NIVEA LUMINOUS630 ANTI-DARK SPOT SERUM for mature skin

How to apply

Questions and answers

What the research says

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• Optimized transfersomes loaded with epigallocatechin-3-gallate and hyaluronic acid increased cell viability while reducing lipid peroxidation, intracellular ROS, and MMP expression in HaCaT cells, and exhibited higher skin permeation and deposition compared to plain EGCG.

  Drug Delivery, 2017

• Vitamin E in O/W and W/O emulsions significantly increased stratum corneum hydration and enhanced water-binding capacity, with an optimum concentration of 5%.

  Arzneimittel-Forschung, 1998

• Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.

  Contemporary Clinical Trials Communications, 2021

• Treatment with the tyrosinase inhibitor Thiamidol significantly lightened suction blister-induced post-inflammatory hyperpigmentation and improved acne-related post-inflammatory hyperpigmentation compared to vehicle control over 3 months.

  International Journal of Cosmetic Science, 2021

• Four-times daily Thiamidol application improves facial hyperpigmentation significantly more than two-times daily application in subjects with mild-to-moderate facial hyperpigmentation, and a real-world three-product Thiamidol regimen shows significant improvement of hyperpigmentation and skin parameters.

  International Journal of Cosmetic Science, 2020

• Application of isobutylamido thiazolyl resorcinol twice daily prior to Q-switched Nd:YAG laser treatment significantly reduced the incidence of post-inflammatory hyperpigmentation at 4 weeks compared to no application in subjects with solar lentigines.

  Journal of Cosmetic Dermatology, 2024

• Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

  Experimental Dermatology, 2003

• Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

  Journal of Periodontology, 2009

• Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

  Journal of Cosmetic Dermatology, 2022

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.

  Journal of Cosmetic Dermatology, 2025

• Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.

  Journal of Cosmetic Dermatology, 2024

• A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use.

  Journal of Cosmetic Dermatology, 2022

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

Why other serums fit mature skin better

• Caviar oil enhanced adipocyte differentiation in vitro, reduced MMP expression while increasing collagen and elastin formation ex vivo, and improved skin moisture, elasticity, and density in 102 participants over four weeks of Cavi Balm usage compared to baseline.

  In Vivo, 2023

• Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.

  Journal of Cosmetic Dermatology, 2026

• A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.

  Journal of Cosmetic Dermatology, 2020

Ingredients

Water, Isopropyl Palmitate, Cetearyl Isononanoate, Dimethicone, Glycerin, Alcohol Denat, Cocoglycerides, Distarch Phosphate, Butylene Glycol, Methylpropanediol, Tapioca Starch, Isobutylamido Thiazolyl Resorcinol, Hyaluronic Acid, Tocopheryl Acetate, Stearyl Alcohol, Cetyl Alcohol, Glyceryl Stearate, Sodium Ascorbyl Phosphate, Sodium Stearoyl Glutamate, Sodium Polyacrylate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Trisodium Edta, Sodium Chloride, Sodium Hydroxide, Sodium Sulfate, Phenoxyethanol, Benzyl Alcohol, Parfum, Ci 15985, Ci 47005

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.