Simple vs Sesderma
Simple and Sesderma are distinguished skincare brands offering distinct approaches to daily routines, with the former providing gentle moisturizers, makeup removers, cleansers, and toners featuring niacinamide and glycerin, and the latter known for advanced serums and meticulously engineered formulas. The British brand suits oily and acne-prone skin best through thoughtful formulations like the Kind to Skin Soothing Facial Toner, Micellar Cleansing Water, and standard Micellar Water, whereas the Spanish brand excels for sensitive, hyperpigmented, and aging skin with standout options such as the Azelac RU Serum. While both utilize synergistic active ingredients to refine skin texture, promote a radiant complexion, and improve hydration, they ultimately differ in their formulation philosophy and targeted concerns.
Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.
en.wikipedia.orgsec.govprnewswire.comsimple.co.uk
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Simple and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Questions and answers
Simple or Sesderma: which is better?
Simple offers more product variety and fragrance-free options on this page, while Sesderma features targeted formulas like Azelac RU Serum for hyperpigmentation. Niacinamide helps reduce cutaneous pigmentation. Lovi rates the products on this page across different skin types from Low to Superior.
What is the difference between Simple and Sesderma?
Simple offers a broad range of fragrance-free cleansers, makeup removers, and moisturizers featuring niacinamide and glycerin that fit oily, acne-prone, and mature skin best, whereas Sesderma features a scented serum on this page with high fits for acne-prone skin and dark spots.
Which is more affordable, Simple or Sesderma?
Simple offers more affordable options, particularly known for its value-friendly moisturizers. In contrast, the Sesderma product on this page is a specialized serum.
Which causes fewer breakouts, Simple or Sesderma?
Simple features fragrance-free options that reviewers sometimes note can cause breakouts, while Sesderma has no review data on breakouts for the products on this page.
Which brand has been established longer and where are they from?
Simple has been established longer, having been founded in 1960 in the United Kingdom, whereas Sesderma was founded in 1989 in Spain.
Do any products from Simple or Sesderma contain fragrance?
Simple features no fragrance in every product on this page, whereas Sesderma includes fragrance in its Azelac RU Serum.
How does the Lovi fit level for sensitive skin compare between Simple's Micellar Cleansing Water and Sesderma's Azelac RU Serum?
Simple's Micellar Cleansing Water earns a High Lovi fit level for sensitive skin, whereas Sesderma's Azelac RU Serum reaches an Average fit level. Every product on the Simple page lists no fragrance, while Sesderma's serum includes fragrance.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis
Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.
