Neutrogena vs ISDIN
Neutrogena and ISDIN are established skincare brands from America and Spain, respectively. Neutrogena is celebrated for its reliable moisturizers, sunscreens, cleansers, and toners formulated with glycerin, hyaluronic acid, and dimethicone, while ISDIN is loved for its elegant moisturizers, advanced sunscreens, restorative serums, and targeted eye products. The American brand suits oily acne-prone skin and acne-prone skin best, whereas the Spanish offerings suit dry skin and sensitive skin best, providing gentle daily comfort and dependable protection. They differ mainly in their ingredient focus and regional heritage, offering distinct solutions like the Daily Facial Moisturizer and Fusion Water to address specific concerns.
Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.
investor.kimberly-clark.comen.wikipedia.orginvestors.kenvue.com
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
puig.combeautymatter.comuploads.puig.com
This page compares some of the most popular Neutrogena and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Neutrogena vs ISDIN products
People Say
Lightweight and non-greasy texture Mostly MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “Absorbs instantly without sticky residue — Neutrogena Hydro Boost Water Gel”
Deep hydration and moisture Mostly MentionedMostly Mentioned
- “Skin looked plumper and radiant — Neutrogena HYDRO BOOST WATER CREAM”
- “It also hydrates my skin. This cream has been so easy to add to my routine. — Neutrogena Retinol Regenerating Cream”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
Sensitive skin friendly and gentle Mostly MentionedOften Mentioned
- “leaves skin soft and balanced — Neutrogena Ultra Gentle Daily Cleanser”
- “love that it has no scent — Neutrogena Ultra Gentle Daily Cleanser”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Makeup compatibility and base Sometimes NotedOften Mentioned
- “Foundation glides right over it — Neutrogena Hydro Boost Water Gel”
- “Concealer doesn't cake or get stuck in crevices — Neutrogena Hydro Boost Eye Gel-Cream”
- “acts like a primer — ISDIN Eryfotona Actinica”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Skin texture improvement and anti-aging Sometimes NotedRarely Noted
- “Skin is looking smoother — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “Deep lines have softened — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “I can see a difference in my forehead wrinkles. — Neutrogena Retinol Regenerating Cream”
- “skin was much smoother — ISDIN Retinal Intense Serum”
Cooling and soothing sensation Rarely NotedSometimes Noted
- “Feels amazing and cold on the skin — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
- “Feels refreshing and cool on application — Neutrogena Hydro Boost Water Gel”
- “applicator has a cooling effect — ISDIN K-Ox Eyes”
Price vs quantity and high cost Sometimes NotedOften Mentioned
- “Jar is too small for the price — Neutrogena Hydro Boost Water Gel”
- “Runs out quickly — Neutrogena HYDRO BOOST WATER CREAM”
- “Tube is tiny for the cost — Neutrogena Hydro Boost Eye Gel-Cream”
- “very expensive — ISDIN Eryfotona Actinica”
Strong fragrance and scent issues Sometimes NotedOften Mentioned
- “Smell is too overpowering and lingering — Neutrogena Hydro Boost Water Gel”
- “Scent is so off-putting — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- “smell is overpowering — ISDIN Eryfotona Actinica”
- “lingering headache inducing effect — ISDIN K-Ox Eyes”
Packaging and design issues Sometimes NotedRarely Noted
- “Pump stopped working — ISDIN Hyaluronic Concentrate”
- “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
- “Eye holes are too small — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
Neutrogena vs ISDIN routines for dry skin
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Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
€21.95
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Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
€16.89
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Moisturizer
Elizabeth Arden Advanced Ceramide Lift and Firm Night Cream
Morning · Evening · Once a week
€48.84
-
SPF
Fusion Water
Morning
€24.98
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€11.83
-
Cleansing Toner
ROUND LAB 1025 Dokdo Cleansing Water
Evening · Once a week
€13.99
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€45.97
-
Nourishing Mask
LANEIGE Water Sleeping Mask_EX
Once a week
€33.90
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
€8.40
-
Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
€16.89
-
Moisturizer
Hydro Boost Hyaluronic Acid Serum
Morning · Evening · Once a week
€11.99
-
SPF
Clear Face Liquid Lotion Sunscreen
Morning
€26.99
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
€9.99
-
Cleansing Toner
Blackhead Eliminating Cleansing Toner
Evening · Once a week
€17.48
-
Serum or Treatment
Peach & Lily Glass Skin Refining Serum
Evening · Once a week
€86.59
-
Nourishing Mask
Hydro Boost Hydrating Hydrogel Mask
Once a week
€22.89
Neutrogena vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
€21.00
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€19.90
-
Moisturizer
SKIN1004 Centella Cream
Morning · Evening · Once a week
€19.20
-
SPF
Eryfotona Actinica
Morning
€32.43
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€11.83
-
Cleansing Toner
Pixi Glow Tonic
Evening
€18.05
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€45.97
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€72.82
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€15.72
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
€8.40
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€19.90
-
Moisturizer
Hydro Boost+ Niacinamide Serum
Morning · Evening · Once a week
€16.49
-
SPF
Clear Face Liquid Lotion Sunscreen
Morning
€26.99
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
€9.99
-
Cleansing Toner
Blackhead Eliminating Cleansing Toner
Evening
€17.48
-
Serum or Treatment
The Ordinary Niacinamide 10% + Zinc 1%
Evening · Once a week
€5.75
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€72.82
-
Cleansing Mask
Clear Pore Cleanser/Mask
Once a week
€9.99
Neutrogena vs ISDIN routines for combination skin
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Cleanser
Dr. Althea Amino Acid Gentle Bubble Cleanser
Morning · Evening · Once a week
€16.50
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
SKIN1004 Centella Cream
Morning · Evening · Once a week
€19.20
-
SPF
Eryfotona Actinica
Morning
€32.43
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€11.83
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening · Once a week
€16.99
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€45.97
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€15.72
-
Cleanser
Hydro Boost Water Gel
Morning · Evening · Once a week
€8.40
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Hydro Boost Hyaluronic Acid Serum
Morning · Evening · Once a week
€11.99
-
SPF
Ultra Sheer Dry-Touch Sunscreen
Morning
€17.70
-
Pre-Cleanser
HYDRO BOOST WATER CREAM
Evening · Once a week
€9.99
-
Cleansing Toner
Blackhead Eliminating Cleansing Toner
Evening · Once a week
€17.48
-
Serum or Treatment
Peach & Lily Glass Skin Refining Serum
Evening · Once a week
€86.59
-
Cleansing Mask
Clear Pore Cleanser/Mask
Once a week
€9.99
Questions and answers
Neutrogena or ISDIN: which is better?
Both brands are great, but ISDIN has a Superior routine fit for dry sensitive skin while Neutrogena has an Average fit. Neutrogena offers more anti-aging benefits, whereas ISDIN is often noted for ultralight sunscreens.
What is the difference between Neutrogena and ISDIN?
Neutrogena offers a wider range of products that may help improve skin texture and reduce signs of aging, while ISDIN is known for ultralight sunscreens and a superior fit for dry sensitive skin. Both brands generally feature lightweight and non-greasy options, though ISDIN comes with a higher price point.
The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007
Neutrogena or ISDIN for dry skin?
ISDIN is a better fit for dry skin, as Lovi rates its routine as Superior compared to Neutrogena's High fit. Reviewers also mention ISDIN for its lightweight moisturizers and ultralight sunscreens, while the products on this page help deliver deep hydration with key ingredients like hyaluronic acid.
Journal of Pharmacy & Pharmaceutical Sciences, 2015Dermatologic Therapy, 2022
Neutrogena or ISDIN: which moisturizer is better?
ISDIN is the better brand for moisturizers because Lovi rates its overall routine fit for dry skin as Superior while Neutrogena is High. ISDIN also wins for having a lighter and less greasy texture in the products on this page. Topical hyaluronic acid helps improve skin quality and signs of aging.
Which is more affordable, Neutrogena or ISDIN?
Neutrogena is more affordable, as reviewers frequently note high price points and a high price point for ISDIN, while Neutrogena faces price versus quantity and high cost issues less often.
Neutrogena or ISDIN: which has better lightweight and non-greasy texture according to reviewers?
ISDIN does better for lightweight and non-greasy texture according to reviewers.
How do the founding years and home countries of Neutrogena and ISDIN compare?
Neutrogena was founded in 1930 in the United States, whereas ISDIN was founded in 1975 in Spain.
Neutrogena or ISDIN: which brand is better for skin texture improvement and anti-aging?
Neutrogena does better for skin texture improvement and anti-aging according to reviewer themes on this page. Retinol helps reduce signs of aging in skin.
Neutrogena or ISDIN for oily skin?
Both Neutrogena and ISDIN offer products on this page that are a High fit for oily skin, but Lovi rates ISDIN as a Superior fit overall for this skin type.
Neutrogena or ISDIN: which sunscreen is better?
ISDIN sunscreen is a better fit for dry sensitive skin, with a Superior Lovi fit level compared to Neutrogena's Average fit. Both brands offer products with High or Superior fit levels for other skin types.
Neutrogena or ISDIN for sensitive skin?
Both brands offer products that fit sensitive skin well, with Lovi giving Neutrogena a High fit and ISDIN a Superior fit for sensitive skin routines. Reviewers note that both brands are sensitive skin friendly and gentle.
Neutrogena or ISDIN for acne-prone skin?
Both Neutrogena and ISDIN offer products on this page that are a High fit for acne-prone skin, with ISDIN achieving a Superior routine fit overall. Reviewers note that retinol helps improve skin texture and reduce signs of aging.
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)
Evaluation of moisturizing and irritation potential of sacha inchi oil
Solid lipid nanoparticles bearing oxybenzone: in-vitro and in-vivo evaluation
Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Functional properties and skin care effects of sodium trehalose sulfate
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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