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Avène vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Avène and Sesderma are trusted European skincare houses founded in 1990 and 1989 respectively. The French brand is universally loved for its versatile moisturizers, reliable sunscreens, targeted serums, and gentle cleansers, all formulated with nourishing glycerin that improves skin hydration and restores barrier function. Meanwhile, the Spanish brand is beloved for its advanced serums and meticulously engineered formulas, featuring botanical extracts and active compounds that work synergistically to refine skin texture and promote a radiant complexion. While Avène suits acne-prone and oily acne-prone skin best through products like the Tolerance Control Soothing Skin Recovery Balm, Cleanance, and the Hyaluron Activ B3 Concentrated Plumping Serum, Sesderma suits sensitive, hyperpigmented, and aging skin types best with standout options like the Azelac RU Serum.

Avène is a French skincare brand founded in 1990 and owned by Fondation Pierre Fabre.

pierre-fabre.comavene.co.ukaveneusa.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Avène and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Avène vs Sesderma products

Questions and answers

Avène or Sesderma: which is better?

Avène is better suited for a broader range of skin types, given that the products on this page cover multiple cleansers, moisturizers, and sunscreens with high Lovi fit levels for dry and sensitive skin. Sesderma is represented by only one product on this page, which may help with acne-prone skin and dark spots but offers fewer options.

Pharmaceutics, 2021

What is the difference between Avène and Sesderma?

Avène offers a broad range of 15 products on this page featuring items with Superior Lovi fit for dry and sensitive skin, whereas Sesderma is represented by a single serum focused on acne-prone skin and dark spots. Avène relies heavily on thermal water and glycerin, while the Sesderma product contains fragrance and utilizes azelaic acid.

Pharmaceutics, 2021

Which is more affordable, Avène or Sesderma?

Reviewers note that the price point of Avène is a sometimes noted drawback, while information on the pricing of the products on this page for Sesderma is not available.

Which causes fewer breakouts, Avène or Sesderma?

Avène helps reduce breakouts with products on this page such as its Cleanance sunscreen and cleansing gel achieving High Lovi fit levels for acne-prone skin, whereas Sesderma features only the Azelac RU Serum here. The products on this page help manage blemishes with ingredients like azelaic acid.

Pharmaceutics, 2021

How does the country of origin and founding year compare between Avène and Sesderma?

Avène was founded in France in 1990, whereas Sesderma was founded in Spain in 1989.

Which brand offers more fragrance-free products, Avène or Sesderma?

Avene offers more fragrance-free products than Sesderma, as 7 of the 15 products on the Avene page list no fragrance while Sesderma has none listed without it.

What are the key ingredients featured across Avène's product line?

Thermal water and glycerin are the key ingredients featured across the products on this page for Avène.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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