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Neutrogena vs ISDIN

Neutrogena and ISDIN are well-regarded skincare brands offering thoughtfully formulated moisturizers, sunscreens, and cleansers enriched with beneficial ingredients. The American brand is widely loved for its gentle solutions featuring glycerin, hyaluronic acid, and dimethicone, which suit sensitive skin and dry skin best by respecting delicate moisture barriers. Conversely, the Spanish brand is appreciated for its elegant moisturizers, advanced sunscreens, restorative serums, and targeted eye products that similarly suit dry skin and sensitive skin best with dependable protection. While both cater to similar skin types, they differ in their foundational heritage, specific key ingredients, and distinct product lineups.

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

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ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

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This page compares some of the most popular Neutrogena and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

People Say

NeutrogenaISDIN
  • Lightweight and non-greasy texture Mostly MentionedMostly Mentioned
    • “absorbs instantly — ISDIN Eryfotona Actinica”
    • “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
    • “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
    • “Absorbs instantly without sticky residue — Neutrogena Hydro Boost Water Gel”
  • Deep hydration and moisture Mostly MentionedMostly Mentioned
    • “Skin looked plumper and radiant — Neutrogena HYDRO BOOST WATER CREAM”
    • “It also hydrates my skin. This cream has been so easy to add to my routine. — Neutrogena Retinol Regenerating Cream”
    • “Improved moisture and texture — ISDIN Hyaluronic Moisture”
    • “skin looks smooth and healthy — ISDIN K-Ox Eyes”
  • Sensitive skin friendly and gentle Mostly MentionedOften Mentioned
    • “leaves skin soft and balanced — Neutrogena Ultra Gentle Daily Cleanser”
    • “love that it has no scent — Neutrogena Ultra Gentle Daily Cleanser”
    • “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
    • “no excessive exfoliation — ISDIN Retinal Intense Serum”
  • Makeup compatibility and base Sometimes NotedOften Mentioned
    • “Foundation glides right over it — Neutrogena Hydro Boost Water Gel”
    • “Concealer doesn't cake or get stuck in crevices — Neutrogena Hydro Boost Eye Gel-Cream”
    • “acts like a primer — ISDIN Eryfotona Actinica”
    • “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
  • Skin texture improvement and anti-aging Sometimes NotedRarely Noted
    • “Skin is looking smoother — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
    • “Deep lines have softened — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
    • “I can see a difference in my forehead wrinkles. — Neutrogena Retinol Regenerating Cream”
    • “skin was much smoother — ISDIN Retinal Intense Serum”
  • Cooling and soothing sensation Rarely NotedSometimes Noted
    • “Feels amazing and cold on the skin — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
    • “Feels refreshing and cool on application — Neutrogena Hydro Boost Water Gel”
    • “applicator has a cooling effect — ISDIN K-Ox Eyes”
  • Price vs quantity and high cost Sometimes NotedOften Mentioned
    • “Jar is too small for the price — Neutrogena Hydro Boost Water Gel”
    • “Runs out quickly — Neutrogena HYDRO BOOST WATER CREAM”
    • “Tube is tiny for the cost — Neutrogena Hydro Boost Eye Gel-Cream”
    • “very expensive — ISDIN Eryfotona Actinica”
  • Strong fragrance and scent issues Sometimes NotedOften Mentioned
    • “Smell is too overpowering and lingering — Neutrogena Hydro Boost Water Gel”
    • “Scent is so off-putting — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
    • “smell is overpowering — ISDIN Eryfotona Actinica”
    • “lingering headache inducing effect — ISDIN K-Ox Eyes”
  • Packaging and design issues Sometimes NotedRarely Noted
    • “Pump stopped working — ISDIN Hyaluronic Concentrate”
    • “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
    • “Eye holes are too small — Neutrogena Hydro Boost Hydrating Hydrogel Mask”

Neutrogena vs ISDIN routines for dry skin

See multi-brand routine · 98% fit

Neutrogena vs ISDIN routines for oily skin

See multi-brand routine · 96% fit

Neutrogena vs ISDIN routines for combination skin

See multi-brand routine · 95% fit

Questions and answers

Neutrogena or ISDIN: which is better?

Both brands offer solid options, but ISDIN achieves a Superior routine fit for dry skin compared to Neutrogena at High. Reviewers note that ISDIN excels in providing ultralight sunscreens, while Neutrogena offers more anti-aging choices across the products on this page.

What is the difference between Neutrogena and ISDIN?

Neutrogena is an American brand founded in 1930, while ISDIN is a Spanish brand founded in 1975. Both brands offer products that fit dry, sensitive, and mature skin well, but ISDIN outperforms Neutrogena in routine fit levels across all skin types on this page.

Neutrogena or ISDIN for dry skin?

Both Neutrogena and ISDIN offer products on this page that help with dry skin, but ISDIN has a Superior Lovi fit level for dry skin compared to Neutrogena which has a High fit level. ISDIN's products on this page feature hydrating ingredients like hyaluronic acid, which helps improve skin quality and signs of aging.

Dermatologic Therapy, 2022

Neutrogena or ISDIN: which moisturizer is better?

Neutrogena offers deeply hydrating and lightweight moisturizers on this page that shoppers love, while ISDIN provides options like Hyaluronic Concentrate that help soothe sensitive skin. Retinol found in several moisturizers helps improve skin texture and reduce signs of aging.

The Journal of Investigative Dermatology, 2000Journal of Pharmacy & Pharmaceutical Sciences, 2015

Which is more affordable, Neutrogena or ISDIN?

Neutrogena is more affordable than ISDIN, as ISDIN reviewers frequently note a high price point while Neutrogena faces price concerns less often on the products on this page.

Which brand has more products listed on the page, Neutrogena or ISDIN?

Neutrogena has more products listed on the page, with thirty-nine products compared to eight products for ISDIN.

Which brand has better review themes for skin texture improvement and anti-aging?

Neutrogena has better review themes for skin texture improvement and anti-aging. The products on this page help deliver anti-aging benefits with ingredients like retinol.

The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007

How many ISDIN products list no fragrance compared to Neutrogena?

On the products on this page, 3 of 8 ISDIN products list no fragrance compared to 35 of 39 Neutrogena products.

Neutrogena or ISDIN for oily skin?

ISDIN is a better fit for oily skin, offering a Superior routine fit compared to Neutrogena's High fit on this page. The products on this page help provide lightweight hydration without a greasy feel, though reviewers note that ISDIN comes at a higher price point.

Neutrogena or ISDIN: which sunscreen is better?

Both brands offer top choices for sun protection, but ISDIN has Superior Lovi fit levels across a wider range of skin types on this page compared to Neutrogena. ISDIN is especially noted by reviewers for ultralight and makeup-friendly sunscreens, while Neutrogena provides budget-friendly options like the Ultra Sheer Dry-Touch Sunscreen.

Neutrogena or ISDIN for sensitive skin?

Both Neutrogena and ISDIN offer products that are well-suited for sensitive skin, with Lovi fit levels rated as High for both brands on this page. Reviewers note that both brands provide skin-friendly options, though Neutrogena features a broader range of products with no added fragrance across most of its line.

Neutrogena or ISDIN for acne-prone skin?

Neutrogena has a High routine fit for acne-prone skin, while ISDIN offers a Superior routine fit for acne-prone skin. Both brands provide lightweight moisturizers, but the products on this page show that ISDIN achieves higher overall fit levels for acne-prone skin.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.