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Neutrogena vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Neutrogena and Sesderma are trusted skincare brands that offer reliable daily care for diverse complexions. The American brand, founded in 1930, is widely loved for its thoughtful array of moisturizers, sunscreens, cleansers, toners, and more, which rely on trusted ingredients like glycerin, hyaluronic acid, and dimethicone. Meanwhile, the Spanish brand, founded in 1989, is beloved for its advanced serums and meticulously engineered formulas, featuring botanical extracts and active compounds that work synergistically. While the first suits dry skin and mature skin best through moisture-binding and barrier-supporting formulas, the second suits sensitive, hyperpigmented, and aging skin types best to refine texture and promote a radiant complexion.

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Neutrogena and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Neutrogena vs Sesderma products

Questions and answers

Neutrogena or Sesderma: which is better?

Neutrogena offers a much wider variety of products on this page than Sesderma, with deep hydration and anti-aging options that generally achieve Average to Superior Lovi fit levels across multiple skin types. Hyaluronic acid helps improve skin moisture and wound healing.

Journal of Pharmacy & Pharmaceutical Sciences, 2015Dermatologic Therapy, 2022

What is the difference between Neutrogena and Sesderma?

Neutrogena offers a wide range of 39 skincare products focused on dry, mature, and sensitive skin, while Sesderma is represented by only one product on this page, the Azelac RU Serum, which has a High fit for acne-prone skin and skin with dark spots.

Which is more affordable, Neutrogena or Sesderma?

The products on this page do not provide pricing information to compare affordability between Neutrogena and Sesderma.

Which causes fewer breakouts, Neutrogena or Sesderma?

Neutrogena has several products on this page with a Superior or High Lovi fit level for acne-prone skin, such as its Ultra Gentle Daily Cleanser and Daily Facial Moisturizer. Sesderma features just one product on this page, Azelac RU Serum, which has a High Lovi fit level for acne-prone skin.

Which brand has more fragrance-free product options, Neutrogena or Sesderma?

Neutrogena has significantly more fragrance-free product options than Sesderma, with 35 of its 39 products on this page listing no fragrance. In contrast, the single Sesderma product on this page includes fragrance.

Where and when were Neutrogena and Sesderma founded, and who owns them?

Neutrogena was founded in 1930 in the United States and is owned by Kimberly-Clark Corporation, while Sesderma was founded in 1989 in Spain and is owned by Grupo Sesderma.

Which brand offers a wider variety of skincare products on this page, Neutrogena or Sesderma?

Neutrogena offers a much wider variety of skincare products on this page, featuring dozens of items across categories like cleansers, sunscreens, and moisturizers. In contrast, Sesderma is represented by only a single serum.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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