A+ 345 Relief Cream for oily acne-prone skin
Niacinamide
Hyaluronic Acid
Coptis Japonica Root ExtractAverage
- AverageOily Skin Fit
- AverageEffectiveness
- ExcellentSafety
Works for oily acne-prone skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate suitability for your oily skin as niacinamide helps regulate sebum and provide hydration, though it lacks more potent ingredients for optimal oil control.
- The inclusion of glycerin and hyaluronic acid ensures excellent moisturizing treatment, plumping and hydrating your skin effectively.
- The formulation is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components like Centella Asiatica Leaf Extract.
How to apply
- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
People Say
★4.4Overall rating based on 2.5k+ reviewsBased on a very large amount of data, this lightweight, gel-like cream is widely celebrated by users with oily, combination, and sensitive skin for its ability to soothe redness and fade post-acne marks without clogging pores. However, those with dry skin often find it insufficiently moisturizing, and a subset of users report breakouts or fungal acne triggers despite its soothing claims.
Highlights
Lightweight & fast-absorbing Mostly Mentioned
- “absorbs in seconds”
- “non-greasy finish”
- “gel-cream texture”
- “no sticky residue”
- “feels like water”
Ideal for oily/combo skin Often Mentioned
- “perfect for summer”
- “doesn't clog pores”
- “balances sebum”
- “light enough for day”
- “great under makeup”
Soothing & calming Often Mentioned
- “calms redness instantly”
- “cools irritated skin”
- “soothes inflammation”
- “reduced heat”
- “helped sensitive barrier”
Fades acne marks Sometimes Noted
- “lightened dark spots”
- “helped with PIE”
- “faded acne scars”
- “cleared blemishes”
- “evened skin tone”
Not moisturizing enough Sometimes Noted
- “too light for dry skin”
- “skin felt tight”
- “need to layer”
- “not occlusive enough”
- “dried me out”
Caused breakouts Rarely Noted
- “gave me whiteheads”
- “caused closed comedones”
- “broke me out”
- “bad purging”
- “clogged my pores”
Fungal acne trigger Rarely Noted
- “triggered fungal acne”
- “tiny itchy bumps”
- “not FA safe”
- “ruined skin texture”
- “flare-up”
Texture/pilling issues Rarely Noted
- “pills under sunscreen”
- “tacky finish”
- “films on face”
- “separates makeup”
- “rubbed off”
Sources: lovi.care, iherb.com, yesstyle.com, reddit.com, cosmetify.com, skinsort.com, and more
Questions and answers
How well does A+ 345 Relief Cream work for oily acne-prone skin?
A+ 345 Relief Cream works moderately well for oily acne-prone skin, as niacinamide helps control oil while hyaluronic acid and glycerin provide hydration without irritation. However, this skin type needs a moisturizing treatment that features stronger oil-controlling ingredients, lightweight textures without heavy oils, and components that support the skin barrier while managing breakouts.
Which ingredients make this cream a good fit for oily acne-prone skin?
Niacinamide, hyaluronic acid, and glycerin make this cream a good fit because they help control oil and keep your skin hydrated without feeling heavy. Oily acne-prone skin needs lightweight hydration, ingredients that balance oil, and soothing plant extracts like centella asiatica to keep pores clear and calm.
What does Niacinamide do for oily acne-prone skin?
Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Journal of Cosmetic and Laser Therapy, 2006Journal of Cosmetic Dermatology, 2024
What does Hyaluronic Acid do for oily acne-prone skin?
Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
The Journal of Investigative Dermatology, 2017Journal of Cosmetic Dermatology, 2022
Where does it go in a skincare routine for oily acne-prone skin?
This moisturizing treatment goes in the morning right before sunscreen and in the evening as the last step after your treatment. It helps hydrate your oily skin without irritation, though oily acne-prone skin also needs more potent ingredients for optimal oil control.
International Journal of Cosmetic Science, 2020Clinical, Cosmetic and Investigational Dermatology, 2017
Can I use this cream with retinol, and in what order?
You can use this cream alongside retinol by applying the cream after your retinol to help keep your skin calm and hydrated. Using a moisturizing treatment with ingredients like hyaluronic acid and soothing plant extracts is unlikely to cause irritation and may help your skin tolerate retinol better.
Cutis, 2006Clinical, Cosmetic and Investigational Dermatology, 2017
How often should I use it?
You can use this moisturizing treatment twice a day as part of your morning and evening routine to keep your skin hydrated. Regular daily application helps improve moisture levels and skin comfort while supporting your skin barrier.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can it clog pores, cause breakouts or purging for oily acne-prone skin?
This cream is unlikely to clog pores or cause breakouts on oily acne-prone skin, as it has a safe formula free of harsh ingredients and includes soothing components like Centella Asiatica Leaf Extract. However, because it only offers moderate suitability for your skin, an ideal product for this skin type needs more potent ingredients for optimal oil control.
Can I use this cream around the eyes or on my body?
You can use this moisturizing treatment around your eyes and on your body, as its gentle ingredients are safe for delicate areas. It helps hydrate and soothe the skin without causing irritation, though oily acne-prone skin needs stronger oil-controlling ingredients for an ideal fit.
Is it fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.
Dermatologic Therapy, 2022Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.
Molecules, 2023Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical steroid withdrawal is driven by excess mitochondrial NAD+ metabolism that can be successfully targeted using complex I-inhibiting interventions such as metformin and berberine.
The Journal of Investigative Dermatology, 2025Topical steroid withdrawal presents as a distinct dermatopathology characterized by burning, flushing, thermodysregulation, and elevated mitochondrial NAD+ oxidation, which can be improved by targeting complex I with metformin or berberine.
MedRxiv, 2024Hydroxypropyl methylcellulose hydrogel formulations of berberine chloride-loaded escinosomes increased skin residence time and transdermal permeability while maintaining high safety and biocompatibility without skin irritation.
International Journal of Biological Macromolecules, 2020
Ingredients
Water, Propanediol, Glycerin, Cyclohexasiloxane, 1,2-Hexanediol, Niacinamide, Caprylic Capric Triglyceride, Polyglycerin-3, Panthenol, Polyglyceryl-10 Stearate, Hydrogenated Polydecene, Hydrogenated Poly C6-14 Olefin, Dicaprylyl Carbonate, Ammonium Acryloyldimethyltaurate Vp Copolymer, C14-22 Alcohols, Polymethylsilsesquioxane, C12-20 Alkyl Glucoside, Butylene Glycol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Ethylhexylglycerin, Polyquaternium-51, Tromethamine, Hyaluronic Acid, Coptis Japonica Root Extract, Houttuynia Cordata Extract, Oenothera Biennis Flower Extract, Beta-Glucan, Resveratrol, Gardenia Florida Fruit Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Opuntia Ficus-Indica Stem Extract, Hydrolyzed Hyaluronic Acid, Centella Asiatica Leaf Extract, Phenoxyethanol, Hibiscus Sabdariffa Flower Extract, Tocopherol, Corallina Officinalis Extract, Ceramide Np
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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