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Kiehl's vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Kiehl's and Sesderma are trusted skincare brands that offer reliable daily care for distinct complexions. Kiehl's is known for dependable moisturizers, serums, toners, and eye products featuring glycerin and squalane, while Sesderma is beloved for advanced serums and meticulously engineered formulas. The American brand suits mature skin and skin with dark spots best, whereas the Spanish brand suits sensitive, hyperpigmented, and aging skin types best. They differ primarily in their formulation approaches and regional heritage, providing targeted solutions like the Calendula Herbal-Extract Toner and the Azelac RU Serum.

Kiehl's is an American skincare brand founded in 1851 and owned by L'Oréal S.A. since 2000.

loreal.comen.wikipedia.org

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Kiehl's and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Kiehl's vs Sesderma products

Kiehl's vs Sesderma serums and treatments

Questions and answers

Kiehl's or Sesderma: which is better?

Kiehl's offers a much wider variety of products on this page compared to Sesderma, fitting mature skin, skin with dark spots, and combination skin best. Reviewers often mention lightweight, non-greasy moisturizers and gentle serums across the products on this page, while also noting a high price point and possible breakouts or skin irritation.

What is the difference between Kiehl's and Sesderma?

Kiehl's offers a wide range of skincare products on this page with High to Superior Lovi fit levels across most skin types, whereas Sesderma features only a single serum. Reviewers frequently note that Kiehl's provides lightweight moisturizers and gentle serums, though some users mention a high price point and skin irritation.

Which is more affordable, Kiehl's or Sesderma?

The products on this page for Kiehl's are often noted by reviewers to have a high price point. There is no pricing information available on this page for Sesderma to make a comparison.

Which causes fewer breakouts, Kiehl's or Sesderma?

When comparing breakouts, shoppers should note that the products on this page for Kiehl's have a risk of causing breakouts and skin irritation according to reviewers, whereas the single Sesderma product listed, Azelac RU Serum, is rated High for acne-prone skin.

Between Kiehl's and Sesderma, which brand offers products with fragrance?

Both Kiehl's and Sesderma offer products with fragrance on this page. Kiehl's lists fragrance in 2 of its products, while Sesderma includes fragrance in its sole listed product.

How do the founding years and countries of origin compare between Kiehl's and Sesderma?

Kiehl's was founded in 1851 in the United States, whereas Sesderma was founded in 1989 in Spain.

Which brand has more product variety listed on the page for treating skin with dark spots?

Kiehl's has significantly more product variety listed on the page for treating skin with dark spots, featuring multiple options like serums, toners, and sunscreens with High or Average Lovi fit levels for that skin type. In comparison, Sesderma only lists a single product, Azelac RU Serum, for the same concern.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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