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Neutrogena vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Neutrogena and Sesderma are trusted skincare brands that offer reliable daily care for diverse complexions. The American brand is widely loved for its thoughtfully formulated moisturizers, sunscreens, cleansers, and toners featuring glycerin, hyaluronic acid, and dimethicone, which suit mature skin and skin with dark spots best. Meanwhile, the Spanish brand is beloved for advanced serums and meticulously engineered formulas that suit sensitive, hyperpigmented, and aging skin types best. While both brands support healthier skin through active components, they differ in their origin, founding eras, and specific formulations.

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Neutrogena and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Neutrogena vs Sesderma products

Questions and answers

Neutrogena or Sesderma: which is better?

Neutrogena is better for most shoppers because the products on this page offer a much wider selection across various skin types, featuring deeply hydrating and lightweight moisturizers. Sesderma only provides a single serum on this page, making Neutrogena the more versatile choice.

What is the difference between Neutrogena and Sesderma?

Neutrogena is an American brand founded in 1930 featuring a wide range of moisturizers, sunscreens, and cleansers, whereas Sesderma is a Spanish brand founded in 1989 with a single product listed on this page.

Which is more affordable, Neutrogena or Sesderma?

The products on this page do not provide pricing information to determine which brand is more affordable.

Which causes fewer breakouts, Neutrogena or Sesderma?

Neutrogena has a much wider variety of acne-fighting products on this page, and several options like the Clear Pore Cleanser/Mask achieve a High Lovi fit for acne-prone skin. By comparison, Sesderma features only one product on the page, the Azelac RU Serum, which also achieves a High Lovi fit for acne-prone skin.

Between Neutrogena and Sesderma, which brand was founded earlier and in what countries?

Neutrogena was founded earlier in 1930 in the United States, while Sesderma was founded in 1989 in Spain.

How do the fragrance profiles of Neutrogena and Sesderma products compare based on the page data?

Neutrogena offers mostly fragrance-free products on this page, whereas Sesderma includes fragrance in its listed item. Specifically, thirty-five out of thirty-nine Neutrogena products list no fragrance, while the single Sesderma product contains it.

Which brand offers a serum suitable for acne-prone skin and skin with dark spots like the Azelac RU Serum?

Neutrogena offers several serums suitable for acne-prone skin and skin with dark spots, such as the Stubborn Marks PM Treatment and Rapid Clear Treatment Pads. Lovi rates the Stubborn Marks PM Treatment as High for both acne-prone skin and skin with dark spots.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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