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Simple vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Simple and Sesderma are distinguished skincare brands offering distinct approaches to daily routines, with the former providing gentle moisturizers, makeup removers, cleansers, and toners featuring niacinamide and glycerin, and the latter known for advanced serums and meticulously engineered formulas. The British brand suits oily and acne-prone skin best through thoughtful formulations like the Kind to Skin Soothing Facial Toner, Micellar Cleansing Water, and standard Micellar Water, whereas the Spanish brand excels for sensitive, hyperpigmented, and aging skin with standout options such as the Azelac RU Serum. While both utilize synergistic active ingredients to refine skin texture, promote a radiant complexion, and improve hydration, they ultimately differ in their formulation philosophy and targeted concerns.

Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.

en.wikipedia.orgsec.govprnewswire.comsimple.co.uk

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Simple and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Simple vs Sesderma products

Questions and answers

Simple or Sesderma: which is better?

Simple offers more options with no fragrance listed and is a better fit for sensitive skin, while the products on this page for Sesderma include fragrance.

What is the difference between Simple and Sesderma?

Simple offers fragrance-free products featuring niacinamide and glycerin that Lovi rates high for sensitive and acne-prone skin, whereas Sesderma includes fragrance in its serum and has lower fit levels for dry skin.

The British Journal of Dermatology, 2002Antioxidants, 2021

Which is more affordable, Simple or Sesderma?

Simple offers lightweight, value-friendly moisturizers, while Sesderma is represented by a single specialty serum on this page.

Which causes fewer breakouts, Simple or Sesderma?

Simple features fragrance-free products on this page, but reviewers often note that the products on this page may cause breakouts or irritations.

Which brand has been established longer, Simple or Sesderma?

Simple has been established longer, having been founded in the United Kingdom in 1960, whereas Sesderma was founded in Spain in 1989.

Do products from Simple or Sesderma contain fragrance?

Every product on this page from Simple lists no fragrance in its ingredients, whereas the Azelac RU Serum from Sesderma contains fragrance.

Which brand offers more product options on the comparison page?

Simple offers more product options on this page, featuring seven items compared to just one from Sesderma.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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