ISDIN Hyaluronic Concentrate for dry skin
Sodium Hyaluronate
Glycerin
Dimethicone
Palmitoyl Tripeptide-1
Pseudoalteromonas Extract Ferment
Average
- AverageDry Skin Fit
- AverageEffectiveness
- HighSafety
Works for dry skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate suitability for your dry skin due to the humectant action of glycerin and hydrolyzed hyaluronic acid, which provide hydration but lack sufficient emollient and occlusive ingredients for optimal moisture.
- The product provides excellent moisturizing benefits with hydrolyzed hyaluronic acid and sodium hyaluronate, offering deep hydration that supports general skincare needs.
- The safety profile is excellent, with no risks of irritation for your dry skin due to the absence of prohibited or harsh ingredients.
How to apply
- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
People Say
★4.7Overall rating based on 200+ reviewsUsers consistently praise this water-gel serum for its lightweight, fast-absorbing texture that delivers immediate hydration and a satin-smooth finish without leaving a greasy residue. It is frequently recommended for dry or dull skin types looking to plump early fine lines and improve overall radiance, though some users find it insufficient for very dry winter conditions or deep wrinkles.
Highlights
Lightweight texture Mostly Mentioned
- “Lightweight formula absorbs fast”
- “Goes on like silk”
- “Non-greasy satin finish”
Hydration and plumping Often Mentioned
- “Skin feels intensely hydrated”
- “Plumps up fine lines”
- “Great moisture boost”
Good skin tolerance Sometimes Noted
- “Didn't cause breakouts”
- “Good for acne-prone skin”
- “Soothing on sensitive skin”
Makeup compatibility Sometimes Noted
- “Great under makeup”
- “Kept makeup intact”
- “Perfect smooth base”
Pleasant scent Sometimes Noted
- “Smells absolutely amazing”
- “Light pleasant scent”
- “Soothing aloe fragrance”
High price Sometimes Noted
- “Hefty price tag”
- “Expensive for daily use”
- “Pricey but worth it”
Packaging issues Sometimes Noted
- “Pump stopped working”
- “Hard to get last drops”
- “Packaging makes it difficult”
Fragrance sensitivity Rarely Noted
- “Contains added fragrance”
- “Scent might bother sensitive”
- “Prefer fragrance-free skincare”
Winter efficacy Rarely Noted
- “Not hydrating enough in winter”
- “Need thicker cream over it”
- “Better for summer months”
Sources: lovi.care, isdin.com, lovelyskin.com, dermstore.com, beautybay.com, reddit.com, and more
Questions and answers
How well does ISDIN Hyaluronic Concentrate work for dry skin?
ISDIN Hyaluronic Concentrate is an average fit for dry skin, offering moderate hydration through ingredients like glycerin and hydrolyzed hyaluronic acid while lacking enough richer softening and sealing ingredients for best moisture retention. A moisturizing treatment for dry skin needs rich moisturizing agents, nourishing extracts, and sealing ingredients to lock in hydration and support the skin barrier.
Which ingredients make this serum a good fit for dry skin?
Sodium hyaluronate, hydrolyzed hyaluronic acid, and glycerin make this serum a good fit for dry skin by pulling in moisture to hydrate. However, dry skin needs additional rich softening and sealing ingredients to lock that moisture in.
What does Hyaluronic Acid do for dry skin?
Hyaluronic acid draws moisture into dry skin, giving an immediate and lasting boost in hydration that helps smooth out fine lines and soften rough patches. It is very gentle and unlikely to cause irritation while improving overall skin smoothness and plumpness.
Dermatology and Therapy, 2021Journal of Drugs in Dermatology, 2011
What does Glycerin do for dry skin?
Glycerin helps dry skin by drawing in moisture and keeping it locked in, which makes the skin feel much softer and smoother. It also supports your natural skin barrier to stop water from escaping easily. A product for dry skin needs extra ingredients like hyaluronic acid and soothing plant extracts to truly calm and hydrate dry patches.
Clinical, Cosmetic and Investigational Dermatology, 2017The British Journal of Dermatology, 2008
Where does this serum go in a skincare routine for dry skin?
This serum goes in the evening routine after cleansing and before moisturizing, though some serums can also be used in the morning or twice a day. It is unlikely to cause irritation for your dry skin due to the absence of harsh ingredients.
Can I use this serum with retinol, and in what order?
You can use this treatment alongside retinol by applying the treatment first and following it with your moisturizer and retinol, or as part of a routine that uses barrier-enhancing moisturizers to support skin recovery. This approach helps maintain hydration while managing potential dryness from active ingredients.
Cutis, 2006Clinical, Cosmetic and Investigational Dermatology, 2017
How often should I use this serum?
You can use this treatment in your evening routine, applying it after cleansing and before your moisturizer. Some people may also use it in the morning or twice a day when their skin tolerates it well.
Can this serum clog pores, cause breakouts or purging for dry skin?
This serum is unlikely to clog pores, cause breakouts, or lead to purging for your dry skin due to its safe ingredients and lack of harsh irritants. It features a gentle formula that hydrates the skin well without causing irritation.
Can I use this serum around the eyes or on my body?
You can use this serum around the eyes, as the thin skin there benefits from lightweight hydration, but using it on the body may require richer creams with heavier oils and butters to lock in moisture.
Is this serum fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (parfum).
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability.
Aesthetic Plastic Surgery, 2026Profhilo gel combined with Dysport Botox significantly improved skin hydration, skin thickness, and GAIS scores compared to Dysport Botox injection alone in 19 participants seeking neck rejuvenation.
Dermatologic Therapy, 2022Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups.
Military Medicine, 2024Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms.
Clinical and Experimental Dermatology, 2007Externally applied substances such as ceramides, hyaluronic acid, licorice extracts, dimethicone, petrolatum, and paraffin wax treat skin disease resulting from damage to the skin barrier.
Clinics in Dermatology, 2012A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.
Journal of Cosmetic Dermatology, 2015Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.
Journal of Cosmetic Dermatology, 2026Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.
International Journal of Cosmetic Science, 2026
Why other moisturizers fit dry skin better
Daily consumption of fermented pomegranate extract drinks and serums improved skin moisture, brightness, elasticity, and collagen density while reducing spots in healthy subjects compared to baseline.
Journal of Cosmetic Dermatology, 2022Aged Punica granatum extract significantly reduced UV-induced erythema and melanin levels while improving skin hydration and lightness compared to placebo in 60 women.
Food Science & Nutrition, 2025Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.
Arzneimittel-Forschung, 2000
Ingredients
Water, Dimethicone, Propanediol, Glycerin, 1,2-Hexanediol, Sodium Acrylates Copolymer, Dimethicone Crosspolymer, Butylene Glycol, Pseudoalteromonas Extract Ferment, Glycereth-26, Lecithin, Maltodextrin, Sodium Benzoate, Pentylene Glycol, Lens Esculenta Seed Extract, Disodium Edta, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Xanthan Gum, Citric Acid, Biosaccharide Gum-1, Carbomer, Polysorbate 20, Sodium Lactate, Sodium Salicylate, Salicylic Acid, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Parfum
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Dr. Sofía Perea Pérez, MD, MSc
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Specialist dermatologist, MBBS, MD, IFAAD
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Elina Nazarenko, MD
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Dermatology and diagnostic consultant
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Victoria Derkova, MS
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Cosmetic chemist, cosmetic development technologist
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