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Avène vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Avène and Sesderma are trusted European skincare houses founded in 1990 and 1989 respectively. The French brand is universally loved for its versatile moisturizers, reliable sunscreens, targeted serums, and gentle cleansers, all formulated with nourishing glycerin that improves skin hydration and restores barrier function. Meanwhile, the Spanish brand is beloved for its advanced serums and meticulously engineered formulas, featuring botanical extracts and active compounds that work synergistically to refine skin texture and promote a radiant complexion. While Avène suits acne-prone and oily acne-prone skin best through products like the Tolerance Control Soothing Skin Recovery Balm, Cleanance, and the Hyaluron Activ B3 Concentrated Plumping Serum, Sesderma suits sensitive, hyperpigmented, and aging skin types best with standout options like the Azelac RU Serum.

Avène is a French skincare brand founded in 1990 and owned by Fondation Pierre Fabre.

pierre-fabre.comavene.co.ukaveneusa.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Avène and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Avène vs Sesderma products

Questions and answers

Avène or Sesderma: which is better?

Avène is better suited for most shoppers because the products on this page cover a wide variety of skincare needs, whereas Sesderma only features one product.

What is the difference between Avène and Sesderma?

Avène offers a broad range of products with various Lovi fit levels across multiple skin types, while the products on this page for Sesderma include only Azelac RU Serum. Avène features options for sensitive and dry skin such as Tolerance Control Soothing Skin Recovery Balm, which has a Superior Lovi fit for dry skin, whereas Sesderma focuses on specific treatments like acne-prone skin and dark spots.

Which is more affordable, Avène or Sesderma?

Reviewers note that the price point for Avène products is sometimes mentioned, while the provided page does not contain pricing information for Sesderma to make a comparison.

Which causes fewer breakouts, Avène or Sesderma?

Avène helps control breakouts because the products on this page best fit acne-prone, oily, and oily acne-prone skin, while Sesderma is represented by only one serum that has a high fit for acne-prone skin.

How does the founding year and country of origin compare between Avène and Sesderma?

Avène was founded in France in 1990, while Sesderma was founded in Spain in 1989.

Which brand offers a greater variety of products on this page, Avène or Sesderma?

Avène offers a greater variety of products on this page with fifteen options, whereas Sesderma features only one.

How do the fragrance-free options compare between Avène and Sesderma products?

Avene offers many fragrance-free options, with 7 of its 15 products on this page listing no fragrance, while Sesderma has no fragrance-free options as its single product on this page includes fragrance.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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