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Neutrogena vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Neutrogena and Sesderma are trusted skincare brands that offer reliable daily care for diverse complexions. The American brand is widely loved for its thoughtfully formulated moisturizers, sunscreens, cleansers, and toners featuring glycerin, hyaluronic acid, and dimethicone, which suit mature skin and skin with dark spots best. Meanwhile, the Spanish brand is beloved for advanced serums and meticulously engineered formulas that suit sensitive, hyperpigmented, and aging skin types best. While both brands support healthier skin through active components, they differ in their origin, founding eras, and specific formulations.

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Neutrogena and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Neutrogena vs Sesderma products

Questions and answers

Neutrogena or Sesderma: which is better?

Neutrogena offers a much wider variety of products across multiple skincare categories on this page, while Sesderma features only a single serum. Neutrogena products on this page frequently help with hydration, anti-aging, and acne, backed by ingredients like retinol and hyaluronic acid.

The Journal of Investigative Dermatology, 2000Journal of Pharmacy & Pharmaceutical Sciences, 2015

What is the difference between Neutrogena and Sesderma?

Neutrogena offers a large range of 39 products on this page spanning cleansers, moisturizers, and sunscreens that mostly avoid fragrance, whereas Sesderma is represented by a single fragranced serum. Neutrogena features high Lovi fit levels for mature skin, acne-prone skin, and skin with dark spots, while the products on this page from Sesderma achieve high Lovi fit for acne-prone skin and skin with dark spots.

Which is more affordable, Neutrogena or Sesderma?

This page does not provide pricing information or price comparisons between Neutrogena and Sesderma.

Which causes fewer breakouts, Neutrogena or Sesderma?

Neutrogena has a much wider range of products on this page with high or superior Lovi fit levels for acne-prone skin, such as its daily cleanser and various treatments, whereas Sesderma only features one serum.

Between Neutrogena and Sesderma, which brand was founded earlier and in which countries?

Neutrogena was founded earlier in 1930 in the United States, while Sesderma was founded in 1989 in Spain.

How do the fragrance options compare between Neutrogena and Sesderma products listed on the page?

Neutrogena offers mostly fragrance-free products on this page, whereas Sesderma includes fragrance in its listed item. Specifically, thirty-five of the thirty-nine Neutrogena products list no fragrance.

What specific Lovi fit level does Sesderma's Azelac RU Serum have for acne-prone skin compared to Neutrogena's anti-acne offerings?

Sesderma's Azelac RU Serum has a High Lovi fit level for acne-prone skin. Neutrogena offers various anti-acne products on this page with fit levels ranging from Superior to Average.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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