Neutrogena vs ISDIN
Neutrogena and ISDIN are well-regarded skincare brands, with the former founded in America in 1930 and the latter established in Spain in 1975. Neutrogena is known for its moisturizers, sunscreens, cleansers, and toners relying on glycerin, hyaluronic acid, and dimethicone, whereas ISDIN is celebrated for its advanced sunscreens, targeted serums, and soothing eye products driven by expert formulas. The American brand suits dry and mature skin best, while the Spanish brand is ideal for sensitive and mature skin. They differ primarily in their regional origins, parent companies, and specific ingredient profiles, offering tailored solutions for diverse complexions.
Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.
investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
puig.combeautymatter.comuploads.puig.com
This page compares some of the most popular Neutrogena and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Neutrogena vs ISDIN products
People Say
Lightweight and non-greasy texture Mostly MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “Absorbs instantly without sticky residue — Neutrogena Hydro Boost Water Gel”
Deep hydration and moisture Mostly MentionedMostly Mentioned
- “Skin looked plumper and radiant — Neutrogena HYDRO BOOST WATER CREAM”
- “It also hydrates my skin. This cream has been so easy to add to my routine. — Neutrogena Retinol Regenerating Cream”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
Sensitive skin friendly and gentle Mostly MentionedOften Mentioned
- “leaves skin soft and balanced — Neutrogena Ultra Gentle Daily Cleanser”
- “love that it has no scent — Neutrogena Ultra Gentle Daily Cleanser”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Makeup compatibility and base Sometimes NotedOften Mentioned
- “Foundation glides right over it — Neutrogena Hydro Boost Water Gel”
- “Concealer doesn't cake or get stuck in crevices — Neutrogena Hydro Boost Eye Gel-Cream”
- “acts like a primer — ISDIN Eryfotona Actinica”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Skin texture improvement and anti-aging Sometimes NotedRarely Noted
- “Skin is looking smoother — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “Deep lines have softened — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “I can see a difference in my forehead wrinkles. — Neutrogena Retinol Regenerating Cream”
- “skin was much smoother — ISDIN Retinal Intense Serum”
Cooling and soothing sensation Rarely NotedSometimes Noted
- “Feels amazing and cold on the skin — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
- “Feels refreshing and cool on application — Neutrogena Hydro Boost Water Gel”
- “applicator has a cooling effect — ISDIN K-Ox Eyes”
Price vs quantity and high cost Sometimes NotedOften Mentioned
- “Jar is too small for the price — Neutrogena Hydro Boost Water Gel”
- “Runs out quickly — Neutrogena HYDRO BOOST WATER CREAM”
- “Tube is tiny for the cost — Neutrogena Hydro Boost Eye Gel-Cream”
- “very expensive — ISDIN Eryfotona Actinica”
Strong fragrance and scent issues Sometimes NotedOften Mentioned
- “Smell is too overpowering and lingering — Neutrogena Hydro Boost Water Gel”
- “Scent is so off-putting — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “smell is overpowering — ISDIN Eryfotona Actinica”
- “lingering headache inducing effect — ISDIN K-Ox Eyes”
Packaging and design issues Sometimes NotedRarely Noted
- “Pump stopped working — ISDIN Hyaluronic Concentrate”
- “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
- “Eye holes are too small — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
Neutrogena vs ISDIN routines for dry skin
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Cleanser
CeraVe Hydrating Facial Cleanser
Morning · Evening · Once a week
€8.85
-
Hydrating Toner
Paula's Choice Advanced Replenishing Toner
Morning
€34.00
-
Moisturizer
d'Alba First Spray Serum
Morning · Evening · Once a week
€16.99
-
SPF
Fusion Water
Morning
€25.99
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€10.97
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
-
Nourishing Mask
Abib Rice Probiotics Overnight Mask
Once a week
€15.30
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
€8.61
-
Hydrating Toner
Paula's Choice Advanced Replenishing Toner
Morning
€34.00
-
Moisturizer
Hydro Boost Hyaluronic Acid Serum
Morning · Evening · Once a week
€8.83
-
SPF
Ultra Sheer Dry-Touch Sunscreen
Morning
€12.95
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
€7.99
-
Serum or Treatment
SKIN1004 Madagascar Centella Poremizing Fresh Ampoule
Evening · Once a week
€14.98
-
Nourishing Mask
Abib Rice Probiotics Overnight Mask
Once a week
€15.30
Neutrogena vs ISDIN routines for oily skin
-
Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
€20.50
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
SKIN1004 Centella Cream
Morning · Evening · Once a week
€17.49
-
SPF
Eryfotona Actinica
Morning
€32.49
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€97.52
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
€16.90
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€16.79
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
€8.61
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Hydro Boost+ Niacinamide Serum
Morning · Evening · Once a week
€10.49
-
SPF
Ultra Sheer Dry-Touch Sunscreen
Morning
€12.95
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
€7.99
-
Cleansing Toner
Blackhead Eliminating Cleansing Toner
Evening
€3.95
-
Serum or Treatment
The Ordinary Niacinamide 10% + Zinc 1%
Evening · Once a week
€5.20
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Clear Pore Cleanser/Mask
Once a week
€3.95
Neutrogena vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
€39.80
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
SPF
Eryfotona Actinica
Morning
€32.49
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€97.52
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€16.98
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Origins Original Skin Retexturizing Mask with Rose Clay
Once a week
€28.50
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
€8.61
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Hydro Boost Hyaluronic Acid Serum
Morning · Evening · Once a week
€8.83
-
SPF
Ultra Sheer Dry-Touch Sunscreen
Morning
€12.95
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
€7.99
-
Cleansing Toner
Blackhead Eliminating Cleansing Toner
Evening
€3.95
-
Serum or Treatment
SKIN1004 Madagascar Centella Spot Cream
Evening · Once a week
€18.49
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Clear Pore Cleanser/Mask
Once a week
€3.95
Questions and answers
Neutrogena or ISDIN: which is better?
Both Neutrogena and ISDIN are great brands, but ISDIN has a Superior Lovi fit across all skin types on this page. Neutrogena offers more affordable options and better skin texture improvement, while ISDIN excels in ultralight, makeup-friendly sunscreens.
What is the difference between Neutrogena and ISDIN?
Neutrogena is an American brand founded in 1930, while ISDIN is a Spanish brand founded in 1975. Both brands offer products with good Lovi fit levels across multiple skin types, but ISDIN achieves a Superior routine fit for dry sensitive skin and oily acne-prone skin compared to Neutrogena's Average and High levels. Reviewers note that ISDIN excels in ultralight sunscreens, whereas Neutrogena is recognized for its anti-aging moisturizers.
Neutrogena or ISDIN for dry skin?
Both Neutrogena and ISDIN offer great options for dry skin, with Lovi fit levels of High and Superior respectively. The products on this page for Neutrogena include hydrating favorites like Hydro Boost Hyaluronic Acid Serum, while ISDIN features lightweight formulas like Fusion Water.
Journal of Pharmacy & Pharmaceutical Sciences, 2015Dermatologic Therapy, 2022
Neutrogena or ISDIN: which moisturizer is better?
Neutrogena is a better choice for most moisturizers, as the products on this page offer deep hydration and anti-aging benefits with ingredients like retinol and hyaluronic acid. ISDIN also provides lightweight moisturizers, but reviewers note a high price point for the brand.
The Journal of Investigative Dermatology, 2000Journal of Pharmacy & Pharmaceutical Sciences, 2015
Which is more affordable, Neutrogena or ISDIN?
Neutrogena is more affordable, whereas ISDIN is frequently noted by reviewers for its high price point.
Neutrogena or ISDIN: which brand is better for mature skin?
Both Neutrogena and ISDIN offer great options for mature skin, with Lovi rating Neutrogena High and ISDIN Superior for this skin type. Neutrogena features anti-aging moisturizers with ingredients like retinol that help stimulate collagen accumulation in naturally aged skin.
The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007
Neutrogena or ISDIN: which brand has more fragrance-free products?
Neutrogena has more fragrance-free products on this page, with 35 out of 39 products listing no fragrance, compared to 3 out of 8 for ISDIN.
Neutrogena or ISDIN: which brand is better for reducing skin texture issues and signs of aging?
Neutrogena does better for skin texture improvement and anti-aging according to the review themes on this page. Ingredients like retinol help improve the appearance of aging skin.
Neutrogena or ISDIN for oily skin?
For oily skin, ISDIN has a Superior Lovi fit level, whereas Neutrogena has a High Lovi fit level on this page. Reviewers note that ISDIN offers ultralight sunscreens, while Neutrogena features products like Oil-Free Acne Wash.
Neutrogena or ISDIN: which sunscreen is better?
ISDIN sunscreens achieve a Superior Lovi fit level for dry sensitive skin on this page, while Neutrogena sunscreens reach an Average fit level for that skin type. Reviewers mostly mention that ISDIN sunscreens are ultralight.
Neutrogena or ISDIN for sensitive skin?
Both brands offer solid options for sensitive skin, with Lovi giving Neutrogena a High fit and ISDIN a Superior fit. Reviewers often mention that both product lines are gentle and skin-friendly, though ISDIN is particularly praised for its ultralight sunscreens.
Neutrogena or ISDIN for acne-prone skin?
Both Neutrogena and ISDIN offer great options for acne-prone skin, with ISDIN achieving a Superior routine fit and Neutrogena achieving a High routine fit on Lovi. Neutrogena features several products tailored for this skin type, such as the Ultra Gentle Daily Cleanser, which has a Superior fit.
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)
Evaluation of moisturizing and irritation potential of sacha inchi oil
Solid lipid nanoparticles bearing oxybenzone: in-vitro and in-vivo evaluation
Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Functional properties and skin care effects of sodium trehalose sulfate
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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