Medicube vs ISDIN
Medicube and ISDIN are established skincare brands offering curated selections of moisturizers, serums, toners, masks, and eye products crafted with key ingredients like niacinamide, collagen, and hyaluronic acid. Founded in 2016 by APR Corp., Medicube suits oily and acne-prone skin best with standout solutions such as the AGE-R Booster Gel, Deep Peptide Radiance Mask, and Deep Lifting Peptide Eye Cream, balancing excess sebum and hydration. Founded in 1975 by Puig, ISDIN suits sensitive and acne-prone skin best with gentle creations like Fusion Water, Eryfotona Actinica, and K-Ox Eyes that respect delicate moisture barriers. Ultimately, both brands differ through their distinct formulations and geographic origins, as the Korean brand addresses hyperpigmentation and aging signs, while the Spanish brand delivers reliable daily sun and barrier protection.
Medicube is a Korean skincare brand founded in 2016 and owned by APR Corp..
medicubereviews.co.ukglossy.co
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
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This page compares some of the most popular Medicube and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Medicube vs ISDIN products
People Say
Hydration and Moisture Mostly MentionedMostly Mentioned
- “skin feels bouncier and hydrated — Medicube PDRN Pink Peptide Serum”
- “glass skin — Medicube PDRN Pink Collagen Gel Mask”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Lightweight and Non-Greasy Texture Not notedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
Skin Texture and Smoothing Often MentionedOften Mentioned
- “gives my skin a smooth, glass-like finish — Medicube Zero Pore Pad”
- “skin feels smoother — Medicube PDRN Pink Peptide Serum”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
- “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum”
Glow and Brightening Often MentionedSometimes Noted
- “gave me instant glass skin — Medicube Collagen Jelly Cream”
- “woke up with glowing skin — Medicube Collagen Night Wrapping Mask”
- “Dark spots go away faster — Medicube Deep Vita C Pad”
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
Acne and Pore Care Often MentionedNot noted
- “Pores drastically reduced — Medicube Zero Foam Cleanser”
- “Removes every trace of oil — Medicube Red Foam Cleanser”
- “noticed a real difference in pore visibility — Medicube Zero Pore Pad”
High Price Point Sometimes NotedOften Mentioned
- “tube is tiny for the price — Medicube Collagen Night Wrapping Mask”
- “price is steep — Medicube PDRN Pink Collagen Gel Mask”
- “price is a bit steep — Medicube Red Succinic Acid Peeling Pad”
- “very expensive — ISDIN Eryfotona Actinica”
Strong Fragrance and Scent Often MentionedOften Mentioned
- “slightly fishy smell — Medicube PDRN Pink Peptide Serum”
- “smells like old lady perfume — Medicube Collagen Jelly Cream”
- “smell is overpowering — ISDIN Eryfotona Actinica”
- “lingering headache inducing effect — ISDIN K-Ox Eyes”
Packaging and Application Issues Sometimes NotedSometimes Noted
- “Pump stopped working — ISDIN Hyaluronic Concentrate”
- “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
- “Pilled up on my skin — ISDIN Hyaluronic Moisture”
- “messy — Medicube PDRN Pink Collagen Gel Mask”
Medicube vs ISDIN routines for dry skin
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Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
SAR 297.00
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Moisturizer
SKIN1004 Madagascar Centella Probio-Cica Enrich Cream
Morning · Evening · Once a week
SAR 48.00
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SPF
Fusion Water
Morning
SAR 75.00
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
SAR 65.11
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Cleansing Toner
ROUND LAB 1025 Dokdo Cleansing Water
Evening
SAR 72.64
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Serum or Treatment
Flavo-C Serum
Evening · Once a week
SAR 848.48
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Enzyme Powder
FANCL Facial Washing Powder
Once a week
SAR 130.30
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Nourishing Mask
Mediheal Watermide Essential Mask
Once a week
SAR 234.73
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Cleanser
Zero Foam Cleanser
Morning · Evening · Once a week
SAR 40.90
-
Hydrating Toner
Triple Collagen Toner
Morning
SAR 50.00
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
SAR 117.99
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SPF
d'Alba Piedmont Waterfull Mild Sunscreen
Morning
SAR 75.00
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
SAR 65.11
-
Cleansing Toner
Zero Pore Pad
Evening
SAR 64.80
-
Serum or Treatment
One Day Exosome Shot 2000
Evening · Once a week
SAR 34.00
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Enzyme Powder
FANCL Facial Washing Powder
Once a week
SAR 130.30
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Nourishing Mask
Deep Peptide Radiance Mask
Once a week
SAR 120.88
Buy ISDIN routine · SAR 1,771.26 · 92% fit
Buy Medicube routine · SAR 698.98 · 86% fitSee multi-brand routine · 96% fit
Medicube vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
SAR 36.33
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
SAR 53.04
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
SAR 39.70
-
SPF
Eryfotona Actinica
Morning
SAR 429.81
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
SAR 245.95
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
SAR 187.00
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
SAR 848.48
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
SAR 157.51
-
Cleansing Mask
Goldfaden MD Facial Detox Mask
Once a week
SAR 328.29
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Cleanser
Red Foam Cleanser
Morning · Evening · Once a week
SAR 35.61
-
Hydrating Toner
Triple Collagen Toner
Morning · Once a week
SAR 50.00
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
SAR 117.99
-
SPF
CeraVe AM Facial Moisturizing Lotion SPF 30
Morning
SAR 46.95
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
SAR 245.95
-
Cleansing Toner
Zero Pore Pad
Evening
SAR 64.80
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
SAR 157.51
-
Cleansing Mask
Zero Pore Blackhead Mud Mask
Once a week
SAR 87.59
Buy ISDIN routine · SAR 2,326.11 · 93% fit
Buy Medicube routine · SAR 806.40 · 88% fitSee multi-brand routine · 97% fit
Medicube vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
SAR 191.00
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
SAR 166.90
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
SAR 39.70
-
SPF
Eryfotona Actinica
Morning
SAR 429.81
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
SAR 245.95
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
SAR 64.80
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
SAR 848.48
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
SAR 157.51
-
Cleansing Mask
KORA Organics Turmeric Brightening & Exfoliating Mask
Once a week
SAR 168.77
-
Cleanser
Red Foam Cleanser
Morning · Evening · Once a week
SAR 35.61
-
Hydrating Toner
Triple Collagen Toner
Morning · Once a week
SAR 50.00
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
SAR 117.99
-
SPF
CeraVe AM Facial Moisturizing Lotion SPF 30
Morning
SAR 46.95
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
SAR 245.95
-
Cleansing Toner
Zero Pore Pad
Evening
SAR 64.80
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
SAR 157.51
-
Cleansing Mask
Zero Pore Blackhead Mud Mask
Once a week
SAR 87.59
Buy ISDIN routine · SAR 2,312.92 · 93% fit
Buy Medicube routine · SAR 806.40 · 88% fitSee multi-brand routine · 97% fit
Questions and answers
Medicube or ISDIN: which is better?
Both brands are great, but ISDIN has a superior routine fit across skin types and excels in lightweight textures. Medicube is better for glow and acne care, though it has more fragrance-free options since only 2 out of 25 products contain fragrance compared to 5 out of 8 for ISDIN.
What is the difference between Medicube and ISDIN?
Medicube is a South Korean skincare brand focused on hydration, glow, and pore care with fragrance-free options across most of its products, while ISDIN is a Spanish brand known for ultralight, makeup-friendly sunscreens with high price points. Lovi gives both brands High to Superior fit levels across all skin types, though ISDIN performs better in routine fits for dry, oily, and sensitive skin.
Medicube or ISDIN for dry skin?
Both Medicube and ISDIN fit dry skin well, with ISDIN achieving a Superior routine fit and Medicube reaching High. Hyaluronic acid helps maintain dry skin hydration and improve signs of aging.
Medicube or ISDIN: which moisturizer is better?
Both brands offer moisturizers, but ISDIN generally stands out for lightweight hydration while Medicube is known for deep moisture. The products on this page help improve skin quality and hydration.
Which is more affordable, Medicube or ISDIN?
Medicube is more affordable, though both brands face pricing concerns from reviewers. Reviewers on this page frequently mention a high price point for both Medicube and ISDIN.
Between Medicube and ISDIN, which brand offers better results for glow and brightening?
Medicube offers better results for glow and brightening compared to ISDIN. Review themes show that Medicube does better for glow and brightening, utilizing key ingredients like niacinamide which helps reduce cutaneous pigmentation.
How do the founding years and corporate owners of Medicube and ISDIN compare?
Medicube was founded in 2016 in South Korea and is owned by APR Corp., while ISDIN was founded in 1975 in Spain and is owned by Puig.
Which brand has more products listed without fragrance, Medicube or ISDIN?
Medicube has more products listed without fragrance, as 23 of its 25 products on this page list no fragrance compared to only 3 of the 8 ISDIN products.
Medicube or ISDIN for oily skin?
Both brands fit oily skin well, but ISDIN has a superior routine fit compared to Medicube's high fit. ISDIN stands out for its ultralight sunscreens and lightweight moisturizers, whereas Medicube offers strong options for acne and pore care.
Medicube or ISDIN for sensitive skin?
Medicube is a good choice for sensitive skin because the products on this page have a High fit for sensitive skin, and 23 of 25 products list no fragrance. ISDIN also fits sensitive skin well, with Lovi giving its routine a Superior fit for sensitive skin.
Medicube or ISDIN for acne-prone skin?
Medicube fits acne-prone skin with a High routine rating, whereas ISDIN reaches a Superior routine rating for this skin type. Both brands feature effective options, but Medicube is specifically noted for strong acne and pore care performance.
Research behind their key ingredients
Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Effect of Camellia japonica oil on human type I procollagen production and skin barrier function
Protective effects of Camellia japonica flower extract against urban air pollutants
Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Functional properties and skin care effects of sodium trehalose sulfate
Composition characterization and clinical efficacy study of a salmon egg extract
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from Paeonia lactiflora
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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