Neutrogena vs ISDIN
Neutrogena and ISDIN are well-regarded skincare brands offering thoughtfully formulated moisturizers, sunscreens, and cleansers enriched with beneficial ingredients. The American brand is widely loved for its gentle solutions featuring glycerin, hyaluronic acid, and dimethicone, which suit sensitive skin and dry skin best by respecting delicate moisture barriers. Conversely, the Spanish brand is appreciated for its elegant moisturizers, advanced sunscreens, restorative serums, and targeted eye products that similarly suit dry skin and sensitive skin best with dependable protection. While both cater to similar skin types, they differ in their foundational heritage, specific key ingredients, and distinct product lineups.
Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.
investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
puig.combeautymatter.comuploads.puig.com
This page compares some of the most popular Neutrogena and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Neutrogena vs ISDIN products
People Say
Lightweight and non-greasy texture Mostly MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “Absorbs instantly without sticky residue — Neutrogena Hydro Boost Water Gel”
Deep hydration and moisture Mostly MentionedMostly Mentioned
- “Skin looked plumper and radiant — Neutrogena HYDRO BOOST WATER CREAM”
- “It also hydrates my skin. This cream has been so easy to add to my routine. — Neutrogena Retinol Regenerating Cream”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
Sensitive skin friendly and gentle Mostly MentionedOften Mentioned
- “leaves skin soft and balanced — Neutrogena Ultra Gentle Daily Cleanser”
- “love that it has no scent — Neutrogena Ultra Gentle Daily Cleanser”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Makeup compatibility and base Sometimes NotedOften Mentioned
- “Foundation glides right over it — Neutrogena Hydro Boost Water Gel”
- “Concealer doesn't cake or get stuck in crevices — Neutrogena Hydro Boost Eye Gel-Cream”
- “acts like a primer — ISDIN Eryfotona Actinica”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Skin texture improvement and anti-aging Sometimes NotedRarely Noted
- “Skin is looking smoother — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “Deep lines have softened — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “I can see a difference in my forehead wrinkles. — Neutrogena Retinol Regenerating Cream”
- “skin was much smoother — ISDIN Retinal Intense Serum”
Cooling and soothing sensation Rarely NotedSometimes Noted
- “Feels amazing and cold on the skin — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
- “Feels refreshing and cool on application — Neutrogena Hydro Boost Water Gel”
- “applicator has a cooling effect — ISDIN K-Ox Eyes”
Price vs quantity and high cost Sometimes NotedOften Mentioned
- “Jar is too small for the price — Neutrogena Hydro Boost Water Gel”
- “Runs out quickly — Neutrogena HYDRO BOOST WATER CREAM”
- “Tube is tiny for the cost — Neutrogena Hydro Boost Eye Gel-Cream”
- “very expensive — ISDIN Eryfotona Actinica”
Strong fragrance and scent issues Sometimes NotedOften Mentioned
- “Smell is too overpowering and lingering — Neutrogena Hydro Boost Water Gel”
- “Scent is so off-putting — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “smell is overpowering — ISDIN Eryfotona Actinica”
- “lingering headache inducing effect — ISDIN K-Ox Eyes”
Packaging and design issues Sometimes NotedRarely Noted
- “Pump stopped working — ISDIN Hyaluronic Concentrate”
- “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
- “Eye holes are too small — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
Neutrogena vs ISDIN routines for dry skin
-
Cleanser
CeraVe Hydrating Facial Cleanser
Morning · Evening · Once a week
€14.68
-
Hydrating Toner
COSRX Propolis Synergy Toner
Morning
€14.28
-
Moisturizer
Elizabeth Arden Advanced Ceramide Lift and Firm Night Cream
Morning · Evening · Once a week
€50.82
-
SPF
Fusion Water
Morning
€23.00
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€16.25
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€47.00
-
Nourishing Mask
Mediheal Watermide Essential Mask
Once a week
€28.40
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
€10.11
-
Hydrating Toner
COSRX Propolis Synergy Toner
Morning
€14.28
-
Moisturizer
Hydro Boost Hyaluronic Acid Serum
Morning · Evening · Once a week
€18.68
-
SPF
Clear Face Liquid Lotion Sunscreen
Morning
€23.70
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
€8.65
-
Serum or Treatment
Beauty of Joseon Propolis + Niacinamide Glow Serum
Evening · Once a week
€14.94
-
Nourishing Mask
Mediheal Watermide Essential Mask
Once a week
€28.40
Neutrogena vs ISDIN routines for oily skin
-
Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
€21.45
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€19.99
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
€16.50
-
SPF
Eryfotona Actinica
Morning
€34.93
-
Pre-Cleanser
Pyunkang Yul Deep Cleansing Oil
Evening · Once a week
€22.67
-
Cleansing Toner
Pixi Glow Tonic
Evening
€34.00
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€47.00
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€76.00
-
Cleansing Mask
Dr. Sebagh Deep Exfoliating Mask
Once a week
€82.85
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
€10.11
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€19.99
-
Moisturizer
Hydro Boost+ Niacinamide Serum
Morning · Evening · Once a week
€12.59
-
SPF
Clear Face Liquid Lotion Sunscreen
Morning
€23.70
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
€8.65
-
Cleansing Toner
Blackhead Eliminating Cleansing Toner
Evening
€9.99
-
Serum or Treatment
The Ordinary Niacinamide 10% + Zinc 1%
Evening · Once a week
€8.99
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€76.00
-
Cleansing Mask
Clear Pore Cleanser/Mask
Once a week
€10.46
Neutrogena vs ISDIN routines for combination skin
-
Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
€56.86
-
Hydrating Toner
La Mer The Tonic
Morning · Once a week
€115.30
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
€16.50
-
SPF
Eryfotona Actinica
Morning
€34.93
-
Pre-Cleanser
Pyunkang Yul Deep Cleansing Oil
Evening · Once a week
€22.67
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€22.99
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€47.00
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€76.00
-
Cleansing Mask
Sand & Sky Australian Pink Clay Porefining Face Mask
Once a week
€48.22
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
€10.11
-
Hydrating Toner
La Mer The Tonic
Morning · Once a week
€115.30
-
Moisturizer
Hydro Boost Hyaluronic Acid Serum
Morning · Evening · Once a week
€18.68
-
SPF
Ultra Sheer Dry-Touch Sunscreen
Morning
€24.99
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
€8.65
-
Cleansing Toner
Blackhead Eliminating Cleansing Toner
Evening
€9.99
-
Serum or Treatment
Beauty of Joseon Propolis + Niacinamide Glow Serum
Evening · Once a week
€14.94
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€76.00
-
Cleansing Mask
Clear Pore Cleanser/Mask
Once a week
€10.46
Questions and answers
Neutrogena or ISDIN: which is better?
Both brands offer solid options, but ISDIN achieves a Superior routine fit for dry skin compared to Neutrogena at High. Reviewers note that ISDIN excels in providing ultralight sunscreens, while Neutrogena offers more anti-aging choices across the products on this page.
What is the difference between Neutrogena and ISDIN?
Neutrogena is an American brand founded in 1930, while ISDIN is a Spanish brand founded in 1975. Both brands offer products that fit dry, sensitive, and mature skin well, but ISDIN outperforms Neutrogena in routine fit levels across all skin types on this page.
Neutrogena or ISDIN for dry skin?
Both Neutrogena and ISDIN offer products on this page that help with dry skin, but ISDIN has a Superior Lovi fit level for dry skin compared to Neutrogena which has a High fit level. ISDIN's products on this page feature hydrating ingredients like hyaluronic acid, which helps improve skin quality and signs of aging.
Neutrogena or ISDIN: which moisturizer is better?
Neutrogena offers deeply hydrating and lightweight moisturizers on this page that shoppers love, while ISDIN provides options like Hyaluronic Concentrate that help soothe sensitive skin. Retinol found in several moisturizers helps improve skin texture and reduce signs of aging.
The Journal of Investigative Dermatology, 2000Journal of Pharmacy & Pharmaceutical Sciences, 2015
Which is more affordable, Neutrogena or ISDIN?
Neutrogena is more affordable than ISDIN, as ISDIN reviewers frequently note a high price point while Neutrogena faces price concerns less often on the products on this page.
Which brand has more products listed on the page, Neutrogena or ISDIN?
Neutrogena has more products listed on the page, with thirty-nine products compared to eight products for ISDIN.
Which brand has better review themes for skin texture improvement and anti-aging?
Neutrogena has better review themes for skin texture improvement and anti-aging. The products on this page help deliver anti-aging benefits with ingredients like retinol.
The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007
How many ISDIN products list no fragrance compared to Neutrogena?
On the products on this page, 3 of 8 ISDIN products list no fragrance compared to 35 of 39 Neutrogena products.
Neutrogena or ISDIN for oily skin?
ISDIN is a better fit for oily skin, offering a Superior routine fit compared to Neutrogena's High fit on this page. The products on this page help provide lightweight hydration without a greasy feel, though reviewers note that ISDIN comes at a higher price point.
Neutrogena or ISDIN: which sunscreen is better?
Both brands offer top choices for sun protection, but ISDIN has Superior Lovi fit levels across a wider range of skin types on this page compared to Neutrogena. ISDIN is especially noted by reviewers for ultralight and makeup-friendly sunscreens, while Neutrogena provides budget-friendly options like the Ultra Sheer Dry-Touch Sunscreen.
Neutrogena or ISDIN for sensitive skin?
Both Neutrogena and ISDIN offer products that are well-suited for sensitive skin, with Lovi fit levels rated as High for both brands on this page. Reviewers note that both brands provide skin-friendly options, though Neutrogena features a broader range of products with no added fragrance across most of its line.
Neutrogena or ISDIN for acne-prone skin?
Neutrogena has a High routine fit for acne-prone skin, while ISDIN offers a Superior routine fit for acne-prone skin. Both brands provide lightweight moisturizers, but the products on this page show that ISDIN achieves higher overall fit levels for acne-prone skin.
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)
Evaluation of moisturizing and irritation potential of sacha inchi oil
Solid lipid nanoparticles bearing oxybenzone: in-vitro and in-vivo evaluation
Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Functional properties and skin care effects of sodium trehalose sulfate
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-

Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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