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Neutrogena vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Neutrogena and Sesderma are trusted skincare brands that offer reliable daily care for diverse complexions. The American brand, founded in 1930, is widely loved for its thoughtful array of moisturizers, sunscreens, cleansers, toners, and more, which rely on trusted ingredients like glycerin, hyaluronic acid, and dimethicone. Meanwhile, the Spanish brand, founded in 1989, is beloved for its advanced serums and meticulously engineered formulas, featuring botanical extracts and active compounds that work synergistically. While the first suits dry skin and mature skin best through moisture-binding and barrier-supporting formulas, the second suits sensitive, hyperpigmented, and aging skin types best to refine texture and promote a radiant complexion.

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Neutrogena and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Neutrogena vs Sesderma products

Questions and answers

Neutrogena or Sesderma: which is better?

Neutrogena is the better choice on this page due to offering a much wider variety of products tailored for dry, mature, and acne-prone skin types, whereas Sesderma lists only a single serum. Furthermore, Neutrogena products on this page frequently feature hydrating ingredients like hyaluronic acid, which helps improve skin moisture levels.

Journal of Pharmacy & Pharmaceutical Sciences, 2015Dermatologic Therapy, 2022

What is the difference between Neutrogena and Sesderma?

Neutrogena is a much larger United States brand founded in 1930 that offers a wide variety of cleansers, sunscreens, and moisturizers on this page, whereas Sesderma is a Spanish brand founded in 1989 that currently features only one product.

Which is more affordable, Neutrogena or Sesderma?

The provided page facts do not contain pricing information, so a comparison of affordability between Neutrogena and Sesderma cannot be made from this page.

Which causes fewer breakouts, Neutrogena or Sesderma?

Neutrogena has many products on this page with a High or Superior Lovi fit level for acne-prone skin, whereas Sesderma only features Azelac RU Serum, which has a High fit level for acne-prone skin. Neutrogena offers a wider variety of options tailored to help prevent breakouts.

Which brand offers more products for dry skin, Neutrogena or Sesderma?

Neutrogena offers far more products for dry skin than Sesderma on this page. The products on this page for Neutrogena include multiple moisturizers and cleansers rated for dry skin, whereas Sesderma is represented by a single serum that has a low fit level for dry skin.

How does the country of origin differ between Neutrogena and Sesderma?

Neutrogena was founded in the United States in 1930, whereas Sesderma was founded in Spain in 1989.

Which brand has a higher percentage of fragrance-free products?

Neutrogena has a much higher percentage of fragrance-free products, with 35 out of 39 products on this page listing no fragrance. In contrast, Sesderma includes fragrance in its only product listed on the page.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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