Shiseido Bio-Performance Skin Filler for acne-prone skin

Sodium Hyaluronate
Glycerin
Bupleurum Falcatum Root Extract
Lavandula Angustifolia Oil Lavender Oil
Trifolium Pratense Flower Extract
Average
- AverageCombination Skin Fit
- AverageEffectiveness
- HighSafety
Works for acne-prone skin; other moisturizers fit it better.
- Clinical, Cosmetic and Investigational Dermatology, 2017
- Journal of Pharmacy & Pharmaceutical Sciences, 2015
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate suitability for combination skin due to the presence of glycerin and butylene glycol, which provide excellent hydration and plumpness, but lacks targeted ingredients to effectively address your acne, blemishes, and breakouts.
- While the formula is safe for your combination skin and free of harsh ingredients, it does not offer sufficient oil control for your oilier areas.
- The product is safe for your skin, with no risks of irritation.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
People Say
★4.6Overall rating based on 1.0k+ reviewsBased on a very large amount of data, users report a significant plumping and volumizing effect that enhances skin bounce and hydration, with results often likened to mild aesthetic procedures. The innovative two-step day/night system is frequently praised for its texture and effectiveness on fine lines. The primary drawbacks mentioned are the high cost and the commitment to a multi-step routine.
Highlights
Visible plumping Mostly Mentioned
- “Skin looked and felt juicier”
- “crazy-plump skin”
- “instant filler benefits”
Deep hydration Often Mentioned
- “Moisture, moisture, moisture”
- “eliminated dryness”
- “intense hydration”
Nice texture Often Mentioned
- “Silkiest texture”
- “absorbs quickly”
- “non-sticky finish”
Expensive product Often Mentioned
- “Doesn't worth the price”
- “very expensive”
- “investment skincare”
Softens lines Sometimes Noted
- “Softened lines”
- “wrinkles less visible”
- “smoother under-eye area”
Cumbersome routine Rarely Noted
- “Two-step process is a hassle”
- “need to remember both”
- “time-consuming routine”
Subtle results Rarely Noted
- “Didn't notice any changes”
- “didn't work for me”
- “results are subtle”
Sources: lovi.care, macys.com, lookfantastic.com, perfumesclub.co.uk, influenster.com, johnlewis.com, and more
Questions and answers
How well does Shiseido Bio-Performance Skin Filler work for acne-prone skin?
Shiseido Bio-Performance Skin Filler works moderately well for acne-prone skin, providing good hydration and plumpness while remaining safe and unlikely to cause irritation. However, it lacks targeted ingredients to address breakouts and does not offer enough oil control for oilier areas. Acne-prone skin needs products with ingredients like niacinamide and hyaluronic acid that balance hydration and help control excess oil without causing irritation.
Which ingredients make this serum a good fit for acne-prone skin?
This serum works for your skin because it contains sodium hyaluronate and glycerin for hydration, though it lacks targeted ingredients for breakouts. To fit acne-prone skin best, a product of this type needs ingredients like niacinamide and hyaluronic acid to manage blemishes and control oil while keeping skin balanced.
What does Hyaluronic Acid do for acne-prone skin?
Hyaluronic acid helps acne-prone skin by soothing irritation, calming redness, and keeping the skin balanced without clogging pores. When combined with targeted ingredients like zinc oxide, it may also help reduce breakouts.
What does Glycerin do for acne-prone skin?
Glycerin helps keep acne-prone skin hydrated and calm without clogging pores or feeling heavy. It supports the skin barrier so it stays soft and smooth while handling everyday treatments.
The British Journal of Dermatology, 2008International Journal of Toxicology, 2019
Where does it go in a skincare routine for acne-prone skin?
This treatment goes in the evening routine after cleansing and toning, and before your moisturizer. While it is safe and provides good hydration for your skin, acne-prone skin works best with products that also offer oil control and targeted ingredients for blemishes.
Can I use it with retinol, and in what order?
Yes, you can use this moisturizing treatment with retinol by applying it after your retinol product to help keep your skin hydrated and reduce dryness. An acne-prone skin routine needs ingredients that control oil and target breakouts, along with soothing elements.
How often should I use it?
You can use this treatment in your evening routine, applying it after your cleansing toner and before your moisturizer. It is safe for your skin with no risks of irritation, though acne-prone skin needs products that provide targeted blemish care and oil control alongside hydration.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can it clog pores, cause breakouts or purging for acne-prone skin?
This moisturizing treatment is unlikely to cause irritation on acne-prone skin, but it lacks the oil control and targeted ingredients needed to address breakouts. Acne-prone skin requires lightweight formulas with oil-balancing and blemish-clearing ingredients to keep pores clear.
Can I use it around the eyes or on my body?
This moisturizing treatment is safe to use around the eyes and on the body, as it has a gentle formula with very good skin tolerance. However, because the skin around the eyes and on various body areas can be much thinner than facial skin, you should patch test first to ensure it feels comfortable.
Is it fragrance-free and alcohol-free?
It has no fragrance and contains drying alcohol (alcohol).
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine.
Journal of Pharmacy & Pharmaceutical Sciences, 2015Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Polysaccharide-based O/W emulsions incorporated with lavender essential oil applied to cellulosic support are non-irritating, provide softness and moisturizing effects, and are safe for topical patch applications.
International Journal of Biological Macromolecules, 2021Gellan gum hydrogel films co-encapsulating ofloxacin with tea tree or lavender oil achieved 98% wound contraction and completely healed epidermis in rats after ten days of treatment compared to baseline.
International Journal of Biological Macromolecules, 2021Topical application of lavender oil significantly promoted wound contraction, collagen synthesis, and fibroblast differentiation with up-regulation of TGF-beta in a rat model compared to control.
BMC Complementary and Alternative Medicine, 2016Daily topical application of a combination of Trifolium pratense flower extract and a biomimetic peptide increased anagen hair by 13%, decreased telogen hair density by 29%, and increased the anagen/telogen ratio by 46% over baseline in 30 volunteers with receding hair compared to placebo over 4 months.
Journal of Cosmetic Science, 2013A water-in-oil microemulsion vehicle significantly enhanced the intradermal delivery of genistein, daidzein, and biochanin A in excised guinea pig and Yucatan micropig skin, with genistein exhibiting the most marked increase in skin accumulation and effectively preventing UV irradiation-induced erythema formation.
Chemical & Pharmaceutical Bulletin, 2010Topical administration of Trifolium pratense extract ointment significantly increased collagen production, epidermis thickness, fibroblast distribution, wound contraction, and Bcl-2 mRNA levels while reducing Bax and p53 mRNA levels in Wistar rats compared to non-intervention controls.
Biotechnic & Histochemistry, 2021
Why other moisturizers fit acne-prone skin better
A peel-off facial mask containing myoinositol and trehalose-loaded liposomes improved adult female acne by decreasing lesion counts, sebum production, GAGS scores, and local androgen levels while increasing beclin-1 levels.
Journal of Cosmetic Dermatology, 2017A Tris/Arg-formulated cleanser significantly decreased noninflammatory and inflammatory acne and pore size with keratotic plugs compared to an AEC/AC cleanser in male Thai subjects with mild to moderate acne over 4 weeks.
Journal of Cosmetic Dermatology, 2020
Ingredients
Water, Dimethicone, Butylene Glycol, Dipropylene Glycol, Alcohol, Glycerin, Behenyl Alcohol, Triethylhexanoin, Silica, Phytosteryl Octyldodecyl Lauroyl Glutamate, Alpha-Glucan Oligosaccharide, Aminopropyl Dimethicone, Trifolium Pratense Flower Extract, Lavandula Angustifolia Oil Lavender Oil, Bupleurum Falcatum Root Extract, Batyl Alcohol, Hydrogenated Palm Oil, Behenic Acid, Elaies Guineensis Kernel Oil Palm Kernel Oil, Peg-60 Glyceryl Isostearate, Peg-10 Dimethicone, Elaies Guineensis Oil Palm Oil, Tocopherol, Sodium Metaphosphate, Potassium Hydroxide, Sodium Metabisulfite, Cinnamomum Cassia Bark Extract, Citric Acid, Phenoxyethanol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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