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Kiehl's vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Kiehl's and Sesderma are well-established skincare brands that cater to varying complexion needs through distinct formulations. Kiehl's is known for its nourishing moisturizers, targeted serums, soothing toners, and gentle eye products featuring glycerin and squalane, while Sesderma is beloved for its advanced serums and meticulously engineered formulas. The American brand suits mature skin and sensitive skin best, whereas the Spanish brand is ideal for sensitive, hyperpigmented, and aging skin types. Both brands differ in their geographical origins, founding years, and specific active ingredients, offering tailored approaches for those seeking targeted skincare solutions.

Kiehl's is an American skincare brand founded in 1851 and owned by L'Oréal S.A. since 2000.

loreal.comen.wikipedia.org

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Kiehl's and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Kiehl's vs Sesderma products

Kiehl's vs Sesderma serums and treatments

Questions and answers

Kiehl's or Sesderma: which is better?

Kiehl's offers a much broader range of products on this page than Sesderma, with High or Superior Lovi fit levels across multiple skin types like sensitive skin and skin with dark spots. Reviewers often mention its lightweight moisturizers and deep hydration, though some note a high price point and irritation.

What is the difference between Kiehl's and Sesderma?

Kiehl's features a large variety of skincare products on this page that fit sensitive skin and mature skin with High to Superior levels, while Sesderma is represented by only one serum.

Which is more affordable, Kiehl's or Sesderma?

The products on this page do not list prices, so a direct comparison of affordability between Kiehl's and Sesderma cannot be made from this data.

Which causes fewer breakouts, Kiehl's or Sesderma?

Comparing the products on this page, Kiehl's includes options with high and average fit levels for acne-prone skin, while Sesderma is represented by Azelac RU Serum which has a high fit for acne-prone skin. Reviewers sometimes note that Kiehl's products may cause breakouts and skin irritation.

How does the country of origin and founding year compare between Kiehl's and Sesderma?

Kiehl's was founded in 1851 in the United States, while Sesderma was founded in 1989 in Spain.

Which brand offers more fragrance-free skincare options among the products listed?

Kiehl's offers significantly more fragrance-free skincare options, as 26 of the 28 products on this page list no fragrance. In contrast, the only listed Sesderma product contains fragrance.

What are the key shared ingredients found across the products of these two brands?

Comparing the products on this page, a direct overlap in key ingredients is not highlighted between Kiehl's and Sesderma. Kiehl's features key ingredients such as glycerin, vitamin C, squalane, shea butter, and vitamin E.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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