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Kiehl's vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Kiehl's and Sesderma are respected skincare brands offering thoughtful moisturizers, advanced serums, toners, eye products, and meticulously engineered formulas. The American line incorporates nourishing glycerin and squalane to suit combination and mature skin, while the Spanish brand's active compounds suit sensitive and hyperpigmented skin. Both brands address acne-prone skin through targeted products like the Calendula Herbal-Extract Toner and the Azelac RU Serum. They differ primarily in their founding heritage and specific active ingredients, yet each provides dedicated care.

Kiehl's is an American skincare brand founded in 1851 and owned by L'Oréal S.A. since 2000.

loreal.comen.wikipedia.org

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Kiehl's and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Kiehl's vs Sesderma products

Kiehl's vs Sesderma serums and treatments

Questions and answers

Kiehl's or Sesderma: which is better?

Kiehl's offers a much wider variety of products on this page across multiple skin types compared to Sesderma, which only lists a single serum. Kiehl's lightweight, non-greasy moisturizers and gentle serums frequently help with hydration and skin texture, though some reviewers note potential breakouts and irritation.

What is the difference between Kiehl's and Sesderma?

Kiehl's offers a broad selection of twenty-eight products on this page spanning cleansers, toners, serums, and moisturizers with a high fit for skin with dark spots and combination skin, whereas Sesderma features only one product on this page, the Azelac RU Serum. Kiehl's is mostly fragrance-free with twenty-six out of twenty-eight products containing no fragrance, while Sesderma's single product includes fragrance.

Which is more affordable, Kiehl's or Sesderma?

Reviewers often note a high price point for Kiehl's, while pricing for Sesderma is not discussed on this page.

Which causes fewer breakouts, Kiehl's or Sesderma?

Reviewers often note that Kiehl's products may cause breakouts and skin irritation, while the products on this page for Sesderma have too few user reviews to compare on this point.

How do the founding years and countries of origin compare between Kiehl's and Sesderma?

Kiehl's was founded in 1851 in the United States, whereas Sesderma was founded later in 1989 in Spain.

Which of the two brands offers a larger selection of products on this page?

Kiehl's offers a much larger selection of products on this page than Sesderma. The products on this page for Kiehl's include dozens of options across multiple categories, whereas Sesderma is represented by only a single product.

Do products from both Kiehl's and Sesderma contain fragrance, or is it exclusive to one brand?

Fragrance is not exclusive to one brand, as products from both Kiehl's and Sesderma contain fragrance. On the Kiehl's page, two products include fragrance while most do not, whereas the single Sesderma product listed also contains fragrance.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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