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Shiseido vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Shiseido and Sesderma are distinguished skincare brands originating from Japan and Spain, respectively. The Japanese house is beloved for its thoughtful array of moisturizers, cleansers, sunscreens, and serums formulated with key ingredients like glycerin, while the Spanish enterprise is known for advanced serums and meticulously engineered formulas featuring botanical extracts and active compounds. Both options suit sensitive skin best, with the former also favoring mature skin and the latter accommodating hyperpigmented and aging skin types. They differ primarily in their heritage and specific active approaches, with standout choices ranging from the Treatment Softener and Benefiance Wrinkle Smoothing Day Cream to the Azelac RU Serum.

Shiseido is a Japanese skincare brand founded in 1872 and owned by Shiseido Company, Limited.

corp.shiseido.comen.wikipedia.orgmarketscreener.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Shiseido and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Shiseido vs Sesderma products

Questions and answers

Shiseido or Sesderma: which is better?

Shiseido is the better choice for shoppers seeking a wide variety of skincare items, as the products on this page offer many options for sensitive and mature skin, while Sesderma features only a single serum. Topical hyaluronic acid helps improve skin quality and signs of aging.

Dermatologic Therapy, 2022

What is the difference between Shiseido and Sesderma?

Shiseido is a Japanese brand founded in 1872 with a wide range of products on this page that fit sensitive and mature skin best, while Sesderma is a Spanish brand founded in 1989 with only one serum listed on this page.

Which is more affordable, Shiseido or Sesderma?

Reviewers note that Shiseido products on this page have a high price point, while pricing information for Sesderma is not mentioned on this page.

Which causes fewer breakouts, Shiseido or Sesderma?

Shiseido includes products on this page rated with a Low or Warning fit for acne-prone skin, while the Azelac RU Serum by Sesderma has a High Lovi fit for acne-prone skin.

Which brand has been around longer, Shiseido or Sesderma?

Shiseido has been around longer, having been founded in Japan in 1872, whereas Sesderma was founded in Spain in 1989.

Do Shiseido and Sesderma products contain fragrance?

Yes, all the products from Sesderma and the vast majority of the products from Shiseido on this page contain fragrance. Specifically, 15 out of 20 Shiseido products list fragrance, and the single Sesderma product also contains fragrance.

Where are Shiseido and Sesderma headquartered?

Shiseido is headquartered in Japan, and Sesderma is headquartered in Spain.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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