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Neutrogena vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Neutrogena and Sesderma are trusted skincare brands that offer reliable daily care for diverse complexions. The American brand, founded in 1930, is widely loved for its thoughtful array of moisturizers, sunscreens, cleansers, toners, and more, which rely on trusted ingredients like glycerin, hyaluronic acid, and dimethicone. Meanwhile, the Spanish brand, founded in 1989, is beloved for its advanced serums and meticulously engineered formulas, featuring botanical extracts and active compounds that work synergistically. While the first suits dry skin and mature skin best through moisture-binding and barrier-supporting formulas, the second suits sensitive, hyperpigmented, and aging skin types best to refine texture and promote a radiant complexion.

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Neutrogena and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Neutrogena vs Sesderma products

Questions and answers

Neutrogena or Sesderma: which is better?

Neutrogena has a much broader lineup of products on this page compared to Sesderma, which only lists a single item. Neutrogena fits dry skin, mature skin, and acne-prone skin best based on its routines.

What is the difference between Neutrogena and Sesderma?

Neutrogena is a much larger American brand founded in 1930 featuring a wide variety of cleansers, sunscreens, and moisturizers with mostly fragrance-free formulas, whereas Sesderma is a Spanish brand founded in 1989 with only one serum listed on this page that contains fragrance.

Which is more affordable, Neutrogena or Sesderma?

The products on this page do not provide pricing information to determine which brand is more affordable.

Which causes fewer breakouts, Neutrogena or Sesderma?

Neutrogena offers several products that achieve a Superior or High fit for acne-prone skin, whereas the single Sesderma product on this page achieves a High fit. Neutrogena helps manage breakouts with formulas containing salicylic acid and niacinamide, and retinol may help improve skin texture over time.

The Journal of Investigative Dermatology, 2000The British Journal of Dermatology, 2002

Between Neutrogena and Sesderma, which brand was founded earlier and in which countries were they established?

Neutrogena was founded earlier in 1930 in the United States, whereas Sesderma was established later in 1989 in Spain.

How do the fragrance-free product ratios compare between Neutrogena and Sesderma based on the available page data?

Neutrogena has a significantly higher proportion of fragrance-free options, as 35 of its 39 products on this page list no fragrance. In contrast, Sesderma offers only a single product on this page, and it includes fragrance.

Which brand offers a larger variety of skincare products listed on the page for acne-prone and mature skin types?

Neutrogena offers a much larger variety of skincare products on this page for acne-prone and mature skin types compared to Sesderma. The products on this page for Neutrogena include numerous options with High or Superior Lovi fit levels for both skin types, while Sesderma only lists a single product.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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