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Clinique vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Clinique and Sesderma are established skincare developers from America and Spain that offer targeted formulations for various complexions. The American brand is loved for its moisturizers, serums, makeup removers, and eye products utilizing hyaluronic acid, glycerin, and caffeine, while the Spanish brand is beloved for its advanced serums and meticulously engineered formulas featuring botanical extracts and active compounds. Both brands suit sensitive skin best, with the first additionally suiting dry skin and the second additionally suiting hyperpigmented and aging skin. They differ primarily in their founding years, geographic origins, and specific ingredient profiles addressing distinct dermatological concerns.

Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..

en.wikipedia.orgelcompanies.combusinesswire.comglossy.co

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Clinique and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Clinique vs Sesderma products

Questions and answers

Clinique or Sesderma: which is better?

Clinique is better for a wider variety of skin types because the products on this page list no fragrance and feature key ingredients like hyaluronic acid and glycerin. Sesderma features only one product on this page, the Azelac RU Serum, which contains fragrance.

What is the difference between Clinique and Sesderma?

Clinique features a large range of fragrance-free products on this page that Lovi rates with a High fit for dry and sensitive skin, while Sesderma is represented by just one serum that contains fragrance. Hyaluronic acid helps provide the hydrating benefits commonly noted by shoppers for Clinique.

Dermatologic Therapy, 2022

Which is more affordable, Clinique or Sesderma?

The products on this page for Clinique often receive reviews noting a high price point. The provided page facts do not contain pricing information for Sesderma to make a comparison.

Which causes fewer breakouts, Clinique or Sesderma?

Clinique is rated as having an Average fit for acne-prone skin for several products on this page, whereas Sesderma has a High fit for its single featured product. Reviewers sometimes note that Clinique products may cause breakouts.

Which brand has been established longer, Clinique or Sesderma?

Clinique has been established longer, having been founded in the United States in 1968, whereas Sesderma was founded in Spain in 1989.

Do all Clinique products lack fragrance in their ingredients compared to Sesderma?

Yes, every product on the Clinique page lists no fragrance in its ingredients, whereas the Sesderma product on the page contains fragrance.

How many products are listed for Sesderma compared to Clinique on this page?

Clinique features 19 products on this page, whereas Sesderma lists only 1 product.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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