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Avène vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Avène and Sesderma are trusted European skincare houses founded in 1990 and 1989 respectively. The French brand is universally loved for its versatile moisturizers, reliable sunscreens, targeted serums, and gentle cleansers, all formulated with nourishing glycerin that improves skin hydration and restores barrier function. Meanwhile, the Spanish brand is beloved for its advanced serums and meticulously engineered formulas, featuring botanical extracts and active compounds that work synergistically to refine skin texture and promote a radiant complexion. While Avène suits acne-prone and oily acne-prone skin best through products like the Tolerance Control Soothing Skin Recovery Balm, Cleanance, and the Hyaluron Activ B3 Concentrated Plumping Serum, Sesderma suits sensitive, hyperpigmented, and aging skin types best with standout options like the Azelac RU Serum.

Avène is a French skincare brand founded in 1990 and owned by Fondation Pierre Fabre.

pierre-fabre.comavene.co.ukaveneusa.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Avène and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Avène vs Sesderma products

Questions and answers

Avène or Sesderma: which is better?

Avène is better suited for a wider variety of skin concerns, as the products on this page offer extensive options for dry, sensitive, and oily skin with key ingredients like glycerin and thermal water. Sesderma has a much smaller selection on this page, represented solely by Azelac RU Serum.

What is the difference between Avène and Sesderma?

Avène is a French brand founded in 1990 with fifteen products on this page, whereas Sesderma is a Spanish brand founded in 1989 with only one product on this page, the Azelac RU Serum. Avène features a wide variety of cleansers, moisturizers, sunscreens, and serums with varying Lovi fit levels across skin types.

Which is more affordable, Avène or Sesderma?

Reviewers note that price point is sometimes a concern for Avene, while the provided facts do not contain pricing information to compare Avene and Sesderma on affordability.

Which causes fewer breakouts, Avène or Sesderma?

For breakout-prone skin, Avène offers multiple products with a High Lovi fit on this page, whereas Sesderma features just one product with a High fit for acne-prone skin. Avène products on this page also help soothe irritation and provide effective oil control.

How does the country of origin and founding year compare between Avène and Sesderma?

Avène was founded in France in 1990, while Sesderma was founded in Spain in 1989.

Which brand offers more fragrance-free products according to the page data?

Avène offers more fragrance-free products on this page, with seven out of its fifteen products listing no fragrance. In contrast, Sesderma has no fragrance-free options listed.

What are the main skin types that Avène's brand-focused routines are designed to fit best?

The products on this page for Avène are designed to fit acne-prone skin, oily acne-prone skin, and combination skin best.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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