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Shiseido vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Shiseido and Sesderma are distinguished skincare brands originating from Japan and Spain, respectively. The Japanese house is beloved for its thoughtful array of moisturizers, cleansers, sunscreens, and serums formulated with key ingredients like glycerin, while the Spanish enterprise is known for advanced serums and meticulously engineered formulas featuring botanical extracts and active compounds. Both options suit sensitive skin best, with the former also favoring mature skin and the latter accommodating hyperpigmented and aging skin types. They differ primarily in their heritage and specific active approaches, with standout choices ranging from the Treatment Softener and Benefiance Wrinkle Smoothing Day Cream to the Azelac RU Serum.

Shiseido is a Japanese skincare brand founded in 1872 and owned by Shiseido Company, Limited.

corp.shiseido.comen.wikipedia.orgmarketscreener.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Shiseido and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Shiseido vs Sesderma products

Questions and answers

Shiseido or Sesderma: which is better?

Shiseido is a better choice for most shoppers because the products on this page offer a much wider variety of cleansers, moisturizers, and sunscreens tailored to different skin types. Sesderma is represented by only a single serum, Azelac RU Serum, which limits your routine options.

What is the difference between Shiseido and Sesderma?

Shiseido is a Japanese brand founded in 1872 with a large selection of cleansers, moisturizers, and serums on this page, while Sesderma is a Spanish brand founded in 1989 that features only the Azelac RU Serum here. Topical hyaluronic acid, found in Shiseido products, helps improve skin quality and signs of skin aging.

Dermatologic Therapy, 2022

Which is more affordable, Shiseido or Sesderma?

Reviewers note that Shiseido has a high price point, while information for Sesderma on this page does not mention pricing.

Which causes fewer breakouts, Shiseido or Sesderma?

Shiseido includes products with an average to high Lovi fit for acne-prone skin, whereas Sesderma offers the Azelac RU Serum, which has a high fit for acne-prone skin. Both brands feature formulations that may help with blemishes, though individual results vary.

When was Shiseido founded compared to Sesderma?

Shiseido was founded in 1872 in Japan, whereas Sesderma was founded later in 1989 in Spain.

How many products from Shiseido and Sesderma contain fragrance?

Among the products on this page, 15 out of 20 Shiseido products contain fragrance, while all 1 of the Sesderma products include fragrance.

What are some key ingredients shared across Shiseido's products?

Shiseido includes glycerin and hyaluronic acid across the products on this page. Topical hyaluronic acid helps improve skin quality and signs of skin aging.

Dermatologic Therapy, 2022

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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