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Kiehl's vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Kiehl's and Sesderma are distinguished skincare brands rooted in long-standing dermatological traditions. The American heritage label offers nourishing moisturizers, serums, toners, and eye products anchored by glycerin and squalane, while the Spanish innovator is beloved for advanced serums and meticulously engineered formulas. Kiehl's suits skin with dark spots and mature skin best, whereas the latter caters effectively to sensitive, hyperpigmented, and aging skin types. Both brands differ through their unique ingredient synergies, with the former emphasizing barrier restoration and the latter focusing on botanical refinement for radiant complexions.

Kiehl's is an American skincare brand founded in 1851 and owned by L'Oréal S.A. since 2000.

loreal.comen.wikipedia.org

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Kiehl's and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Kiehl's vs Sesderma products

Kiehl's vs Sesderma serums and treatments

Questions and answers

Kiehl's or Sesderma: which is better?

Kiehl's offers a much wider variety of skincare options on this page compared to Sesderma, which only lists a single product. Reviewers note that Kiehl's provides lightweight, non-greasy moisturizers and gentle serums, though some users frequently mention high prices and breakouts.

What is the difference between Kiehl's and Sesderma?

Kiehl's offers a wide range of twenty-eight skincare products featuring key ingredients like glycerin and vitamin C, whereas Sesderma is represented by only one product on this page. Kiehl's products on this page show high fit levels for several skin types, including skin with dark spots, mature skin, and dry skin.

Which is more affordable, Kiehl's or Sesderma?

Comparing the pricing of Kiehl's and Sesderma on this page, reviewers frequently mention that Kiehl's products have a high price point. The page facts do not provide enough pricing details for Sesderma to make a full comparison.

Which causes fewer breakouts, Kiehl's or Sesderma?

Comparing the products on this page, Kiehl's may cause breakouts and skin irritation according to reviewers, while Sesderma has only one product listed so a general comparison is not possible.

How do the founding years and countries of origin compare between Kiehl's and Sesderma?

Kiehl's was founded in 1851 in the United States, whereas Sesderma was founded later in 1989 in Spain.

Which Kiehl's products contain fragrance compared to Sesderma's Azelac RU Serum?

Only two Kiehl's products on this page list fragrance, while Sesderma's Azelac RU Serum also includes fragrance. Kiehl's offers mostly fragrance-free choices across its range.

What are the key ingredients found across Kiehl's products?

Kiehl's products feature several key ingredients across the range, including Glycerin, Vitamin C, Squalane, Shea butter, and Vitamin E.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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