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Avène vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Avène and Sesderma are trusted European skincare houses founded in 1990 and 1989 respectively. The French brand is universally loved for its versatile moisturizers, reliable sunscreens, targeted serums, and gentle cleansers, all formulated with nourishing glycerin that improves skin hydration and restores barrier function. Meanwhile, the Spanish brand is beloved for its advanced serums and meticulously engineered formulas, featuring botanical extracts and active compounds that work synergistically to refine skin texture and promote a radiant complexion. While Avène suits acne-prone and oily acne-prone skin best through products like the Tolerance Control Soothing Skin Recovery Balm, Cleanance, and the Hyaluron Activ B3 Concentrated Plumping Serum, Sesderma suits sensitive, hyperpigmented, and aging skin types best with standout options like the Azelac RU Serum.

Avène is a French skincare brand founded in 1990 and owned by Fondation Pierre Fabre.

pierre-fabre.comavene.co.ukaveneusa.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Avène and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Avène vs Sesderma products

Questions and answers

Avène or Sesderma: which is better?

Avène is better suited for a broader range of skin types with fifteen diverse products on this page, whereas Sesderma currently features only one product.

What is the difference between Avène and Sesderma?

Avene offers a much wider variety of skincare products on this page across multiple categories, while Sesderma is represented by a single serum. Avene fits best for acne-prone skin, oily acne-prone skin, and combination skin.

Which is more affordable, Avène or Sesderma?

Reviewers note that the price point is a drawback for Avene, while pricing information for Sesderma is not available on this page.

Which causes fewer breakouts, Avène or Sesderma?

Avène has a wide range of products on this page with High Lovi fit for acne-prone skin, such as Cleanance sunscreen and Cleanance Cleansing Gel, while Sesderma features Azelac RU Serum, which also has a High Lovi fit for acne-prone skin.

Pharmaceutics, 2021

Which brand has been around longer and where were they founded, Avène or Sesderma?

Sesderma has been around slightly longer, having been founded in Spain in 1989, whereas Avène was founded in France in 1990.

How many products are listed for Avène compared to Sesderma, and what are their respective fragrance contents?

Avène has 15 products listed on this page, while Sesderma has 1. For Avène, 7 of the 15 products list no fragrance, whereas Sesderma lists fragrance in its single product.

Which specific serum does Sesderma offer on this page, and what are its fit levels for acne-prone and dry skin?

Sesderma offers the Azelac RU Serum on this page. Lovi rates its fit as High for acne-prone skin and Low for dry skin.

Pharmaceutics, 2021

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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