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Kiehl's vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Kiehl's and Sesderma are well-established skincare brands offering specialized formulas for diverse skin types and concerns. Kiehl's is an American brand that provides expertly formulated moisturizers, serums, toners, and eye products with nourishing glycerin and squalane, suiting combination and mature skin best. Meanwhile, Sesderma is a Spanish brand known for advanced serums and meticulously engineered formulas, catering ideally to sensitive, hyperpigmented, and aging skin. While both companies deliver targeted solutions, they differ in their foundational ingredients, regional origins, and the specific complexions they primarily serve.

Kiehl's is an American skincare brand founded in 1851 and owned by L'Oréal S.A. since 2000.

loreal.comen.wikipedia.org

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Kiehl's and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Kiehl's vs Sesderma products

Kiehl's vs Sesderma serums and treatments

Questions and answers

Kiehl's or Sesderma: which is better?

Kiehl's offers a much wider variety of products across multiple skincare categories than Sesderma on this page. Reviewers note that Kiehl's provides lightweight moisturizers and gentle serums, though some mention a high price point and potential irritation.

What is the difference between Kiehl's and Sesderma?

Kiehl's offers a wide range of products on this page that generally fit combination skin, mature skin, and skin with dark spots, while Sesderma is represented by a single serum. Reviewers note that Kiehl's features lightweight, non-greasy moisturizers and gentle serums, though some mention a high price point and skin irritation.

Which is more affordable, Kiehl's or Sesderma?

Reviewers on this page often mention that Kiehl's has a high price point, but the page facts do not provide pricing information for Sesderma to make a direct comparison.

Which causes fewer breakouts, Kiehl's or Sesderma?

Comparing the products on this page, Kiehl's includes options with a High Lovi fit for acne-prone skin, such as the Ultra Facial Oil-Free Gel Cream, whereas Sesderma is represented by a single product, the Azelac RU Serum, which also holds a High Lovi fit for acne-prone skin.

Which brand has been around longer, Kiehl's or Sesderma?

Kiehl's has been around longer than Sesderma, as it was founded in 1851 in the United States while Sesderma was founded in 1989 in Spain.

How do the countries of origin and ownership compare between Kiehl's and Sesderma?

Kiehl's was founded in the United States in 1851 and has been owned by L'Oréal S.A. since 2000, whereas Sesderma was founded in Spain in 1989 and is owned by Grupo Sesderma.

Which brand offers more fragrance-free products on the comparison page?

Kiehl's offers significantly more fragrance-free options, with 26 of its 28 products on this page listing no fragrance, compared to Sesderma which includes fragrance in all of its products listed here.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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