Neutrogena vs ISDIN
Neutrogena and ISDIN are well-regarded skincare brands that offer thoughtfully formulated moisturizers, sunscreens, and cleansers designed for daily care. The American brand, founded in 1930 and owned by Kimberly-Clark Corporation since 2026, relies on key ingredients like glycerin, hyaluronic acid, and dimethicone to suit mature skin and skin with dark spots best. Conversely, the Spanish brand, founded in 1975 and owned by Puig, crafts advanced formulas featuring reliable results that suit sensitive skin and acne-prone skin best. While both lines provide standout solutions for specific concerns, they differ in their targeted active components and ideal skin types.
Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.
investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
puig.combeautymatter.comuploads.puig.com
This page compares some of the most popular Neutrogena and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Neutrogena vs ISDIN products
People Say
Lightweight and non-greasy texture Mostly MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “Absorbs instantly without sticky residue — Neutrogena Hydro Boost Water Gel”
Deep hydration and moisture Mostly MentionedMostly Mentioned
- “Skin looked plumper and radiant — Neutrogena HYDRO BOOST WATER CREAM”
- “It also hydrates my skin. This cream has been so easy to add to my routine. — Neutrogena Retinol Regenerating Cream”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
Sensitive skin friendly and gentle Mostly MentionedOften Mentioned
- “leaves skin soft and balanced — Neutrogena Ultra Gentle Daily Cleanser”
- “love that it has no scent — Neutrogena Ultra Gentle Daily Cleanser”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Makeup compatibility and base Sometimes NotedOften Mentioned
- “Foundation glides right over it — Neutrogena Hydro Boost Water Gel”
- “Concealer doesn't cake or get stuck in crevices — Neutrogena Hydro Boost Eye Gel-Cream”
- “acts like a primer — ISDIN Eryfotona Actinica”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Skin texture improvement and anti-aging Sometimes NotedRarely Noted
- “Skin is looking smoother — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “Deep lines have softened — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “I can see a difference in my forehead wrinkles. — Neutrogena Retinol Regenerating Cream”
- “skin was much smoother — ISDIN Retinal Intense Serum”
Cooling and soothing sensation Rarely NotedSometimes Noted
- “Feels amazing and cold on the skin — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
- “Feels refreshing and cool on application — Neutrogena Hydro Boost Water Gel”
- “applicator has a cooling effect — ISDIN K-Ox Eyes”
Price vs quantity and high cost Sometimes NotedOften Mentioned
- “Jar is too small for the price — Neutrogena Hydro Boost Water Gel”
- “Runs out quickly — Neutrogena HYDRO BOOST WATER CREAM”
- “Tube is tiny for the cost — Neutrogena Hydro Boost Eye Gel-Cream”
- “very expensive — ISDIN Eryfotona Actinica”
Strong fragrance and scent issues Sometimes NotedOften Mentioned
- “Smell is too overpowering and lingering — Neutrogena Hydro Boost Water Gel”
- “Scent is so off-putting — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “smell is overpowering — ISDIN Eryfotona Actinica”
- “lingering headache inducing effect — ISDIN K-Ox Eyes”
Packaging and design issues Sometimes NotedRarely Noted
- “Pump stopped working — ISDIN Hyaluronic Concentrate”
- “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
- “Eye holes are too small — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
Neutrogena vs ISDIN routines for dry skin
-
Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
SAR 297.00
-
Moisturizer
SKIN1004 Madagascar Centella Probio-Cica Enrich Cream
Morning · Evening · Once a week
SAR 48.00
-
SPF
Fusion Water
Morning
SAR 75.00
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
SAR 65.11
-
Cleansing Toner
ROUND LAB 1025 Dokdo Cleansing Water
Evening
SAR 72.64
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
SAR 848.48
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
SAR 130.30
-
Nourishing Mask
Mediheal Watermide Essential Mask
Once a week
SAR 234.73
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
SAR 17.19
-
Hydrating Toner
Alcohol-Free Toner
Morning
SAR 97.00
-
Moisturizer
Hydro Boost Hyaluronic Acid Serum
Morning · Evening · Once a week
SAR 150.91
-
SPF
Clear Face Liquid Lotion Sunscreen
Morning
SAR 115.51
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
SAR 99.99
-
Cleansing Toner
Blackhead Eliminating Cleansing Toner
Evening
SAR 72.68
-
Serum or Treatment
Stubborn Marks PM Treatment
Evening · Once a week
SAR 97.00
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
SAR 130.30
-
Nourishing Mask
Hydro Boost Hydrating Hydrogel Mask
Once a week
SAR 74.18
Buy ISDIN routine · SAR 1,771.26 · 92% fit
Buy Neutrogena routine · SAR 854.76 · 69% fitSee multi-brand routine · 96% fit
Neutrogena vs ISDIN routines for oily skin
-
Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
SAR 36.33
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
SAR 53.04
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
SAR 39.70
-
SPF
Eryfotona Actinica
Morning
SAR 429.81
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
SAR 245.95
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
SAR 187.00
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
SAR 848.48
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
SAR 157.51
-
Cleansing Mask
Goldfaden MD Facial Detox Mask
Once a week
SAR 328.29
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
SAR 17.19
-
Hydrating Toner
Alcohol-Free Toner
Morning · Once a week
SAR 97.00
-
Moisturizer
Hydro Boost+ Niacinamide Serum
Morning · Evening · Once a week
SAR 80.82
-
SPF
Clear Face Liquid Lotion Sunscreen
Morning
SAR 115.51
-
Pre-Cleanser
Oil-Free Eye Makeup Remover
Evening · Once a week
SAR 69.93
-
Cleansing Toner
Blackhead Eliminating Cleansing Toner
Evening
SAR 72.68
-
Serum or Treatment
Stubborn Marks PM Treatment
Evening · Once a week
SAR 97.00
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
SAR 157.51
-
Cleansing Mask
Clear Pore Cleanser/Mask
Once a week
SAR 103.58
Buy ISDIN routine · SAR 2,326.11 · 93% fit
Buy Neutrogena routine · SAR 811.22 · 70% fitSee multi-brand routine · 97% fit
Neutrogena vs ISDIN routines for combination skin
-
Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
SAR 191.00
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
SAR 166.90
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
SAR 39.70
-
SPF
Eryfotona Actinica
Morning
SAR 429.81
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
SAR 245.95
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
SAR 64.80
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
SAR 848.48
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
SAR 157.51
-
Cleansing Mask
KORA Organics Turmeric Brightening & Exfoliating Mask
Once a week
SAR 168.77
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
SAR 17.19
-
Hydrating Toner
Alcohol-Free Toner
Morning · Once a week
SAR 97.00
-
Moisturizer
Hydro Boost Hyaluronic Acid Serum
Morning · Evening · Once a week
SAR 150.91
-
SPF
Ultra Sheer Dry-Touch Sunscreen
Morning
SAR 51.99
-
Pre-Cleanser
Oil-Free Eye Makeup Remover
Evening · Once a week
SAR 69.93
-
Cleansing Toner
Blackhead Eliminating Cleansing Toner
Evening
SAR 72.68
-
Serum or Treatment
Stubborn Marks PM Treatment
Evening · Once a week
SAR 97.00
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
SAR 157.51
-
Cleansing Mask
Clear Pore Cleanser/Mask
Once a week
SAR 103.58
Buy ISDIN routine · SAR 2,312.92 · 93% fit
Buy Neutrogena routine · SAR 817.79 · 74% fitSee multi-brand routine · 97% fit
Questions and answers
Neutrogena or ISDIN: which is better?
ISDIN is the better choice for overall routine fit, as Lovi rates its routines as Superior across almost all skin types. Neutrogena offers strong options for skin with dark spots, mature skin, and acne-prone skin, but its routine fit is generally Average.
What is the difference between Neutrogena and ISDIN?
ISDIN achieves a Superior routine fit for dry skin, oily skin, combination skin, sensitive skin, dry sensitive skin, and oily acne-prone skin on the products on this page, while Neutrogena achieves an Average fit for those skin types. For skin texture improvement and anti-aging, Neutrogena does better.
Neutrogena or ISDIN for dry skin?
For dry skin, ISDIN is a Superior match, whereas Neutrogena has an Average routine fit among the products on this page. Hyaluronic acid helps provide deep hydration and moisture in both brands.
Dermatologic Therapy, 2022Journal of Pharmacy & Pharmaceutical Sciences, 2015
Neutrogena or ISDIN: which moisturizer is better?
ISDIN is the better choice for moisturizers, as Lovi rates its routines as Superior for dry skin compared to Neutrogena's Average fit level. ISDIN features lightweight moisturizers that help hydrate the skin effectively.
Which is more affordable, Neutrogena or ISDIN?
Neutrogena is more affordable than ISDIN, as ISDIN frequently receives negative reviews for its high price point.
Which brand has a better routine fit for dry sensitive skin?
ISDIN has a better routine fit for dry sensitive skin, offering a Superior level compared to Neutrogena's Average fit. The products on this page help provide deep hydration and gentle care.
Neutrogena or ISDIN for oily skin?
For oily skin, ISDIN is a Superior fit, whereas Neutrogena is Average. ISDIN helps provide lightweight sunscreens and moisturizers that suit oily skin.
Neutrogena or ISDIN: which sunscreen is better?
Both brands offer sunscreen options on this page, but ISDIN achieves a Superior routine fit for dry, sensitive, and combination skin while Neutrogena fits those skin types at an Average level. Retinol helps improve skin texture and reduce signs of aging.
The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007
Neutrogena or ISDIN for sensitive skin?
For sensitive skin, ISDIN is a better option because Lovi rates its routine as Superior, while Neutrogena rates Average. ISDIN features ultralight sunscreens and lightweight moisturizers that help soothe irritation without heavy scents.
Neutrogena or ISDIN for acne-prone skin?
Both brands fit acne-prone skin, with ISDIN achieving a Superior Lovi fit level and Neutrogena reaching High. The products on this page for both brands offer lightweight options that help manage breakouts while keeping skin comfortable.
Neutrogena or ISDIN for mature skin?
ISDIN is a better fit for mature skin, as Lovi rates its routine as Superior compared to Neutrogena's High fit level. Both brands include anti-aging ingredients, with Neutrogena featuring retinol which helps stimulate collagen accumulation in naturally aged skin.
Neutrogena or ISDIN for skin with dark spots?
Neutrogena has a High Lovi fit for skin with dark spots, while ISDIN also offers standout options like Eryfotona Actinica with a Superior Lovi fit. Neutrogena features targeted treatments with vitamin C and retinol, which helps reduce cutaneous pigmentation.
The Journal of Investigative Dermatology, 2000The British Journal of Dermatology, 2002
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)
Evaluation of moisturizing and irritation potential of sacha inchi oil
Solid lipid nanoparticles bearing oxybenzone: in-vitro and in-vivo evaluation
Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Functional properties and skin care effects of sodium trehalose sulfate
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-

Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.































































