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Neutrogena vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Neutrogena and Sesderma are trusted skincare brands that offer reliable daily care for diverse complexions. The American brand, founded in 1930, is widely loved for its thoughtful array of moisturizers, sunscreens, cleansers, toners, and more, which rely on trusted ingredients like glycerin, hyaluronic acid, and dimethicone. Meanwhile, the Spanish brand, founded in 1989, is beloved for its advanced serums and meticulously engineered formulas, featuring botanical extracts and active compounds that work synergistically. While the first suits dry skin and mature skin best through moisture-binding and barrier-supporting formulas, the second suits sensitive, hyperpigmented, and aging skin types best to refine texture and promote a radiant complexion.

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Neutrogena and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Neutrogena vs Sesderma products

Questions and answers

Neutrogena or Sesderma: which is better?

Neutrogena is the better choice for most shoppers because the products on this page offer a wide variety of gentle moisturizers, cleansers, and sunscreens that fit dry, mature, and sensitive skin well. Sesderma only features a single serum on this page, which limits your routine options.

What is the difference between Neutrogena and Sesderma?

Neutrogena offers a wide range of moisturizers, sunscreens, and cleansers that Lovi rates best for dry, mature, and sensitive skin, while Sesderma features just one targeted serum on this page. Neutrogena formulations are largely fragrance-free, whereas the Sesderma product includes fragrance.

Which is more affordable, Neutrogena or Sesderma?

This page does not provide pricing information to compare the affordability of Neutrogena and Sesderma.

Which causes fewer breakouts, Neutrogena or Sesderma?

Neutrogena is a better fit for acne-prone skin, as the products on this page include multiple options with a High or Superior Lovi fit level for acne-prone skin, compared to Sesderma's Azelac RU Serum which has a High fit level.

Between Neutrogena and Sesderma, which brand was founded earlier and in which countries?

Neutrogena was founded earlier in the United States in 1930, while Sesderma was founded in Spain in 1989.

How many products from Neutrogena contain fragrance compared to Sesderma?

Neutrogena has 4 products on this page with fragrance, while Sesderma has 1.

Which key skincare ingredients are found across the products listed for these brands?

Neutrogena features key ingredients such as glycerin, hyaluronic acid, dimethicone, avobenzone, vitamin C, salicylic acid, retinol, and homosalate across the products on this page.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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