Medicube vs ISDIN
Medicube and ISDIN are well-regarded international skincare companies that offer carefully formulated products for various skin types. The Korean brand founded in 2016 features moisturizers, serums, toners, and masks with niacinamide, collagen, and hyaluronic acid to suit dry and oily acne-prone skin, while the Spanish brand established in 1975 provides elegant moisturizers, advanced sunscreens, restorative serums, and eye products that suit dry and sensitive skin best. While both lines use thoughtfully balanced formulas to address concerns like dark spots, acne, and aging, the former focuses on profound results through active ingredients, and the latter delivers gentle daily comfort and dependable protection.
Medicube is a Korean skincare brand founded in 2016 and owned by APR Corp..
medicubereviews.co.ukglossy.co
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
puig.combeautymatter.comuploads.puig.com
This page compares some of the most popular Medicube and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Medicube vs ISDIN products
People Say
Hydration and Moisture Mostly MentionedMostly Mentioned
- “skin feels bouncier and hydrated — Medicube PDRN Pink Peptide Serum”
- “glass skin — Medicube PDRN Pink Collagen Gel Mask”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Lightweight and Non-Greasy Texture Not notedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
Skin Texture and Smoothing Often MentionedOften Mentioned
- “gives my skin a smooth, glass-like finish — Medicube Zero Pore Pad”
- “skin feels smoother — Medicube PDRN Pink Peptide Serum”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
- “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum”
Glow and Brightening Often MentionedSometimes Noted
- “gave me instant glass skin — Medicube Collagen Jelly Cream”
- “woke up with glowing skin — Medicube Collagen Night Wrapping Mask”
- “Dark spots go away faster — Medicube Deep Vita C Pad”
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
Acne and Pore Care Often MentionedNot noted
- “Pores drastically reduced — Medicube Zero Foam Cleanser”
- “Removes every trace of oil — Medicube Red Foam Cleanser”
- “noticed a real difference in pore visibility — Medicube Zero Pore Pad”
High Price Point Sometimes NotedOften Mentioned
- “tube is tiny for the price — Medicube Collagen Night Wrapping Mask”
- “price is steep — Medicube PDRN Pink Collagen Gel Mask”
- “price is a bit steep — Medicube Red Succinic Acid Peeling Pad”
- “very expensive — ISDIN Eryfotona Actinica”
Strong Fragrance and Scent Often MentionedOften Mentioned
- “slightly fishy smell — Medicube PDRN Pink Peptide Serum”
- “smells like old lady perfume — Medicube Collagen Jelly Cream”
- “smell is overpowering — ISDIN Eryfotona Actinica”
- “lingering headache inducing effect — ISDIN K-Ox Eyes”
Packaging and Application Issues Sometimes NotedSometimes Noted
- “Pump stopped working — ISDIN Hyaluronic Concentrate”
- “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
- “Pilled up on my skin — ISDIN Hyaluronic Moisture”
- “messy — Medicube PDRN Pink Collagen Gel Mask”
Medicube vs ISDIN routines for dry skin
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Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
$19.99
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Hydrating Toner
Pyunkang Yul Calming Deep Moisture Toner
Morning
$16.99
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Moisturizer
SKIN1004 Madagascar Centella Probio-Cica Enrich Cream
Morning · Evening · Once a week
$22.00
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SPF
Fusion Water
Morning
$38.00
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
$21.70
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Serum or Treatment
Flavo-C Serum
Evening · Once a week
$115.00
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Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
$22.00
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Cleanser
Zero Foam Cleanser
Morning · Evening · Once a week
$29.33
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Hydrating Toner
Triple Collagen Toner
Morning
$18.30
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Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
$29.97
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SPF
d'Alba Piedmont Waterfull Mild Sunscreen
Morning
$15.99
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
$21.70
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Serum or Treatment
One Day Exosome Shot 2000
Evening · Once a week
$19.99
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Nourishing Mask
Collagen Night Wrapping Mask
Once a week
$19.00
Buy ISDIN routine · $255.68 · 94% fit
Buy Medicube routine · $154.28 · 91% fitSee multi-brand routine · 99% fit
Medicube vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
$15.97
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
$15.60
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
$18.99
-
SPF
Eryfotona Actinica
Morning
$46.00
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
$50.00
-
Cleansing Toner
Pixi Glow Tonic
Evening
$28.42
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
$115.00
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
$69.00
-
Cleansing Mask
Revision Skincare Black Mask
Once a week
$79.00
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Cleanser
Red Foam Cleanser
Morning · Evening · Once a week
$14.90
-
Hydrating Toner
Triple Collagen Toner
Morning · Once a week
$18.30
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
$29.97
-
SPF
CeraVe AM Facial Moisturizing Lotion SPF 30
Morning
$14.97
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
$50.00
-
Cleansing Toner
Zero Pore Pad
Evening
$18.90
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
$69.00
-
Cleansing Mask
Zero Pore Blackhead Mud Mask
Once a week
$18.90
Buy ISDIN routine · $437.98 · 93% fit
Buy Medicube routine · $234.94 · 88% fitSee multi-brand routine · 98% fit
Medicube vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
$28.08
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
$25.60
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
$18.99
-
SPF
Eryfotona Actinica
Morning
$46.00
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
$50.00
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
$18.90
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
$115.00
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
$69.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
$58.00
-
Cleanser
Red Foam Cleanser
Morning · Evening · Once a week
$14.90
-
Hydrating Toner
Triple Collagen Toner
Morning · Once a week
$18.30
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
$29.97
-
SPF
CeraVe AM Facial Moisturizing Lotion SPF 30
Morning
$14.97
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
$50.00
-
Cleansing Toner
Zero Pore Pad
Evening
$18.90
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
$69.00
-
Cleansing Mask
Zero Pore Blackhead Mud Mask
Once a week
$18.90
Buy ISDIN routine · $429.57 · 93% fit
Buy Medicube routine · $234.94 · 88% fitSee multi-brand routine · 97% fit
Questions and answers
Medicube or ISDIN: which is better?
Medicube is better for glow, brightening, acne, and pore care, whereas ISDIN is better for lightweight, non-greasy textures and sunscreens.
What is the difference between Medicube and ISDIN?
Medicube offers superior glow, brightening, acne, and pore care with most products on this page listing no fragrance, whereas ISDIN is better for lightweight textures and sunscreen options. For routine fit, Lovi rates Medicube as High and ISDIN as Superior across most skin types, while both are rated Superior for dry skin.
Medicube or ISDIN for dry skin?
Both Medicube and ISDIN fit dry skin well, with Lovi giving them an equal routine fit level of Superior. Medicube features deep hydration moisturizers, while ISDIN offers lightweight moisturizers.
Dermatologic Therapy, 2022Dermatology Practical & Conceptual, 2022
Medicube or ISDIN: which moisturizer is better?
Medicube offers superior moisturizers for mature skin and dry sensitive skin like its Collagen Jelly Cream, while ISDIN features lightweight options such as its Hyaluronic Concentrate. For hydration and moisture, both brands perform equally well according to reviewer themes.
Which is more affordable, Medicube or ISDIN?
Medicube is more affordable, as ISDIN is noted for having a high price point. Review themes on the products on this page show that a high price point is a negative point specifically for Medicube, but shoppers frequently mention high prices for ISDIN overall.
Medicube or ISDIN for fragrance-free options?
Medicube offers significantly more fragrance-free options, with 23 out of 25 products on this page listing no fragrance. In contrast, only 3 of the 8 ISDIN products on this page are fragrance-free.
Medicube or ISDIN for oily skin?
ISDIN offers a Superior Lovi fit level for oily skin, whereas Medicube reaches a High level on this page. Reviewers note that ISDIN excels in lightweight and non-greasy textures.
Medicube or ISDIN for sensitive skin?
For sensitive skin, both brands work well, but ISDIN has a Superior routine fit while Medicube has a High fit. Reviewers often mention that Medicube is soothing and gentle, whereas ISDIN is known for its skin-friendly sunscreens.
Medicube or ISDIN for acne-prone skin?
For acne-prone skin, both brands work well as Lovi rates Medicube High and ISDIN Superior. Medicube features acne and pore care among the products on this page.
Medicube or ISDIN for mature skin?
Both Medicube and ISDIN fit mature skin at a High level on this page. Medicube stands out for glow and brightening, while ISDIN is praised for its ultralight sunscreens and lightweight moisturizers. Topical retinol and hyaluronic acid help support mature skin and reduce signs of aging.
The Journal of Investigative Dermatology, 2000Dermatologic Therapy, 2022
Medicube or ISDIN for skin with dark spots?
Both Medicube and ISDIN are a High fit for skin with dark spots. Niacinamide helps reduce pigmentation by suppressing melanosome transfer.
Research behind their key ingredients
Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Effect of Camellia japonica oil on human type I procollagen production and skin barrier function
Protective effects of Camellia japonica flower extract against urban air pollutants
Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Functional properties and skin care effects of sodium trehalose sulfate
Composition characterization and clinical efficacy study of a salmon egg extract
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from Paeonia lactiflora
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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