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SK-II vs Sesderma

SK-II and Sesderma are distinguished skincare brands that offer targeted solutions for varying complexions. The Japanese brand is known for luxurious moisturizers, potent serums, clarifying toners, and restorative masks anchored by pitera, while the Spanish brand is beloved for advanced serums and meticulously engineered formulas featuring botanical extracts and active compounds. Both brands suit dry, acne-prone, sensitive, hyperpigmented, and aging skin types, though they differ through distinct formulations designed to address imbalances, refine texture, and promote a radiant complexion.

SK-II is a Japanese skincare brand founded in 1980 and owned by The Procter & Gamble Company since 1991.

en.wikipedia.orgdiscoversk-ii.wixsite.comglossy.co

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular SK-II and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Questions and answers

SK-II or Sesderma: which is better?

SK-II has a much wider range of products on this page with High Lovi fit levels across most skin types, whereas Sesderma only features one serum. SK-II products on this page list no fragrance, while Sesderma includes fragrance in its serum.

What is the difference between SK-II and Sesderma?

SK-II offers a larger variety of fragrance-free products on this page and achieves High or Superior Lovi fit levels for several skin types, while Sesderma features only one serum on this page, which contains fragrance. Pitera is the key ingredient across the products on the SK-II page.

Which is more affordable, SK-II or Sesderma?

This page does not compare prices for SK-II or Sesderma products, so it is unclear which brand is more affordable.

Which causes fewer breakouts, SK-II or Sesderma?

SK-II has a high fit for acne-prone skin with the products on this page, whereas Sesderma also offers a high fit for acne-prone skin with its serum. Lovi gives SK-II an acne-prone fit level ranging from Average to Superior depending on the product, while Sesderma's Azelac RU Serum reaches a High fit for acne-prone skin.

Pharmaceutics, 2021

How do the founding years and countries of origin compare between SK-II and Sesderma?

SK-II was founded in 1980 in Japan, while Sesderma was founded in 1989 in Spain.

Which brand offers products entirely free of fragrance according to their ingredients lists?

SK-II offers products on this page that list no fragrance in their ingredients, whereas Sesderma includes fragrance in its serum.

How does the Lovi fit level of the Genoptics Ultraura Essence compare to the Azelac RU Serum for acne-prone skin?

For acne-prone skin, the Genoptics Ultraura Essence by SK-II achieves a Superior Lovi fit level, whereas the Azelac RU Serum by Sesderma reaches a High fit level.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.