Paula's Choice vs ISDIN
Paula's Choice and ISDIN are esteemed skincare brands offering serums, cleansers, moisturizers, toners, sunscreens, and eye products designed for diverse complexions. The American line, founded in 1995 and owned by Unilever since 2021, centers its creations on hyaluronic acid, glycerin, and vitamin c to best suit oily and acne-prone skin. Conversely, the Spanish house, established in 1975 and owned by Puig, crafts gentle yet effective formulas featuring reliable results that suit sensitive and acne-prone skin best. While both brands support healthy complexions through targeted solutions like specific toners, retinols, exfoliants, sunscreens, and eye treatments, they differ in their foundational ingredients and regional heritage.
Paula's Choice is an American skincare brand founded in 1995 and owned by Unilever since 2021.
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
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This page compares some of the most popular Paula's Choice and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Paula's Choice vs ISDIN products
People Say
Texture and Lightweight Feel Mostly MentionedMostly Mentioned
- “Provides an internal level of hydration without leaving any heavy finish. — Paula's Choice Skin Balancing Pore-Reducing Toner”
- “Absorbs quickly and leaves no greasy residue behind. — Paula's Choice Clear Oil-Free Moisturizer”
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
Brightness, Tone and Anti-Aging Mostly MentionedMostly Mentioned
- “visible glow — Paula's Choice C15 Super Booster”
- “skin looks plumper — Paula's Choice Pro-Collagen Multi-Peptide Booster”
- “helps reduce swelling in the area of my under-eye bags — ISDIN K-Ox Eyes”
- “Skin feels intensely hydrated — ISDIN Hyaluronic Concentrate”
Skin Texture Smoothing and Pores Mostly MentionedRarely Noted
- “cleared my bumps — Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant”
- “skin becomes very smooth — Paula's Choice 1% Retinol Treatment”
- “pores look smaller — Paula's Choice 10% Niacinamide Booster”
- “skin was much smoother — ISDIN Retinal Intense Serum”
Sensitive Skin and Gentle Care Often MentionedOften Mentioned
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
- “doesn't sting eyes — ISDIN Eryfotona Actinica”
- “Finally a vitamin C product I can use — Paula's Choice 25% Vitamin C + Glutathione Clinical Serum”
Acne and Blemish Control Often MentionedNot noted
- “Helped clear my cystic acne — Paula's Choice CLEAR Pore Normalizing Cleanser”
- “heals blemishes faster — Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant”
- “Removes all my makeup easily — Paula's Choice CLEAR Pore Normalizing Cleanser”
Makeup Compatibility and Finish Not notedOften Mentioned
- “doesn't leave you white as a ghost — ISDIN Fusion Water”
- “acts like a primer — ISDIN Eryfotona Actinica”
- “dries down matte — ISDIN Eryfotona Actinica”
High Price and Value Issues Mostly MentionedOften Mentioned
- “tiny tube — Paula's Choice 10% Azelaic Acid Booster”
- “Sooooo expensive — Paula's Choice 25% Vitamin C + Glutathione Clinical Serum”
- “very expensive — ISDIN Eryfotona Actinica”
- “My only wish is that ISDIN would make this product in a bigger size bottle. — ISDIN Fusion Water”
Unpleasant Smell or Scent Concerns Often MentionedOften Mentioned
- “smells like grain — Paula's Choice 10% Azelaic Acid Booster”
- “smells like hot dog water — Paula's Choice C15 Super Booster”
- “smell is overpowering — ISDIN Eryfotona Actinica”
- “lingering headache inducing effect — ISDIN K-Ox Eyes”
Packaging and Size Issues Often MentionedRarely Noted
- “Pump stopped working — ISDIN Hyaluronic Concentrate”
- “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum”
- “surprisingly small bottle — Paula's Choice Skin-Smoothing Retinol Body Treatment”
Product Formula and Stability Issues Sometimes NotedSometimes Noted
- “turned orange in weeks — Paula's Choice C15 Super Booster”
- “Did not notice any difference in my pores. — Paula's Choice Skin Balancing Pore-Reducing Toner”
- “did nothing — Paula's Choice 10% Niacinamide Booster”
- “don't see result — ISDIN K-Ox Eyes”
Paula's Choice vs ISDIN routines for dry skin
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Cleanser
CeraVe Hydrating Facial Cleanser
Morning · Evening · Once a week
€7.50
-
Hydrating Toner
COSRX Propolis Synergy Toner
Morning
€18.55
-
Moisturizer
Elizabeth Arden Advanced Ceramide Lift and Firm Night Cream
Morning · Evening · Once a week
€76.29
-
SPF
Fusion Water
Morning
€19.90
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€16.10
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€47.00
-
Nourishing Mask
Anua Heartleaf 77% Soothing Sheet Mask
Once a week
€19.90
-
Cleanser
CLEAR Pore Normalizing Cleanser
Morning · Evening · Once a week
€25.00
-
Hydrating Toner
Skin Recovery Enriched Calming Toner
Morning
€53.00
-
Moisturizer
Replenishing Moisturizer
Morning · Evening · Once a week
€58.00
-
SPF
Purito Daily Soft Touch Sunscreen
Morning
€12.98
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€16.10
-
Serum or Treatment
RESIST Super Antioxidant Concentrate Serum
Evening · Once a week
€57.00
-
Nourishing Mask
Anua Heartleaf 77% Soothing Sheet Mask
Once a week
€19.90
Paula's Choice vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
€11.35
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€19.99
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
€17.47
-
SPF
Eryfotona Actinica
Morning
€22.49
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€40.00
-
Cleansing Toner
Pixi Glow Tonic
Evening
€29.29
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€47.00
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€49.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
€79.97
-
Cleanser
CLEAR Pore Normalizing Cleanser
Morning · Evening · Once a week
€25.00
-
Hydrating Toner
Advanced Replenishing Toner
Morning · Once a week
€36.00
-
Moisturizer
Clear Oil-Free Moisturizer
Morning · Evening · Once a week
€42.00
-
SPF
make p:rem UV Defense Me Blue Ray Sun Cream
Morning
€34.30
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€40.00
-
Cleansing Toner
Pixi Glow Tonic
Evening
€29.29
-
Serum or Treatment
Niacinamide 20% Treatment
Evening · Once a week
€53.55
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€49.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
€79.97
Paula's Choice vs ISDIN routines for combination skin
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Cleanser
Paula's Choice Perfectly Balanced Foaming Cleanser
Morning · Evening · Once a week
€32.00
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
€17.47
-
SPF
Eryfotona Actinica
Morning
€22.49
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€40.00
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€17.15
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€47.00
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€49.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
€79.97
-
Cleanser
CLEAR Pore Normalizing Cleanser
Morning · Evening · Once a week
€25.00
-
Hydrating Toner
Advanced Replenishing Toner
Morning · Once a week
€36.00
-
Moisturizer
Clear Oil-Free Moisturizer
Morning · Evening · Once a week
€42.00
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€40.00
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€17.15
-
Serum or Treatment
Niacinamide 20% Treatment
Evening · Once a week
€53.55
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€49.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
€79.97
Questions and answers
Paula's Choice or ISDIN: which is better?
Paula's Choice works better for acne and pores, whereas ISDIN is better for sensitive skin and makeup compatibility.
What is the difference between Paula's Choice and ISDIN?
Paula's Choice offers fragrance-free formulas with particular strength in smoothing skin texture and controlling acne, while ISDIN stands out for its ultralight sunscreens and gentle care for sensitive skin.
Paula's Choice or ISDIN for dry skin?
ISDIN is the better fit for dry skin, offering a Superior routine fit compared to Paula's Choice, which achieves a High fit.
Paula's Choice or ISDIN: which moisturizer is better?
Both Paula's Choice and ISDIN offer effective moisturizers, but ISDIN may suit sensitive skin better while Paula's Choice works well for oily and acne-prone skin.
Which is more affordable, Paula's Choice or ISDIN?
Reviewers frequently note a high price for the products on this page from both Paula's Choice and ISDIN, meaning neither brand stands out as more affordable.
Which brand has better fragrance-free options?
Paula's Choice has better fragrance-free options because every product on its page lists no fragrance in its ingredients, whereas several ISDIN products contain fragrance.
Paula's Choice or ISDIN for oily skin?
Both Paula's Choice and ISDIN achieve a Superior Lovi fit level for oily skin. Paula's Choice features fragrance-free products on this page and does better for acne and blemish control, while ISDIN is mostly noted for ultralight sunscreens.
Paula's Choice or ISDIN: which sunscreen is better?
ISDIN offers ultralight, makeup-friendly, and skin-friendly sunscreens that fit sensitive skin at a Superior level and combination, oily, acne-prone, and dry skin at a High level, whereas Paula's Choice provides the Youth-Extending Daily Hydrating Fluid SPF 50 which fits dry and combination skin at a High level and oily, acne-prone, and sensitive skin at an Average level.
Paula's Choice or ISDIN for sensitive skin?
Both Paula's Choice and ISDIN offer a Superior Lovi fit level for sensitive skin. ISDIN does better for sensitive skin and gentle care, while Paula's Choice has no fragrance across the products on this page.
Paula's Choice or ISDIN for acne-prone skin?
Both Paula's Choice and ISDIN achieve a Superior routine fit for acne-prone skin, with Paula's Choice standing out specifically for acne and blemish control. Paula's Choice also features fragrance-free formulas across all products on this page.
Paula's Choice or ISDIN for dry sensitive skin?
ISDIN is a better fit for dry sensitive skin, achieving a Superior routine fit compared to the High fit level of Paula's Choice.
Paula's Choice or ISDIN for mature skin?
Both Paula's Choice and ISDIN fit mature skin well, as Lovi rates their routines as Superior. Paula's Choice offers numerous options with no fragrance, whereas ISDIN is particularly noted for ultralight sunscreens.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
Topical glutathione amino acid precursors protect skin against environmental and oxidative stress
Tocotrienol-rich fraction attenuates UV-induced inflammaging: A bench to bedside study
Chemical peels for acne vulgaris: a systematic review of randomised controlled trials
The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome
Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine
Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis
Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Novel beads made of alpha-cyclodextrin and oil for topical delivery of a lipophilic drug
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
Functional properties and skin care effects of sodium trehalose sulfate
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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