Medicube vs ISDIN
Medicube and ISDIN are a 2016 South Korean brand owned by APR Corp. and a 1975 Spanish brand owned by Puig, respectively. Skincare enthusiasts adore Medicube for its moisturizers, serums, toners, and masks featuring niacinamide, collagen, and hyaluronic acid, while ISDIN is beloved for its moisturizers, advanced sunscreens, serums, and eye products. The first brand suits dry and oily acne-prone skin best with targeted options like the AGE-R Booster Gel, Deep Peptide Radiance Mask, and Deep Lifting Peptide Eye Cream, whereas the second brand suits dry and combination skin best with standouts like Fusion Water, Eryfotona Actinica, and K-Ox Eyes. Ultimately, they differ in their heritage and precise active profiles, with both delivering profound results through meticulously crafted formulas.
Medicube is a Korean skincare brand founded in 2016 and owned by APR Corp..
medicubereviews.co.ukglossy.co
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
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This page compares some of the most popular Medicube and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Medicube vs ISDIN products
People Say
Hydration and Moisture Mostly MentionedMostly Mentioned
- “skin feels bouncier and hydrated — Medicube PDRN Pink Peptide Serum”
- “glass skin — Medicube PDRN Pink Collagen Gel Mask”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Lightweight and Non-Greasy Texture Not notedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
Skin Texture and Smoothing Often MentionedOften Mentioned
- “gives my skin a smooth, glass-like finish — Medicube Zero Pore Pad”
- “skin feels smoother — Medicube PDRN Pink Peptide Serum”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
- “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum”
Glow and Brightening Often MentionedSometimes Noted
- “gave me instant glass skin — Medicube Collagen Jelly Cream”
- “woke up with glowing skin — Medicube Collagen Night Wrapping Mask”
- “Dark spots go away faster — Medicube Deep Vita C Pad”
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
Acne and Pore Care Often MentionedNot noted
- “Pores drastically reduced — Medicube Zero Foam Cleanser”
- “Removes every trace of oil — Medicube Red Foam Cleanser”
- “noticed a real difference in pore visibility — Medicube Zero Pore Pad”
High Price Point Sometimes NotedOften Mentioned
- “tube is tiny for the price — Medicube Collagen Night Wrapping Mask”
- “price is steep — Medicube PDRN Pink Collagen Gel Mask”
- “price is a bit steep — Medicube Red Succinic Acid Peeling Pad”
- “very expensive — ISDIN Eryfotona Actinica”
Strong Fragrance and Scent Often MentionedOften Mentioned
- “slightly fishy smell — Medicube PDRN Pink Peptide Serum”
- “smells like old lady perfume — Medicube Collagen Jelly Cream”
- “smell is overpowering — ISDIN Eryfotona Actinica”
- “lingering headache inducing effect — ISDIN K-Ox Eyes”
Packaging and Application Issues Sometimes NotedSometimes Noted
- “Pump stopped working — ISDIN Hyaluronic Concentrate”
- “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
- “Pilled up on my skin — ISDIN Hyaluronic Moisture”
- “messy — Medicube PDRN Pink Collagen Gel Mask”
Medicube vs ISDIN routines for dry skin
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Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
€19.75
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Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
€12.59
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Moisturizer
d'Alba First Spray Serum
Morning · Evening · Once a week
€16.99
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SPF
Fusion Water
Morning
€25.99
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€10.97
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Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
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Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
€19.00
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Cleanser
Zero Foam Cleanser
Morning · Evening · Once a week
€12.79
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Hydrating Toner
Triple Collagen Toner
Morning
€11.64
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Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
€16.99
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SPF
Australian Gold Botanical Lotion SPF 30
Morning
€21.04
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€10.97
-
Serum or Treatment
One Day Exosome Shot 2000
Evening · Once a week
€16.00
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Nourishing Mask
Deep Peptide Radiance Mask
Once a week
€7.99
Medicube vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
€11.75
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€16.59
-
Moisturizer
CeraVe PM Facial Moisturizing Lotion
Morning · Evening · Once a week
€38.99
-
SPF
Eryfotona Actinica
Morning
€32.49
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Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€104.00
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Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
€16.90
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Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
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Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
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Cleansing Mask
Dr. Sebagh Deep Exfoliating Mask
Once a week
€81.80
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Cleanser
Red Foam Cleanser
Morning · Evening · Once a week
€15.60
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Hydrating Toner
Triple Collagen Toner
Morning · Once a week
€11.64
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
€16.99
-
SPF
make p:rem UV Defense Me Blue Ray Sun Cream
Morning
€32.80
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€104.00
-
Cleansing Toner
Zero Pore Pad
Evening
€16.98
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Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Zero Pore Blackhead Mud Mask
Once a week
€15.89
Medicube vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
€39.99
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Some By Mi Yuja Niacin Brightening Moisture Gel Cream
Morning · Evening · Once a week
€13.67
-
SPF
Eryfotona Actinica
Morning
€32.49
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€104.00
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€16.98
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Origins Original Skin Retexturizing Mask with Rose Clay
Once a week
€28.50
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Cleanser
Red Foam Cleanser
Morning · Evening · Once a week
€15.60
-
Hydrating Toner
Triple Collagen Toner
Morning · Once a week
€11.64
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
€16.99
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€104.00
-
Cleansing Toner
Zero Pore Pad
Evening
€16.98
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Zero Pore Blackhead Mud Mask
Once a week
€15.89
Questions and answers
Medicube or ISDIN: which is better?
Both brands are great choices depending on your goals, with Medicube standing out for glow and pore care and ISDIN praised for ultralight textures. Lovi gives ISDIN a Superior routine fit for oily, combination, sensitive, acne-prone, and mature skin, while Medicube fits these skin types at a High level.
What is the difference between Medicube and ISDIN?
Medicube is best for glow and brightening as well as acne and pore care, while ISDIN offers a more lightweight and non-greasy texture with ultralight sunscreens. Lovi rates ISDIN with superior routine fit levels across most skin types, whereas Medicube fits best specifically for dry skin, oily skin, and oily acne-prone skin.
Medicube or ISDIN for dry skin?
Both Medicube and ISDIN offer a Superior Lovi routine fit for dry skin, though Medicube has more fragrance-free options on this page. Topical hyaluronic acid helps improve skin quality and hydration signs.
Medicube or ISDIN: which moisturizer is better?
Both Medicube and ISDIN offer lightweight moisturizers, but Medicube may be better for deep hydration and a glowing finish while ISDIN tends to be lighter. For dry skin, both brands achieve a Superior fit level on Lovi. Niacinamide in these formulas helps improve skin aging and pigmentation.
Which is more affordable, Medicube or ISDIN?
Medicube is more affordable, as ISDIN has a high price point. At the same time, Medicube faces pricing issues with smaller product quantities.
Between Medicube and ISDIN, which brand offers better results for glow and brightening?
Medicube does better for glow and brightening compared to ISDIN. Ingredients like niacinamide help reduce cutaneous pigmentation and suppress melanosome transfer.
How do the founding years and corporate owners of Medicube and ISDIN compare?
Medicube was founded in 2016 in South Korea and is owned by APR Corp., whereas ISDIN was founded earlier in 1975 in Spain and is owned by Puig.
Which brand has more products listed without fragrance: Medicube or ISDIN?
Medicube has more products listed without fragrance, with 23 out of 25 products on this page lacking fragrance compared to 3 out of 8 for ISDIN.
Medicube or ISDIN for oily skin?
ISDIN is the better fit for oily skin, earning a Superior routine fit rating compared to Medicube's High level. ISDIN features ultralight sunscreens that reviewers mostly mention for being lightweight and non-greasy.
Medicube or ISDIN for sensitive skin?
Both Medicube and ISDIN are suitable, with Lovi giving Medicube a High fit and ISDIN a Superior fit for sensitive skin. Reviewers note that the products on this page for Medicube help with deep hydration, while ISDIN offers ultralight sunscreens.
Medicube or ISDIN for acne-prone skin?
Both brands are great choices for acne-prone skin, with Lovi rating Medicube as High and ISDIN as Superior for this skin type. Medicube features key ingredients like salicylic acid and niacinamide that help manage blemishes, while the products on this page from ISDIN are known for offering ultralight sunscreens and lightweight moisturizers.
Research behind their key ingredients
Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Effect of Camellia japonica oil on human type I procollagen production and skin barrier function
Protective effects of Camellia japonica flower extract against urban air pollutants
Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Functional properties and skin care effects of sodium trehalose sulfate
Composition characterization and clinical efficacy study of a salmon egg extract
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from Paeonia lactiflora
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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