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Avène vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Avène and Sesderma are a French brand founded in 1990 and a Spanish brand founded in 1989, respectively. The French brand is loved for its gentle moisturizers, protective sunscreens, targeted serums, and soothing cleansers formulated with glycerin, suiting oily acne-prone skin and combination skin best. Conversely, Sesderma is beloved for its advanced serums and meticulously engineered formulas that suit sensitive, hyperpigmented, and aging skin types best. While both brands address acne-prone skin through standout treatments like the Tolerance Control Soothing Skin Recovery Balm, Cleanance, Hyaluron Activ B3 Concentrated Plumping Serum, and Azelac RU Serum, they differ in their foundational ingredients and primary skin type focuses.

Avène is a French skincare brand founded in 1990 and owned by Fondation Pierre Fabre.

pierre-fabre.comavene.co.ukaveneusa.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Avène and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Avène vs Sesderma products

Questions and answers

Avène or Sesderma: which is better?

Avène is better for a wider variety of skin types because the products on this page fit oily acne-prone, combination, and acne-prone skin best, whereas Sesderma has only one product featured.

What is the difference between Avène and Sesderma?

Avene offers a wide variety of fifteen products that fit oily acne-prone, combination, and acne-prone skin best, while Sesderma features just one product on this page, the Azelac RU Serum. Glycerin helps moisturize the skin, and azelaic acid helps manage acne-prone skin.

Pharmaceutics, 2021

Which is more affordable, Avène or Sesderma?

Price point is sometimes noted as a drawback for Avène, while the page provides no pricing details for Sesderma to make a comparison.

Which causes fewer breakouts, Avène or Sesderma?

Avène products on this page have a High Lovi fit for acne-prone and oily acne-prone skin types and help control oil, whereas Sesderma is represented by only one serum with a High fit for acne-prone skin.

How do the founding years and countries of origin compare between Avène and Sesderma?

Avène was founded in 1990 in France, whereas Sesderma was founded in 1989 in Spain.

Which brand offers a wider variety of products listed on the page, and what are their respective categories?

Avène offers a wider variety of products on this page, spanning categories such as cleansers, moisturizers, serums, sunscreens, eye products, masks, and toners. In contrast, Sesderma features only a serum on this page.

How does the fragrance presence differ between Avène products and the Sesderma product listed?

Among the products on this page, Avène features several fragrance-free options with 7 of 15 products listing no fragrance, whereas the Sesderma product contains fragrance.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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