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Simple vs Sesderma

Simple and Sesderma are distinguished skincare brands that offer thoughtfully crafted products for diverse complexions. The British brand is known for gentle moisturizers, makeup removers, cleansers, and toners enriched with niacinamide and glycerin, which suit acne-prone and oily skin best. Conversely, the Spanish brand is beloved for advanced serums and meticulously engineered formulas featuring botanical extracts and active compounds that suit sensitive, hyperpigmented, and aging skin types best. These collections differ primarily in their formulation approaches and target concerns, allowing both to address specific needs with precision.

Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.

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Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

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This page compares some of the most popular Simple and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Questions and answers

Simple or Sesderma: which is better?

Simple offers more options with no fragrance listed in its ingredients and fits sensitive skin well, while Sesderma provides targeted treatments like Azelac RU Serum for dark spots.

What is the difference between Simple and Sesderma?

Simple offers a broad range of fragrance-free cleansers, makeup removers, and moisturizers featuring niacinamide and glycerin that best fit acne-prone and oily skin, whereas Sesderma is represented by a single fragranced serum, Azelac RU Serum, which achieves a High fit for acne-prone skin and skin with dark spots.

The British Journal of Dermatology, 2002Antioxidants, 2021

Which is more affordable, Simple or Sesderma?

Simple features lightweight, value-friendly moisturizers, making it the more affordable option compared to Sesderma.

Which causes fewer breakouts, Simple or Sesderma?

Simple features fragrance-free options and is generally well-received for gentle makeup removal, but reviewers note that the products on this page often cause breakouts or irritations.

When and where were Simple and Sesderma founded?

Simple was founded in 1960 in the United Kingdom, while Sesderma was founded in 1989 in Spain.

Do products from Simple or Sesderma contain fragrance?

Every product from Simple lists no fragrance in its ingredients, whereas the Azelac RU Serum from Sesderma contains fragrance.

What are the key ingredients found across Simple products?

Niacinamide and Glycerin are the key ingredients found across the products on this page for Simple. Glycerin helps moisturize the skin.

The British Journal of Dermatology, 2002

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.