Sesderma skincare
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
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Sesderma is beloved for its advanced serums and meticulously engineered formulas. Its products suit sensitive, hyperpigmented, and aging skin types best. The standout products for particular concerns include the Azelac RU Serum for acne-prone skin. Its botanical extracts and active compounds work synergistically to refine skin texture and promote a radiant complexion.
This page covers some of the most popular Sesderma products; for the whole Sesderma range, with a fit score for every product, use the Lovi app.
Sesderma serums and treatments
Questions and answers
Is Sesderma worth it?
Sesderma offers effective options for various skin concerns, with Lovi rating Sesderma-focused routines as Superior for dry, oily, sensitive, combination, and acne-prone skin. The brand was founded in Spain in 1989 and features targeted treatments like Azelac RU Serum.
What are Sesderma's best products?
Lovi rates Azelac RU Serum High for acne-prone skin and skin with dark spots. The Sesderma brand-focused routine achieves a Superior fit for dry, oily, sensitive, combination, and acne-prone skin.
Does Sesderma cause breakouts?
Sesderma offers products like Azelac RU Serum that help manage blemishes, and Lovi rates this serum High for acne-prone skin. It contains ingredients like azelaic acid that help clear acne vulgaris according to clinical studies.
Is Sesderma fragrance-free?
No, the Sesderma products on this page are not fragrance-free, as Azelac RU Serum contains fragrance.
What are the key ingredients in Sesderma products?
Azelac RU Serum contains azelaic acid and other active ingredients that help target dark spots and blemishes. Lovi rates the Azelac RU Serum High for skin with dark spots and acne-prone skin.
How do I build a Sesderma skincare routine?
To build a Sesderma skincare routine, you can use the Azelac RU Serum, which Lovi rates High for combination skin and acne-prone skin. The Sesderma-focused routine rates Superior for dry skin, oily skin, sensitive skin, combination skin, and acne-prone skin.
Where can I buy Sesderma, and how much does it cost?
Sesderma products can be bought at stores in Germany. Prices on the page range from 35.16 euros to 35.16 euros, with most falling within that range.
What are good alternatives to Sesderma?
Good alternatives to Sesderma include brands like ISDIN, Heliocare, Theramid, Mesoestetic, and Endocare. Lovi lists dedicated pages for these similar skincare brands.
Sesderma vs ISDIN: which is better?
Sesderma and ISDIN offer comparable performance, as Lovi rates both as Superior for dry, oily, sensitive, combination, and acne-prone skin.
Who owns Sesderma, and where is it from?
Sesderma is a Spanish brand founded in 1989, owned by Grupo Sesderma since 2026.
Is Sesderma cruelty-free?
PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list Sesderma as cruelty-free.
Research behind Sesderma's key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Behind these ratings
Lovi rates every product from its full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.

