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Neutrogena vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Neutrogena and Sesderma are trusted skincare brands that offer reliable daily care for diverse complexions. The American brand, founded in 1930, is widely loved for its thoughtful array of moisturizers, sunscreens, cleansers, toners, and more, which rely on trusted ingredients like glycerin, hyaluronic acid, and dimethicone. Meanwhile, the Spanish brand, founded in 1989, is beloved for its advanced serums and meticulously engineered formulas, featuring botanical extracts and active compounds that work synergistically. While the first suits dry skin and mature skin best through moisture-binding and barrier-supporting formulas, the second suits sensitive, hyperpigmented, and aging skin types best to refine texture and promote a radiant complexion.

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Neutrogena and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Neutrogena vs Sesderma products

Questions and answers

Neutrogena or Sesderma: which is better?

Neutrogena is the better choice for most shoppers on this page because it offers a wide range of products with Superior and High fit levels across multiple skin types, whereas Sesderma features only one product here. Neutrogena includes key ingredients like hyaluronic acid and retinol, which help improve skin hydration and reduce signs of aging.

Journal of Pharmacy & Pharmaceutical Sciences, 2015Archives of Dermatology, 2007

What is the difference between Neutrogena and Sesderma?

Neutrogena is an American brand founded in 1930 featuring a wide range of products that on this page fit dry, mature, and sensitive skin best, whereas Sesderma is a Spanish brand founded in 1989 with only one product listed here. Neutrogena offers both fragrance-free and fragranced options, while Sesderma's sole product includes fragrance.

Which is more affordable, Neutrogena or Sesderma?

The products on this page for Neutrogena and Sesderma do not include pricing information, so affordability cannot be compared here.

Which causes fewer breakouts, Neutrogena or Sesderma?

Neutrogena offers several products on this page with High or Superior Lovi fit levels for acne-prone skin, whereas Sesderma has only one product on the page which achieves a High fit level for acne-prone skin.

How do the founding years and countries of origin compare between Neutrogena and Sesderma?

Neutrogena was founded in the United States in 1930, whereas Sesderma was founded in Spain in 1989.

Which brand offers more fragrance-free skincare options based on the available products?

Neutrogena offers far more fragrance-free skincare options, with 35 out of 39 products on this page listing no fragrance. In contrast, Sesderma features only one product on this page, and it contains fragrance.

What are some of the key ingredients shared across the products of these two brands?

Neutrogena and Sesderma share key ingredients like glycerin, hyaluronic acid, and vitamin C across their product lines. Hyaluronic acid helps maintain skin hydration, while vitamin C and retinol may improve signs of aging and dark spots.

The Journal of Investigative Dermatology, 2000

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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