Anua Niacinamide 10% + TXA 4% Serum for mature skin
Niacinamide
Txa Tranexamic Acid
Hyaluronic Acid
Panthenol
AllantoinHigh
- HighNormal Skin Fit
- HighEffectiveness
- HighSafety
A great choice for mature skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers high suitability for your normal skin due to the presence of niacinamide and glycerin, which provide humectant action and seboregulation, addressing your concerns about wrinkles and fine lines by improving skin texture.
- The serum also contains hyaluronic acid, which further enhances hydration and contributes to a smoother appearance, complementing the niacinamide's brightening effects.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of prohibited or harsh ingredients.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
People Say
★4.6Overall rating based on 2.5k+ reviewsBased on a very large amount of data, this serum is highly effective at fading post-acne marks and evening out skin tone, with many users reporting a radiant glow within weeks. While generally well-tolerated and hydrating for many, a significant number of users find the serum leaves a sticky residue, and a smaller portion experience breakouts or irritation, possibly due to the high niacinamide concentration.
Highlights
Fades dark spots Mostly Mentioned
- “Significant reduction in hyperpigmentation from acne scarring.”
- “Fades my dark spots so well... noticed a brightening effect within two-three weeks.”
- “Helped fade my postpartum spots!”
- “Getting rid of acne marks on my face.”
Brightens skin Often Mentioned
- “Gives my skin a beautiful, healthy glow.”
- “My face visibly brighten[ed].”
- “Skin looks healthier and brighter.”
- “Wake up to a brighter skin.”
Sticky finish Often Mentioned
- “Left such a gross tacky finish that refused to dry.”
- “Serum is so sticky... even if I use a tiny drop.”
- “Feels sticky to me.”
- “Has a slightly tacky finish to it.”
Hydrating Sometimes Noted
- “Sinks right into my skin.”
- “Feels quite hydrating... tightness disappears.”
- “Doesn't clash with other parts of my routine.”
- “Leaves skin silky-smooth.”
Improves texture Sometimes Noted
- “Reduction in texture from acne scarring.”
- “Skin feels plump and bouncy.”
- “Smoothing out small bumps.”
- “Pore minimization, skin tightening.”
Caused breakouts Sometimes Noted
- “Broke me out.”
- “My forehead is full [of] acne.”
- “Caused tiny bumps/whiteheads.”
- “Started getting acne... not sure if it's because of this.”
Caused irritation Rarely Noted
- “Irritated my skin at first.”
- “Might be irritating to some skin types.”
- “Stinging sensation upon application.”
- “Too strong for sensitive skin.”
Slow results Rarely Noted
- “Did nothing for my skin.”
- “Haven't noticed much of a difference.”
- “Not as fast as [I] want it to be.”
- “Saw very minimal results.”
Sources: lovi.care, oliveyoung.com, yesstyle.com, stylevana.com, reddit.com, skinsort.com, and more
Questions and answers
What makes Anua Niacinamide 10% + TXA 4% Serum a great fit for mature skin?
This serum is a great fit for mature skin because it features niacinamide and glycerin to smooth out fine lines and wrinkles while keeping skin texture soft. It also has hyaluronic acid to boost hydration for a more plump, smooth look, and it is very safe and gentle to use.
Journal of Cosmetic Dermatology, 2021Dermatologic Therapy, 2022
Which ingredients make this serum a good fit for mature skin?
This serum is a great fit for mature skin because it contains niacinamide and hyaluronic acid, which help smooth out fine lines and wrinkles while boosting hydration. Glycerin also helps keep the skin soft and comfortable.
Journal of Cosmetic Dermatology, 2021Dermatologic Therapy, 2022
What does Niacinamide do for mature skin?
Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
What does Tranexamic Acid do for mature skin?
Tranexamic acid helps reduce brown spots and uneven tone while improving overall skin brightness. Studies show that using it regularly can fade stubborn pigmentation safely and with very little irritation.
Journal of Cosmetic Dermatology, 2024Journal of Cosmetic Science, 2020
Where does this serum go in a skincare routine for mature skin?
This treatment serum goes in the evening routine after cleansing and toning, and before moisturizing. It is unlikely to cause irritation on mature skin, helping to smooth fine lines and boost hydration safely.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol by applying the serum first to help smooth and hydrate mature skin, followed by your retinol. This approach is unlikely to cause irritation because the formula has a very safe profile without harsh ingredients.
Journal of Cosmetic Dermatology, 2021The British Journal of Dermatology, 2002
How often should I use this serum?
Use this serum in the evening as part of your routine. It has a very safe profile and is unlikely to cause irritation on normal skin, helping to smooth out fine lines and brighten your tone over time.
Facial Plastic Surgery, 2014Journal of Cosmetic Dermatology, 2021
Can this serum clog pores, cause breakouts or purging for mature skin?
This serum is unlikely to cause irritation for your mature skin due to the absence of harsh ingredients, though a moderate number of reviewers report breakouts. It helps smooth lines and hydrate dry areas without heavy oils that typically clog pores.
Journal of Cosmetic Dermatology, 2021Dermatologic Therapy, 2022
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.
The British Journal of Dermatology, 2002Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.
Dermatologic Therapy, 2022Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline.
Journal of Cosmetic and Laser Therapy, 2006Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.
Arzneimittel-Forschung, 2000Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.
Auris, Nasus, Larynx, 2020Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.
Aesthetic Plastic Surgery, 2018
Ingredients
Water, Niacinamide, Glycerin, Butylene Glycol, 1,2-Hexanediol, Betaine, Panthenol, Hyaluronic Acid, Allantoin, Tocopherol, Ethylhexylglycerin, Xanthan Gum, Disodium Edta
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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