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Shiseido vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Shiseido and Sesderma are distinguished skincare brands originating from Japan and Spain, respectively. The Japanese house is beloved for its thoughtful array of moisturizers, cleansers, sunscreens, and serums formulated with key ingredients like glycerin, while the Spanish enterprise is known for advanced serums and meticulously engineered formulas featuring botanical extracts and active compounds. Both options suit sensitive skin best, with the former also favoring mature skin and the latter accommodating hyperpigmented and aging skin types. They differ primarily in their heritage and specific active approaches, with standout choices ranging from the Treatment Softener and Benefiance Wrinkle Smoothing Day Cream to the Azelac RU Serum.

Shiseido is a Japanese skincare brand founded in 1872 and owned by Shiseido Company, Limited.

corp.shiseido.comen.wikipedia.orgmarketscreener.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Shiseido and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Shiseido vs Sesderma products

Questions and answers

Shiseido or Sesderma: which is better?

Shiseido and Sesderma offer very different options on this page, with Shiseido providing a wide range of cleansers, moisturizers, and sunscreens that fit sensitive and mature skin best, while Sesderma features just one specialized serum, the Azelac RU Serum, which has a high fit for acne-prone skin and skin with dark spots.

What is the difference between Shiseido and Sesderma?

Shiseido is a Japanese company founded in 1872 that features a wide range of products on this page best fitting sensitive, mature, and oily skin, whereas Sesderma is a Spanish company founded in 1989 that lists just one serum on this page.

Which is more affordable, Shiseido or Sesderma?

Reviewers frequently note that Shiseido has a high price point, while pricing details for Sesderma are not available on this page.

Which causes fewer breakouts, Shiseido or Sesderma?

The products on this page for Shiseido include options that Lovi rates as High for acne-prone skin, such as Essential Energy Hydrating Cream, while Sesderma offers Azelac RU Serum, which Lovi rates as High for acne-prone skin.

Which brand has been around longer and where were they founded, Shiseido or Sesderma?

Shiseido has been around longer, having been founded in Japan in 1872, whereas Sesderma was founded in Spain in 1989.

How many products are listed for Shiseido compared to Sesderma on this page?

Shiseido has twenty products listed on this page, while Sesderma has only one product.

Do both Shiseido and Sesderma offer products containing fragrance?

Yes, both Shiseido and Sesderma offer products containing fragrance, as the Azelac RU Serum from Sesderma and the majority of products on the Shiseido page include fragrance.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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