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Kiehl's vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Kiehl's and Sesderma are trusted skincare brands that offer distinct approaches to daily care. The American house, founded in 1851, is known for nourishing moisturizers, targeted serums, soothing toners, and revitalizing eye products utilizing glycerin and squalane to suit mature and combination skin. Meanwhile, the Spanish creator, established in 1989, is beloved for advanced serums and meticulous formulas tailored for sensitive, hyperpigmented, and aging skin types. While both brands address specific concerns like acne-prone skin through specialized offerings, Kiehl's relies on moisture-retention properties, whereas its counterpart employs botanical extracts and active compounds for radiance.

Kiehl's is an American skincare brand founded in 1851 and owned by L'Oréal S.A. since 2000.

loreal.comen.wikipedia.org

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Kiehl's and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Kiehl's vs Sesderma products

Kiehl's vs Sesderma serums and treatments

Questions and answers

Kiehl's or Sesderma: which is better?

Kiehl's offers a much wider variety of skincare options on this page than Sesderma, which only lists a single product. Reviewers note that Kiehl's provides lightweight moisturizers and gentle serums, though some users report high prices and breakouts.

What is the difference between Kiehl's and Sesderma?

Kiehl's offers a wide range of products on this page spanning cleansers, toners, serums, and moisturizers that fit mature skin and combination skin at a High level, whereas Sesderma is represented by a single serum.

Which is more affordable, Kiehl's or Sesderma?

The products on this page for Kiehl's often have a high price point, but affordability cannot be compared since Sesderma has only one product listed here and no pricing details are provided.

Which causes fewer breakouts, Kiehl's or Sesderma?

Kiehl's features products on this page with a High Lovi fit for acne-prone skin, such as the Ultra Facial Oil-Free Gel Cream, whereas Sesderma offers only the Azelac RU Serum, which has a High Lovi fit for acne-prone skin.

How do the founding years and countries of origin compare between Kiehl's and Sesderma?

Kiehl's was founded in 1851 in the United States, whereas Sesderma was founded in 1989 in Spain.

Which products from Kiehl's and Sesderma contain fragrance according to the page?

According to the page, the Kiehl's products that contain fragrance are the Age Defender Moisturizer and the Facial Fuel Energizing Moisture Treatment for Men, while for Sesderma it is the Azelac RU Serum.

What are some of the key ingredients found across Kiehl's products?

Glycerin, Vitamin C, Squalane, Shea butter, and Vitamin E are key ingredients found across the products on this page for Kiehl's.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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