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Neutrogena vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Neutrogena and Sesderma are distinguished skincare brands that cater to distinct dermatological needs through specialized formulations. The American heritage label offers reliable moisturizers, sunscreens, cleansers, and toners featuring glycerin, hyaluronic acid, and dimethicone, which suit oily acne-prone skin and acne-prone skin best. Meanwhile, the Spanish counterpart is beloved for its advanced serums and meticulously engineered botanical formulas that ideally suit sensitive, hyperpigmented, and aging skin types. While both brands deliver targeted care, they differ primarily in their core active ingredients and the specific skin concerns they address most effectively.

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Neutrogena and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Neutrogena vs Sesderma products

Questions and answers

Neutrogena or Sesderma: which is better?

Neutrogena offers a much wider variety of skincare products on this page compared to Sesderma, which only features a single serum. Neutrogena is rated as an average to superior fit for multiple skin types, while reviewers frequently note its deeply hydrating and lightweight moisturizers.

What is the difference between Neutrogena and Sesderma?

Neutrogena offers a large variety of skincare products on this page that help with acne-prone and mature skin, while Sesderma provides just one serum. Neutrogena features many fragrance-free items and key ingredients like hyaluronic acid and retinol.

The Journal of Investigative Dermatology, 2000Journal of Pharmacy & Pharmaceutical Sciences, 2015

Which is more affordable, Neutrogena or Sesderma?

This page does not contain pricing information to compare the affordability of Neutrogena and Sesderma.

Which causes fewer breakouts, Neutrogena or Sesderma?

Neutrogena has many products on this page with High or Superior Lovi fit levels for acne-prone skin, whereas Sesderma has only one product on this page, which also has a High fit level for acne-prone skin.

Between Neutrogena and Sesderma, which brand has products formulated with fragrance versus those that list no fragrance?

Neutrogena offers 35 products on this page that list no fragrance alongside 4 products with fragrance, whereas Sesderma features only 1 product on this page, which contains fragrance.

How do the founding years and countries of origin compare between Neutrogena and Sesderma?

Neutrogena was founded in 1930 in the United States, whereas Sesderma was founded in 1989 in Spain.

What are the main key ingredients featured across Neutrogena skincare products?

The products on this page for Neutrogena feature key ingredients such as glycerin, hyaluronic acid, dimethicone, avobenzone, vitamin C, salicylic acid, retinol, and homosalate.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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