Medicube vs ISDIN
Medicube and ISDIN are established skincare brands offering thoughtful moisturizers, serums, and targeted solutions. The Korean creator founded in 2016 relies on niacinamide, collagen, and hyaluronic acid within its toners, masks, and creams to suit oily acne-prone and oily skin, whereas the Spanish house founded in 1975 crafts sophisticated sunscreens and eye products best suited for acne-prone and combination skin. While both brands address mature skin and dark spots through distinct standouts, the former balances excess sebum with specific gels, masks, and eye creams, and the latter nurtures the complexion with reliable, gentle efficacy.
Medicube is a Korean skincare brand founded in 2016 and owned by APR Corp..
medicubereviews.co.ukglossy.co
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
puig.combeautymatter.comuploads.puig.com
This page compares some of the most popular Medicube and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Medicube vs ISDIN products
People Say
Hydration and Moisture Mostly MentionedMostly Mentioned
- “skin feels bouncier and hydrated — Medicube PDRN Pink Peptide Serum”
- “glass skin — Medicube PDRN Pink Collagen Gel Mask”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Lightweight and Non-Greasy Texture Not notedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
Skin Texture and Smoothing Often MentionedOften Mentioned
- “gives my skin a smooth, glass-like finish — Medicube Zero Pore Pad”
- “skin feels smoother — Medicube PDRN Pink Peptide Serum”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
- “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum”
Glow and Brightening Often MentionedSometimes Noted
- “gave me instant glass skin — Medicube Collagen Jelly Cream”
- “woke up with glowing skin — Medicube Collagen Night Wrapping Mask”
- “Dark spots go away faster — Medicube Deep Vita C Pad”
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
Acne and Pore Care Often MentionedNot noted
- “Pores drastically reduced — Medicube Zero Foam Cleanser”
- “Removes every trace of oil — Medicube Red Foam Cleanser”
- “noticed a real difference in pore visibility — Medicube Zero Pore Pad”
High Price Point Sometimes NotedOften Mentioned
- “tube is tiny for the price — Medicube Collagen Night Wrapping Mask”
- “price is steep — Medicube PDRN Pink Collagen Gel Mask”
- “price is a bit steep — Medicube Red Succinic Acid Peeling Pad”
- “very expensive — ISDIN Eryfotona Actinica”
Strong Fragrance and Scent Often MentionedOften Mentioned
- “slightly fishy smell — Medicube PDRN Pink Peptide Serum”
- “smells like old lady perfume — Medicube Collagen Jelly Cream”
- “smell is overpowering — ISDIN Eryfotona Actinica”
- “lingering headache inducing effect — ISDIN K-Ox Eyes”
Packaging and Application Issues Sometimes NotedSometimes Noted
- “Pump stopped working — ISDIN Hyaluronic Concentrate”
- “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
- “Pilled up on my skin — ISDIN Hyaluronic Moisture”
- “messy — Medicube PDRN Pink Collagen Gel Mask”
Medicube vs ISDIN routines for dry skin
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Cleanser
CeraVe Hydrating Facial Cleanser
Morning · Evening · Once a week
AED 32.95
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Moisturizer
SKIN1004 Madagascar Centella Probio-Cica Enrich Cream
Morning · Evening · Once a week
AED 34.80
-
SPF
Fusion Water
Morning
AED 91.99
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
AED 35.29
-
Cleansing Toner
ROUND LAB 1025 Dokdo Cleansing Water
Evening
AED 38.99
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Serum or Treatment
Retinal Intense Serum
Evening · Once a week
AED 392.99
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Enzyme Powder
VT Cica Mild Powder Wash
Once a week
AED 47.62
-
Nourishing Mask
Mediheal Watermide Essential Mask
Once a week
AED 65.00
-
Cleanser
Zero Foam Cleanser
Morning · Evening · Once a week
AED 38.99
-
Hydrating Toner
Triple Collagen Toner
Morning
AED 38.55
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
AED 92.33
-
SPF
Dr.G Green Mild Up Sun+
Morning
AED 81.00
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
AED 35.29
-
Cleansing Toner
Zero Pore Pad
Evening
AED 41.99
-
Serum or Treatment
One Day Exosome Shot 2000
Evening · Once a week
AED 35.00
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Enzyme Powder
VT Cica Mild Powder Wash
Once a week
AED 47.62
-
Nourishing Mask
Deep Peptide Radiance Mask
Once a week
AED 49.99
Buy ISDIN routine · AED 739.63 · 88% fit
Buy Medicube routine · AED 460.76 · 86% fitSee multi-brand routine · 96% fit
Medicube vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
AED 49.95
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
AED 49.99
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
AED 33.40
-
SPF
Fusion Water
Morning
AED 91.99
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
AED 179.45
-
Cleansing Toner
Pixi Glow Tonic
Evening
AED 120.00
-
Serum or Treatment
Retinal Intense Serum
Evening · Once a week
AED 392.99
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
AED 101.09
-
Cleansing Mask
Revision Skincare Black Mask
Once a week
AED 204.00
-
Cleanser
Red Foam Cleanser
Morning · Evening · Once a week
AED 50.50
-
Hydrating Toner
Triple Collagen Toner
Morning · Once a week
AED 38.55
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
AED 92.33
-
SPF
d'Alba UVessence Mild Waterfull Sun Cream SPF 50
Morning
AED 92.70
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
AED 179.45
-
Cleansing Toner
Zero Pore Pad
Evening
AED 41.99
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
AED 101.09
-
Cleansing Mask
Zero Pore Blackhead Mud Mask
Once a week
AED 49.00
Buy ISDIN routine · AED 1,222.86 · 91% fit
Buy Medicube routine · AED 645.61 · 87% fitSee multi-brand routine · 97% fit
Medicube vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
AED 84.53
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
AED 145.00
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
AED 33.40
-
SPF
Fusion Water
Morning
AED 91.99
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
AED 179.45
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
AED 53.12
-
Serum or Treatment
Retinal Intense Serum
Evening · Once a week
AED 392.99
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
AED 101.09
-
Cleansing Mask
KORA Organics Turmeric Brightening & Exfoliating Mask
Once a week
AED 122.93
-
Cleanser
Red Foam Cleanser
Morning · Evening · Once a week
AED 50.50
-
Hydrating Toner
Triple Collagen Toner
Morning · Once a week
AED 38.55
-
Moisturizer
AGE-R Booster Gel
Morning · Evening · Once a week
AED 92.33
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
AED 179.45
-
Cleansing Toner
Zero Pore Pad
Evening
AED 41.99
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
AED 101.09
-
Cleansing Mask
Zero Pore Blackhead Mud Mask
Once a week
AED 49.00
Buy ISDIN routine · AED 1,204.50 · 92% fit
Buy Medicube routine · AED 552.91 · 86% fitSee multi-brand routine · 96% fit
Questions and answers
Medicube or ISDIN: which is better?
Medicube is better for glow and brightening, as well as acne and pore care, while ISDIN is better for a lightweight, non-greasy texture. Lovi rates ISDIN as Superior for oily skin, combination skin, sensitive skin, acne-prone skin, mature skin, skin with dark spots, and oily acne-prone skin, whereas Medicube has a High fit across all those same skin types.
What is the difference between Medicube and ISDIN?
Medicube offers more fragrance-free options and is praised for glow and pore care, while ISDIN stands out for its ultralight sunscreens and lighter textures. Both brands perform equally well for dry skin routines, but ISDIN holds a superior fit level for oily, sensitive, and acne-prone skin types.
Medicube or ISDIN for dry skin?
Both Medicube and ISDIN have a High routine fit for dry skin. The products on this page provide hydration and moisture, though reviewers note that Medicube may sometimes leave a sticky residue.
Medicube or ISDIN: which moisturizer is better?
When comparing moisturizers, ISDIN is lighter in texture, while Medicube delivers deeply hydrating formulas with key ingredients like hyaluronic acid and collagen that help improve skin quality and signs of aging.
Dermatologic Therapy, 2022Dermatology Practical & Conceptual, 2022
Which is more affordable, Medicube or ISDIN?
Medicube is more affordable, as high price points are noted as a drawback for ISDIN while pricing issues specifically regarding small quantities are mentioned for Medicube.
Medicube or ISDIN for oily skin?
For oily skin, ISDIN is a superior fit overall compared to Medicube. Both brands offer solid options like sunscreens and cleansers, but ISDIN provides a lightweight texture that works exceptionally well for this skin type.
Medicube or ISDIN for sensitive skin?
Both Medicube and ISDIN are suitable choices, as Lovi rates both brands as having a High fit for sensitive skin. Medicube features a high concentration of fragrance-free products on this page to help reduce irritation, while ISDIN offers ultralight sunscreens that are generally well-tolerated.
Medicube or ISDIN for acne-prone skin?
Medicube is a solid choice for acne-prone skin, as Lovi rates its routine fit as High. ISDIN also fits this skin type with a Superior Lovi rating. Both brands feature effective ingredients like niacinamide, which may help control skin aging and pigmentation.
Medicube or ISDIN for mature skin?
Both brands offer products for mature skin, but Lovi rates ISDIN as Superior overall and Medicube as High. Medicube provides good glow and brightening with ingredients like niacinamide, which helps reduce pigmentation. ISDIN features retinol options that help stimulate collagen accumulation in naturally aged skin.
The British Journal of Dermatology, 2002The Journal of Investigative Dermatology, 2000
Medicube or ISDIN for skin with dark spots?
Both brands are suitable, but ISDIN holds a Superior Lovi fit level for skin with dark spots, whereas Medicube reaches a High level. ISDIN features highly rated options like Eryfotona Actinica, and Medicube includes ingredients like niacinamide which may help reduce cutaneous pigmentation.
Medicube or ISDIN for dry sensitive skin?
Both Medicube and ISDIN are a High fit for dry sensitive skin on Lovi. Medicube offers high hydration moisturizers like the Collagen Jelly Cream, while ISDIN features ultralight sunscreens and soothing lotions.
Research behind their key ingredients
Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Effect of Camellia japonica oil on human type I procollagen production and skin barrier function
Protective effects of Camellia japonica flower extract against urban air pollutants
Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Functional properties and skin care effects of sodium trehalose sulfate
Composition characterization and clinical efficacy study of a salmon egg extract
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from Paeonia lactiflora
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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