Anua Green Lemon Vita C Blemish Serum for acne-prone skin

How to apply

Questions and answers

What the research says

• Topical combination of 5% sodium ascorbyl phosphate and 0.2% retinol reduced inflammatory acne lesions by 29.28% at 4 weeks and 63.10% at 8 weeks, outperforming either agent alone.

  International Journal of Cosmetic Science, 2009

• Combined ascorbyl palmitate and sodium ascorbyl phosphate treatment significantly reduced facial sebum secretions in healthy female volunteers compared to a placebo control over 90 days.

  Drug Research, 2017

• Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.

  The British Journal of Dermatology, 2002

• Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

  Experimental Dermatology, 2003

• Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

  Journal of Periodontology, 2009

• Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

  Journal of Cosmetic Dermatology, 2022

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls.

  Journal of the European Academy of Dermatology and Venereology, 2024

• Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2014

• Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity.

  The Journal of Clinical and Aesthetic Dermatology, 2025

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

Ingredients

Propanediol, Butylene Glycol, Dipropylene Glycol, Cyclopentasiloxane, 1,2-Hexanediol, Cyclohexasiloxane, Sodium Hydroxide, C12-14 Alketh-12, Alpha-Bisabolol, Sodium Polyacryloyldimethyl Taurate, Water, Polyacrylate Crosspolymer-6, Dimethicone Vinyl Dimethicone Crosspolymer, Xanthan Gum, Ethylhexylglycerin, Allantoin, Glycerin, Glutathione, Citrus Aurantium Dulcis Oil Flower, Litsea Cubeba Oil Fruit, Adenosine, Grapefruit Peel Oil, Disodium Edta, Bergamot Oil Fruit, Spearmint Oil Leaf, Tocopherol, Ferulic Acid, Barosma Betulina Leaf Extract, N-Butyl Alcohol, Hydrogenated Lecithin, Polyglyceryl-10 Stearate, Sorbitol, Panthenol, Beta-Glucan, Sodium Hyaluronate, Sodium Ascorbyl Phosphate, Caprylic Capric Triglyceride, Helianthus Annuus Seed Oil Sunflower Seed Oil, Sucrose Stearate, Glyceryl Stearates, Beta-Carotene, Sodium Hyaluronate Crosspolymer, Niacinamide, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Thioctic Acid, Lycopodium Clavatum Extract, Equisetum Arvense Extract, Sodium Acetylated Hyaluronate, Pyridoxine, Hydroxypropyltrimonium Hyaluronate, Folic Acid, Biotin, Ceramide Np, Ubiquinone, Cyanocobalamin, Thiamine Hcl, Riboflavin, Linoleic Acid, Hesperidin, Ergothioneine, Limonene, Linalool, Citral

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.