrance-free products on this page and is known for gentle makeup removers, but reviewers mention that the products on this page still may cause breakouts or irritations.
Which brand offers fragrance-free products according to the page?
Simple offers fragrance-free products, as every product on the page lists no fragrance in its ingredients.
How do the origins and founding years of Simple and Sesderma compare?
Simple was founded in the United Kingdom in 1960, whereas Sesderma was founded in Spain in 1989.
What are the skin types that Simple fits best based on its brand-focused routines?
Based on its brand-focused routines, Simple fits oily skin, acne-prone skin, and sensitive skin best.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis
Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.
