Neutrogena vs ISDIN
Neutrogena and ISDIN are established skincare brands from America and Spain, respectively. Both offer thoughtful arrays of moisturizers, sunscreens, and cleansers that suit sensitive skin, while the former features gentle ingredients like glycerin, hyaluronic acid, and dimethicone for mature skin, and the latter relies on meticulously engineered formulas for oily, acne-prone skin. Users choose between them by weighing the American brand's scientifically backed hydration and barrier restoration against the Spanish brand's sophisticated compositions and daily protection.
Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.
investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
puig.combeautymatter.comuploads.puig.com
This page compares some of the most popular Neutrogena and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Neutrogena vs ISDIN products
People Say
Lightweight and non-greasy texture Mostly MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “Absorbs instantly without sticky residue — Neutrogena Hydro Boost Water Gel”
Deep hydration and moisture Mostly MentionedMostly Mentioned
- “Skin looked plumper and radiant — Neutrogena HYDRO BOOST WATER CREAM”
- “It also hydrates my skin. This cream has been so easy to add to my routine. — Neutrogena Retinol Regenerating Cream”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
Sensitive skin friendly and gentle Mostly MentionedOften Mentioned
- “leaves skin soft and balanced — Neutrogena Ultra Gentle Daily Cleanser”
- “love that it has no scent — Neutrogena Ultra Gentle Daily Cleanser”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Makeup compatibility and base Sometimes NotedOften Mentioned
- “Foundation glides right over it — Neutrogena Hydro Boost Water Gel”
- “Concealer doesn't cake or get stuck in crevices — Neutrogena Hydro Boost Eye Gel-Cream”
- “acts like a primer — ISDIN Eryfotona Actinica”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Skin texture improvement and anti-aging Sometimes NotedRarely Noted
- “Skin is looking smoother — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “Deep lines have softened — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “I can see a difference in my forehead wrinkles. — Neutrogena Retinol Regenerating Cream”
- “skin was much smoother — ISDIN Retinal Intense Serum”
Cooling and soothing sensation Rarely NotedSometimes Noted
- “Feels amazing and cold on the skin — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
- “Feels refreshing and cool on application — Neutrogena Hydro Boost Water Gel”
- “applicator has a cooling effect — ISDIN K-Ox Eyes”
Price vs quantity and high cost Sometimes NotedOften Mentioned
- “Jar is too small for the price — Neutrogena Hydro Boost Water Gel”
- “Runs out quickly — Neutrogena HYDRO BOOST WATER CREAM”
- “Tube is tiny for the cost — Neutrogena Hydro Boost Eye Gel-Cream”
- “very expensive — ISDIN Eryfotona Actinica”
Strong fragrance and scent issues Sometimes NotedOften Mentioned
- “Smell is too overpowering and lingering — Neutrogena Hydro Boost Water Gel”
- “Scent is so off-putting — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “smell is overpowering — ISDIN Eryfotona Actinica”
- “lingering headache inducing effect — ISDIN K-Ox Eyes”
Packaging and design issues Sometimes NotedRarely Noted
- “Pump stopped working — ISDIN Hyaluronic Concentrate”
- “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
- “Eye holes are too small — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
Neutrogena vs ISDIN routines for dry skin
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Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
A$26.59
-
Hydrating Toner
Pyunkang Yul Calming Deep Moisture Toner
Morning
A$23.99
-
Moisturizer
d'Alba First Spray Serum
Morning · Evening · Once a week
A$26.09
-
SPF
Bioderma Photoderm Mineral Fluide SPF50+
Morning
A$24.49
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
A$27.35
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
A$30.99
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
A$28.48
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
A$18.99
-
Hydrating Toner
Alcohol-Free Toner
Morning
A$8.49
-
Moisturizer
Hydro Boost Hyaluronic Acid Serum
Morning · Evening · Once a week
A$18.99
-
SPF
Ultra Sheer Dry-Touch Sunscreen
Morning
A$12.99
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
A$18.99
-
Serum or Treatment
Beauty of Joseon Propolis + Niacinamide Glow Serum
Evening · Once a week
A$16.95
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Nourishing Mask
Hydro Boost Hydrating Hydrogel Mask
Once a week
A$4.49
Buy ISDIN routine · A$223.48 · 94% fit
Buy Neutrogena routine · A$116.40 · 81% fitSee multi-brand routine · 97% fit
Neutrogena vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
A$13.99
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
A$34.66
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
A$22.99
-
SPF
La Roche-Posay Anthelios Clear Skin Dry Touch Sunscreen SPF 60
Morning
A$27.99
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
A$80.43
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
A$75.95
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
A$30.99
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
A$118.35
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
A$18.99
-
Hydrating Toner
Alcohol-Free Toner
Morning · Once a week
A$8.49
-
Moisturizer
Hydro Boost+ Niacinamide Serum
Morning · Evening · Once a week
A$22.49
-
SPF
Ultra Sheer Dry-Touch Sunscreen
Morning
A$12.99
-
Pre-Cleanser
Oil-Free Eye Makeup Remover
Evening · Once a week
A$10.49
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
A$75.95
-
Serum or Treatment
Beauty of Joseon Propolis + Niacinamide Glow Serum
Evening · Once a week
A$16.95
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Cleansing Mask
Clear Pore Cleanser/Mask
Once a week
A$42.95
Buy ISDIN routine · A$440.85 · 94% fit
Buy Neutrogena routine · A$244.80 · 75% fitSee multi-brand routine · 96% fit
Neutrogena vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
A$73.61
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
A$42.00
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
A$22.99
-
Pre-Cleanser
Pyunkang Yul Deep Cleansing Oil
Evening · Once a week
A$30.99
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
A$29.90
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
A$30.99
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
A$118.35
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
A$18.99
-
Hydrating Toner
Alcohol-Free Toner
Morning · Once a week
A$8.49
-
Moisturizer
Hydro Boost Hyaluronic Acid Serum
Morning · Evening · Once a week
A$18.99
-
SPF
Ultra Sheer Dry-Touch Sunscreen
Morning
A$12.99
-
Pre-Cleanser
Oil-Free Eye Makeup Remover
Evening · Once a week
A$10.49
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
A$29.90
-
Serum or Treatment
Beauty of Joseon Propolis + Niacinamide Glow Serum
Evening · Once a week
A$16.95
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Cleansing Mask
Clear Pore Cleanser/Mask
Once a week
A$42.95
Buy ISDIN routine · A$384.33 · 93% fit
Buy Neutrogena routine · A$195.25 · 80% fitSee multi-brand routine · 95% fit
Questions and answers
Neutrogena or ISDIN: which is better?
Both brands offer solid options, but ISDIN generally achieves a Superior routine fit across skin types compared to Neutrogena's High fit. Retinol helps improve skin texture and reduce signs of aging in formulas on these pages.
The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007
What is the difference between Neutrogena and ISDIN?
Neutrogena is an American brand founded in 1930 that offers a wide range of products with Lovi fit levels generally reaching High or Superior for most skin types, while ISDIN is a Spanish brand founded in 1975 that provides sunscreens and serums like Eryfotona Actinica and Flavo-C Serum. Reviewers note that ISDIN excels in ultralight textures, whereas Neutrogena is often chosen for skin texture improvement and anti-aging benefits using ingredients like retinol which helps stimulate collagen accumulation in naturally aged skin.
Neutrogena or ISDIN for dry skin?
ISDIN is a better fit for dry skin, offering a Superior routine fit compared to Neutrogena's High fit on this page. Ingredients like hyaluronic acid found in these products help provide deep hydration and improve skin quality.
Journal of Pharmacy & Pharmaceutical Sciences, 2015Dermatologic Therapy, 2022
Neutrogena or ISDIN: which moisturizer is better?
Neutrogena is better for deep hydration and anti-aging routines, whereas ISDIN is better for lightweight textures and superior dry skin routine fit. Both brands offer products with hyaluronic acid, which helps retain skin moisture.
Journal of Pharmacy & Pharmaceutical Sciences, 2015Dermatologic Therapy, 2022
Which is more affordable, Neutrogena or ISDIN?
Neutrogena is more affordable, as ISDIN is often noted by reviewers for having a high price point. Neutrogena is also mentioned for price versus quantity and high cost concerns.
Which brand has more fragrance-free products, Neutrogena or ISDIN?
Neutrogena has more fragrance-free products than ISDIN, with 35 of 39 products on this page listing no fragrance compared to 3 of 8 for ISDIN.
How do the founding years and current ownership of Neutrogena and ISDIN compare?
Neutrogena was founded in the United States in 1930 and is owned by Kimberly-Clark Corporation since 2026, while ISDIN was founded in Spain in 1975 and is owned by Puig.
Which brand performs better for skin texture improvement and anti-aging according to reviewers?
Neutrogena performs better for skin texture improvement and anti-aging according to reviewers. Retinol helps stimulate collagen accumulation in naturally aged human skin.
The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007
Neutrogena or ISDIN for oily skin?
ISDIN is a better fit for oily skin, with a routine fit of Superior compared to Neutrogena's High. Reviewers note that ISDIN excels particularly in providing ultralight sunscreens.
Neutrogena or ISDIN: which sunscreen is better?
Both brands offer solid sunscreen options, but ISDIN stands out with Superior Lovi fit levels for dry and dry sensitive skin on products like Eryfotona Actinica. Neutrogena sunscreens such as Ultra Sheer Dry-Touch Sunscreen and Clear Face Liquid Lotion Sunscreen also provide Superior fit levels for sensitive, combination, and oily skin types.
Neutrogena or ISDIN for sensitive skin?
Both Neutrogena and ISDIN offer products on this page with a High Lovi fit level for sensitive skin. Neutrogena is well-suited for sensitive skin due to its gentle formulations, while ISDIN provides ultralight sunscreens and lightweight moisturizers that are skin-friendly.
Neutrogena or ISDIN for acne-prone skin?
Both Neutrogena and ISDIN offer products on this page that are a High fit for acne-prone skin. Retinol helps improve skin texture and supports collagen accumulation in aged skin.
The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)
Evaluation of moisturizing and irritation potential of sacha inchi oil
Solid lipid nanoparticles bearing oxybenzone: in-vitro and in-vivo evaluation
Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Functional properties and skin care effects of sodium trehalose sulfate
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-

Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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