Neutrogena vs ISDIN
Neutrogena and ISDIN are well-regarded skincare brands offering reliable daily essentials and advanced treatments for diverse complexions. The American brand, founded in 1930, is widely loved for its thoughtful array of moisturizers, sunscreens, cleansers, and toners relying on glycerin, hyaluronic acid, and dimethicone, which suit dry skin and mature skin best. Meanwhile, the Spanish counterpart, founded in 1975, is beloved for its sophisticated moisturizers, advanced sunscreens, targeted serums, and soothing eye products tailored primarily for dry skin and combination skin. While both companies excel in hydration and sun protection, they differ in their origin, founding eras, and specific active formulations designed to target unique dermatological concerns.
Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.
investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
puig.combeautymatter.comuploads.puig.com
This page compares some of the most popular Neutrogena and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Neutrogena vs ISDIN products
People Say
Lightweight and non-greasy texture Mostly MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “Absorbs instantly without sticky residue — Neutrogena Hydro Boost Water Gel”
Deep hydration and moisture Mostly MentionedMostly Mentioned
- “Skin looked plumper and radiant — Neutrogena HYDRO BOOST WATER CREAM”
- “It also hydrates my skin. This cream has been so easy to add to my routine. — Neutrogena Retinol Regenerating Cream”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
Sensitive skin friendly and gentle Mostly MentionedOften Mentioned
- “leaves skin soft and balanced — Neutrogena Ultra Gentle Daily Cleanser”
- “love that it has no scent — Neutrogena Ultra Gentle Daily Cleanser”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Makeup compatibility and base Sometimes NotedOften Mentioned
- “Foundation glides right over it — Neutrogena Hydro Boost Water Gel”
- “Concealer doesn't cake or get stuck in crevices — Neutrogena Hydro Boost Eye Gel-Cream”
- “acts like a primer — ISDIN Eryfotona Actinica”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Skin texture improvement and anti-aging Sometimes NotedRarely Noted
- “Skin is looking smoother — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “Deep lines have softened — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “I can see a difference in my forehead wrinkles. — Neutrogena Retinol Regenerating Cream”
- “skin was much smoother — ISDIN Retinal Intense Serum”
Cooling and soothing sensation Rarely NotedSometimes Noted
- “Feels amazing and cold on the skin — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
- “Feels refreshing and cool on application — Neutrogena Hydro Boost Water Gel”
- “applicator has a cooling effect — ISDIN K-Ox Eyes”
Price vs quantity and high cost Sometimes NotedOften Mentioned
- “Jar is too small for the price — Neutrogena Hydro Boost Water Gel”
- “Runs out quickly — Neutrogena HYDRO BOOST WATER CREAM”
- “Tube is tiny for the cost — Neutrogena Hydro Boost Eye Gel-Cream”
- “very expensive — ISDIN Eryfotona Actinica”
Strong fragrance and scent issues Sometimes NotedOften Mentioned
- “Smell is too overpowering and lingering — Neutrogena Hydro Boost Water Gel”
- “Scent is so off-putting — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “smell is overpowering — ISDIN Eryfotona Actinica”
- “lingering headache inducing effect — ISDIN K-Ox Eyes”
Packaging and design issues Sometimes NotedRarely Noted
- “Pump stopped working — ISDIN Hyaluronic Concentrate”
- “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
- “Eye holes are too small — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
Neutrogena vs ISDIN routines for dry skin
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Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
€19.75
-
Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
€12.59
-
Moisturizer
d'Alba First Spray Serum
Morning · Evening · Once a week
€16.99
-
SPF
Fusion Water
Morning
€25.99
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€10.97
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
€19.00
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
€8.61
-
Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
€12.59
-
Moisturizer
Hydro Boost Hyaluronic Acid Serum
Morning · Evening · Once a week
€8.83
-
SPF
Ultra Sheer Dry-Touch Sunscreen
Morning
€12.95
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
€7.99
-
Serum or Treatment
Beauty of Joseon Propolis + Niacinamide Glow Serum
Evening · Once a week
€9.99
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
€19.00
Neutrogena vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
€11.75
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€16.59
-
Moisturizer
CeraVe PM Facial Moisturizing Lotion
Morning · Evening · Once a week
€38.99
-
SPF
Eryfotona Actinica
Morning
€32.49
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€104.00
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
€16.90
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Dr. Sebagh Deep Exfoliating Mask
Once a week
€81.80
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
€8.61
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€16.59
-
Moisturizer
Hydro Boost+ Niacinamide Serum
Morning · Evening · Once a week
€10.49
-
SPF
Ultra Sheer Dry-Touch Sunscreen
Morning
€12.95
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
€7.99
-
Cleansing Toner
Blackhead Eliminating Cleansing Toner
Evening
€3.95
-
Serum or Treatment
The Ordinary Niacinamide 10% + Zinc 1%
Evening · Once a week
€5.80
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Clear Pore Cleanser/Mask
Once a week
€3.95
Neutrogena vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
€39.99
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Some By Mi Yuja Niacin Brightening Moisture Gel Cream
Morning · Evening · Once a week
€13.67
-
SPF
Eryfotona Actinica
Morning
€32.49
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€104.00
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€16.98
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Origins Original Skin Retexturizing Mask with Rose Clay
Once a week
€28.50
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
€8.61
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Hydro Boost Hyaluronic Acid Serum
Morning · Evening · Once a week
€8.83
-
SPF
Ultra Sheer Dry-Touch Sunscreen
Morning
€12.95
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
€7.99
-
Cleansing Toner
Blackhead Eliminating Cleansing Toner
Evening
€3.95
-
Serum or Treatment
Beauty of Joseon Propolis + Niacinamide Glow Serum
Evening · Once a week
€9.99
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Clear Pore Cleanser/Mask
Once a week
€3.95
Questions and answers
Neutrogena or ISDIN: which is better?
ISDIN achieves a Superior routine fit for dry sensitive skin, whereas Neutrogena reaches an Average fit for that skin type. For all other skin types, both brands achieve a High routine fit.
What is the difference between Neutrogena and ISDIN?
Neutrogena is a US-founded brand owned by Kimberly-Clark Corporation since 2026, offering a wide range of products with lower fragrance rates, whereas ISDIN is a Spanish brand founded in 1975 and owned by Puig. Lovi shows that the products on this page for ISDIN achieve Superior routine fit levels for dry sensitive skin, while Neutrogena achieves an Average fit level for that skin type.
Neutrogena or ISDIN for dry skin?
ISDIN has a Superior Lovi fit level for dry skin, whereas Neutrogena has a High routine fit. Both brands offer hydrating moisturizers, but ISDIN is frequently praised for its lightweight texture.
Neutrogena or ISDIN: which moisturizer is better?
Neutrogena offers deeply hydrating and lightweight moisturizers that are well-liked for anti-aging and acne-safe care, with the products on this page achieving High fit levels for dry and mature skin types. ISDIN also provides lightweight moisturizers, though reviewers note a higher price point for the brand. Retinol and hyaluronic acid help improve skin texture and moisture.
The Journal of Investigative Dermatology, 2000Journal of Pharmacy & Pharmaceutical Sciences, 2015
Which is more affordable, Neutrogena or ISDIN?
Neutrogena is more affordable, as ISDIN has a high price point that reviewers often note. Both brands offer lightweight moisturizers, but Neutrogena products on this page are generally less expensive.
Neutrogena or ISDIN: which has better routine fit for dry sensitive skin?
ISDIN is the better choice for dry sensitive skin, as Lovi rates its routine fit as Superior while Neutrogena rates it as Average. Both brands offer products with hydrating ingredients like hyaluronic acid, which helps improve skin moisture and barrier function.
Journal of Pharmacy & Pharmaceutical Sciences, 2015Dermatologic Therapy, 2022
Which brand has more fragrance-free products, Neutrogena or ISDIN?
Neutrogena has more fragrance-free products on this page, with thirty-nine products compared to ISDIN's eight.
Neutrogena or ISDIN: which is better for skin texture improvement and anti-aging?
Neutrogena does better for skin texture improvement and anti-aging according to the review themes on this page. Ingredients like retinol help improve the appearance of aging skin and stimulate collagen accumulation.
The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007
Neutrogena or ISDIN for oily skin?
Both brands offer solid options for oily skin, with Lovi giving Neutrogena a High fit and ISDIN a Superior fit. The products on this page from ISDIN are noted more often for their ultralight sunscreens, while Neutrogena features a wide range of oil-free cleansers and acne-fighting treatments.
Neutrogena or ISDIN: which sunscreen is better?
Both brands offer top-tier sunscreens, but ISDIN fits dry sensitive skin at a Superior level while Neutrogena reaches an Average level. Neutrogena sunscreens like Ultra Gentle Daily Cleanser and Ultra Sheer Dry-Touch Sunscreen work well for oily and combination types.
Neutrogena or ISDIN for sensitive skin?
Both brands offer solid options for sensitive skin, but Lovi rates ISDIN as having a Superior routine fit compared to Neutrogena's High fit. ISDIN provides skin-friendly sunscreens and lightweight moisturizers that help calm sensitive skin.
Neutrogena or ISDIN for acne-prone skin?
Both Neutrogena and ISDIN achieve a High routine fit for acne-prone skin, while Lovi rates ISDIN as Superior and Neutrogena as High for acne-prone skin overall. Neutrogena offers acne-safe and gentle moisturizers on this page.
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)
Evaluation of moisturizing and irritation potential of sacha inchi oil
Solid lipid nanoparticles bearing oxybenzone: in-vitro and in-vivo evaluation
Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Functional properties and skin care effects of sodium trehalose sulfate
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-

Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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