Neutrogena vs ISDIN
Neutrogena and ISDIN are well-regarded skincare brands that offer diverse daily solutions for complex skin needs. Neutrogena is an American brand known for nourishing moisturizers, protective sunscreens, gentle cleansers, and refreshing toners featuring glycerin, hyaluronic acid, and dimethicone, which suit sensitive and acne-prone skin best. Meanwhile, the Spanish brand ISDIN is celebrated for its elegant moisturizers, advanced sunscreens, restorative serums, and targeted eye products that suit dry and sensitive skin best. While both brands support healthy complexions, they differ in their specific formulations and heritage.
Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.
investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
puig.combeautymatter.comuploads.puig.com
This page compares some of the most popular Neutrogena and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Neutrogena vs ISDIN products
People Say
Lightweight and non-greasy texture Mostly MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “Absorbs instantly without sticky residue — Neutrogena Hydro Boost Water Gel”
Deep hydration and moisture Mostly MentionedMostly Mentioned
- “Skin looked plumper and radiant — Neutrogena HYDRO BOOST WATER CREAM”
- “It also hydrates my skin. This cream has been so easy to add to my routine. — Neutrogena Retinol Regenerating Cream”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
Sensitive skin friendly and gentle Mostly MentionedOften Mentioned
- “leaves skin soft and balanced — Neutrogena Ultra Gentle Daily Cleanser”
- “love that it has no scent — Neutrogena Ultra Gentle Daily Cleanser”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Makeup compatibility and base Sometimes NotedOften Mentioned
- “Foundation glides right over it — Neutrogena Hydro Boost Water Gel”
- “Concealer doesn't cake or get stuck in crevices — Neutrogena Hydro Boost Eye Gel-Cream”
- “acts like a primer — ISDIN Eryfotona Actinica”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Skin texture improvement and anti-aging Sometimes NotedRarely Noted
- “Skin is looking smoother — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “Deep lines have softened — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “I can see a difference in my forehead wrinkles. — Neutrogena Retinol Regenerating Cream”
- “skin was much smoother — ISDIN Retinal Intense Serum”
Cooling and soothing sensation Rarely NotedSometimes Noted
- “Feels amazing and cold on the skin — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
- “Feels refreshing and cool on application — Neutrogena Hydro Boost Water Gel”
- “applicator has a cooling effect — ISDIN K-Ox Eyes”
Price vs quantity and high cost Sometimes NotedOften Mentioned
- “Jar is too small for the price — Neutrogena Hydro Boost Water Gel”
- “Runs out quickly — Neutrogena HYDRO BOOST WATER CREAM”
- “Tube is tiny for the cost — Neutrogena Hydro Boost Eye Gel-Cream”
- “very expensive — ISDIN Eryfotona Actinica”
Strong fragrance and scent issues Sometimes NotedOften Mentioned
- “Smell is too overpowering and lingering — Neutrogena Hydro Boost Water Gel”
- “Scent is so off-putting — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “smell is overpowering — ISDIN Eryfotona Actinica”
- “lingering headache inducing effect — ISDIN K-Ox Eyes”
Packaging and design issues Sometimes NotedRarely Noted
- “Pump stopped working — ISDIN Hyaluronic Concentrate”
- “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
- “Eye holes are too small — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
Neutrogena vs ISDIN routines for dry skin
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Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
$19.99
-
Hydrating Toner
Pyunkang Yul Calming Deep Moisture Toner
Morning
$16.99
-
Moisturizer
SKIN1004 Madagascar Centella Probio-Cica Enrich Cream
Morning · Evening · Once a week
$22.00
-
SPF
Fusion Water
Morning
$38.00
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
$21.70
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
$115.00
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
$22.00
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
$26.99
-
Hydrating Toner
Alcohol-Free Toner
Morning
$6.34
-
Moisturizer
Hydro Boost Hyaluronic Acid Serum
Morning · Evening · Once a week
$18.49
-
SPF
Clear Face Liquid Lotion Sunscreen
Morning
$12.48
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
$34.83
-
Serum or Treatment
Stubborn Marks PM Treatment
Evening · Once a week
$19.35
-
Nourishing Mask
Hydro Boost Hydrating Hydrogel Mask
Once a week
$2.97
Buy ISDIN routine · $255.68 · 94% fit
Buy Neutrogena routine · $121.45 · 75% fitSee multi-brand routine · 99% fit
Neutrogena vs ISDIN routines for oily skin
-
Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
$15.97
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
$15.60
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
$18.99
-
SPF
Eryfotona Actinica
Morning
$46.00
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
$50.00
-
Cleansing Toner
Pixi Glow Tonic
Evening
$28.42
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
$115.00
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
$69.00
-
Cleansing Mask
Revision Skincare Black Mask
Once a week
$79.00
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
$26.99
-
Hydrating Toner
Alcohol-Free Toner
Morning · Once a week
$6.34
-
Moisturizer
Hydro Boost+ Niacinamide Serum
Morning · Evening · Once a week
$14.99
-
SPF
Clear Face Liquid Lotion Sunscreen
Morning
$12.48
-
Pre-Cleanser
Oil-Free Eye Makeup Remover
Evening · Once a week
$9.97
-
Cleansing Toner
Blackhead Eliminating Cleansing Toner
Evening
$25.36
-
Serum or Treatment
Stubborn Marks PM Treatment
Evening · Once a week
$19.35
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
$69.00
-
Cleansing Mask
Revision Skincare Black Mask
Once a week
$79.00
Buy ISDIN routine · $437.98 · 93% fit
Buy Neutrogena routine · $263.48 · 74% fitSee multi-brand routine · 98% fit
Neutrogena vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
$28.08
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
$25.60
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
$18.99
-
SPF
Eryfotona Actinica
Morning
$46.00
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
$50.00
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
$18.90
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
$115.00
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
$69.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
$58.00
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
$26.99
-
Hydrating Toner
Alcohol-Free Toner
Morning · Once a week
$6.34
-
Moisturizer
Hydro Boost Hyaluronic Acid Serum
Morning · Evening · Once a week
$18.49
-
SPF
Ultra Sheer Dry-Touch Sunscreen
Morning
$9.88
-
Pre-Cleanser
Oil-Free Eye Makeup Remover
Evening · Once a week
$9.97
-
Cleansing Toner
Blackhead Eliminating Cleansing Toner
Evening
$25.36
-
Serum or Treatment
Stubborn Marks PM Treatment
Evening · Once a week
$19.35
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
$69.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
$58.00
Buy ISDIN routine · $429.57 · 93% fit
Buy Neutrogena routine · $243.38 · 77% fitSee multi-brand routine · 97% fit
Questions and answers
Neutrogena or ISDIN: which is better?
ISDIN is better suited for most skin types, offering a Superior routine fit for dry, sensitive, oily, combination, acne-prone, mature, and dark-spot skin, whereas Neutrogena has a High or Average fit across those categories. Neutrogena is better for skin texture improvement and anti-aging, while ISDIN is noted for its ultralight sunscreens.
What is the difference between Neutrogena and ISDIN?
Neutrogena offers a larger range of products on this page and tends to be more affordable, while ISDIN achieves a Superior routine fit for dry, oily, combination, sensitive, acne-prone, and mature skin types. Both brands feature lightweight moisturizers and include options for sensitive skin, but Neutrogena does better for skin texture improvement and anti-aging.
Neutrogena or ISDIN for dry skin?
ISDIN is a better fit for dry skin, offering a Superior routine fit compared to Neutrogena's High fit on this page. Ingredients like hyaluronic acid and retinol help improve skin hydration and combat signs of aging.
Journal of Pharmacy & Pharmaceutical Sciences, 2015The Journal of Investigative Dermatology, 2000
Neutrogena or ISDIN: which moisturizer is better?
ISDIN offers a superior routine fit for dry skin compared to Neutrogena, which has an Average fit for its dry skin moisturizers on this page. Ingredients like hyaluronic acid found in these products help improve skin hydration and combat signs of aging.
Dermatologic Therapy, 2022Journal of Pharmacy & Pharmaceutical Sciences, 2015
Which is more affordable, Neutrogena or ISDIN?
Neutrogena is more affordable, whereas ISDIN is frequently noted by reviewers for its high price point. Neutrogena pricing concerns are more related to packaging and value.
Which brand has more fragrance-free products, Neutrogena or ISDIN?
Neutrogena has more fragrance-free products on this page, with 35 out of 39 listing no fragrance compared to ISDIN which has 3 out of 8.
Neutrogena or ISDIN for oily skin?
For oily skin, ISDIN is a Superior fit, whereas Neutrogena has an Average fit on this page. Reviewers note that ISDIN offers ultralight and skin-friendly sunscreens, while Neutrogena features products containing salicylic acid that may help manage excess oil.
Neutrogena or ISDIN: which sunscreen is better?
ISDIN is the better brand for sunscreens, as Lovi rates its routine fit for dry skin, sensitive skin, and other skin types as Superior, compared to Neutrogena which ranges from Average to High. ISDIN's sunscreens are well-known for their ultralight and makeup-friendly textures.
Neutrogena or ISDIN for sensitive skin?
Lovi rates ISDIN as Superior for sensitive skin, while Neutrogena is High. Both brands feature gentle, sensitive skin-friendly options.
Neutrogena or ISDIN for acne-prone skin?
Both brands are great choices for acne-prone skin, with Lovi rating Neutrogena High and ISDIN High for this skin type. Neutrogena offers a wide variety of products on this page tailored for breakouts, while ISDIN features lightweight options like Fusion Water sunscreen.
Neutrogena or ISDIN for mature skin?
ISDIN is a Superior fit for mature skin, whereas Neutrogena has a High fit level for this skin type on the products on this page. Topical retinol helps stimulate collagen accumulation and improves the signs of aging in human skin.
The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007
Neutrogena or ISDIN for skin with dark spots?
For skin with dark spots, ISDIN has a Superior Lovi fit level with Eryfotona Actinica, while Neutrogena products on this page generally reach a High fit level.
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)
Evaluation of moisturizing and irritation potential of sacha inchi oil
Solid lipid nanoparticles bearing oxybenzone: in-vitro and in-vivo evaluation
Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Functional properties and skin care effects of sodium trehalose sulfate
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-

Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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