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Simple vs Sesderma

Simple and Sesderma are distinguished skincare brands that offer thoughtfully crafted products for diverse complexions. The British brand is known for gentle moisturizers, makeup removers, cleansers, and toners enriched with niacinamide and glycerin, which suit acne-prone and oily skin best. Conversely, the Spanish brand is beloved for advanced serums and meticulously engineered formulas featuring botanical extracts and active compounds that suit sensitive, hyperpigmented, and aging skin types best. These collections differ primarily in their formulation approaches and target concerns, allowing both to address specific needs with precision.

Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.

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Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

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This page compares some of the most popular Simple and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Questions and answers

Simple or Sesderma: which is better?

Simple is the better choice for shoppers seeking fragrance-free, budget-friendly everyday cleansers and makeup removers, whereas Sesderma offers a specialized serum for dark spots and acne-prone skin. Niacinamide helps reduce skin pigmentation, and glycerin helps keep skin hydrated.

The British Journal of Dermatology, 2002Antioxidants, 2021

What is the difference between Simple and Sesderma?

Simple offers a broad range of fragrance-free cleansers, moisturizers, and makeup removers that fit acne-prone, oily, and sensitive skin best, while Sesderma features a single serum for dark spots and acne-prone skin that includes fragrance. Niacinamide helps reduce pigmentation and control skin aging in products from both brands.

The British Journal of Dermatology, 2002Antioxidants, 2021

Which is more affordable, Simple or Sesderma?

Simple offers lightweight, value-friendly moisturizers, making the products on this page a more affordable choice compared to Sesderma.

Which causes fewer breakouts, Simple or Sesderma?

Simple offers fragrance-free products on this page, but reviewers often mention that some items may cause breakouts or irritations. Sesderma's serum contains fragrance, though azelaic acid helps manage acne-prone skin.

Pharmaceutics, 2021

How do the founding years and countries of origin compare between Simple and Sesderma?

Simple was founded in 1960 in the United Kingdom, whereas Sesderma was founded in 1989 in Spain.

Which brand offers products with no fragrance, Simple or Sesderma?

Simple offers products with no fragrance, as every product on this page lists no fragrance in its ingredients. In contrast, Azelac RU Serum by Sesderma includes fragrance.

What key ingredients are found across Simple products?

Simple products feature niacinamide and glycerin as key ingredients across the range. Niacinamide helps reduce skin pigmentation and controls skin aging.

The British Journal of Dermatology, 2002Antioxidants, 2021

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.